loz1 (SPAC25B8.19c)

Gene Standard Nameloz1 ChromosomeI
Systematic IDSPAC25B8.19c Gene Start4195228
SynonymsSPAC683.01c Gene End4192070
Producttranscription factor zf-C2H2 type (predicted) Gene Length3159
Feature Typeprotein coding CDS Start4194210
Name DescriptionLoss Of Zinc sensing CDS End4192642
Characterisation Statusbiological_role_inferred CDS Length1569

Ensembl Gene Location
  1. mal2
  2. SPAC25B8.15c
  3. SPAC25B8.16
  4. SPAC25B8.17
  5. SPAC25B8.18
  6. loz1
  7. SPAC683.03
  8. SPNCRNA.969
  9. SPAC683.02c
  10. SPNCRNA.970
  11. SPAC694.02
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyloz1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingISMPFAM:PF00096GO_REF:0000001
GO:0003677DNA bindingISMPFAM:PF00096GO_REF:0000001
GO:0008270zinc ion bindingIEAIPR007087GO_REF:0000002
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006355regulation of transcription, DNA-dependentISMPFAM:PF00096GO_REF:0000001
GO:0006357regulation of transcription from RNA polymerase II promoterNASGO_REF:0000051
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusISMPFAM:PF00096GO_REF:0000001
IDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
141952284192070

References

Region Start End Reference
three_prime_UTR41926414192070PMID:21511999
five_prime_UTR41952284194211PMID:21511999
three_prime_UTR41926414192070PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF13465 Pfam 482 507 10
SM00355 IPR015880 SMART Zinc finger, C2H2-like 496 520 28
SM00355 IPR015880 SMART Zinc finger, C2H2-like 468 490 28
PS50157 IPR007087 Prosite Profiles Zinc finger, C2H2 496 522 20
PS50157 IPR007087 Prosite Profiles Zinc finger, C2H2 468 495 20
PS00028 IPR007087 Prosite Patterns Zinc finger, C2H2 498 520 28
PS00028 IPR007087 Prosite Patterns Zinc finger, C2H2 470 490 28
G3DSA:3.30.160.60 IPR013087 Gene3D 468 495 13
G3DSA:3.30.160.60 IPR013087 Gene3D 496 521 13
SSF57667 SuperFamily 468 520 26
PTHR11389 hmmpanther 11 520 5

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000153zf-C2H2 typeTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000153

Protein Properties

Ave. residue weight 105.49 Da
Charge 10.00
Isoelectric point 7.50
Molecular weight 55.07 kDa
Number of residues 522
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2630.03PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2.9PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.3PMID:23101633
Species Distribution
DescriptionQualifierReference
orthologs cannot be distinguished
conserved in fungi
conserved in eukaryotes
conserved in eukaryotes only
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External References
Database Identifier Description
NBRP SPAC25B8.19c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC25B8.19c Retrieval of eukaryotic orthologs
BioGrid SPAC25B8.19c BioGRID Interaction Datasets
Bähler Lab SPAC25B8.19c Cell Cycle Expression Profile
Bähler Lab SPAC25B8.19c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC25B8.19c Pheromone response/mating expression profiles
Bähler Lab SPAC25B8.19c Environmental stress expression profiles
Bähler Lab SPAC25B8.19c Bähler Lab Transcriptome Viewer
Cyclebase SPAC25B8.19c Cell Cycle Data
PInt SPAC25B8.19c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC25B8.19c Entrez Gene
WikiGene2542738transcription factor zf-C2H2 type (predicted)
EntrezGene2542738transcription factor zf-C2H2 type (predicted)
SPD / RIKEN33/33B12Orfeome Localization Data
UniProtKB/SwissProtQ9UTA1Zinc finger protein C25B8.19c
ModBaseQ9UTA1Database of comparative protein structure models
Pfam Protein DomainsQ9UTA1Pfam Domain Arrangement
RefSeq PeptideNP_594479transcription factor zf-C2H2 type (predicted)
RefSeq mRNANM_001019908972h- transcription factor zf-C2H2 type (predicted) (SPAC25B8.19c), mRNA
European Nucleotide ArchiveCAB61785ENA Protein Mapping
UniParcUPI000006AB50UniProt Archive

Literature for loz1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013