rpl1101 (SPAC26A3.07c)


Gene Standard Namerpl1101 Characterisation Statusbiological role inferred
Systematic IDSPAC26A3.07c Feature Typeprotein coding
Synonyms Name Description
Product60S ribosomal protein L11 (predicted) Product Size174aa, 19.89 kDa
Genomic Location Chromosome I, 3346937-3346068 (870nt); CDS:3346859-3346335 (525nt)

Ensembl Gene Location
  1. chc1
  2. bud23
  3. rpl1101
  4. smb1
  5. rga2
  6. cnt6
GO Molecular Function
Term NameCount
rRNA binding57
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation469
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis337
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit64
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
sensitive to amphotericin Brpl1101Δ69
sensitive to clotrimazolerpl1101Δ107
sensitive to terbinafinerpl1101Δ102
slow vegetative cell population growthrpl1101Δ340
viable vegetative cell populationrpl1101Δ3831

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyrpl1101Δ3099
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3346937..3346068
5' UTR3346937..3346860PMID:21511999
3' UTR3346334..3346068PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00673 Pfam IPR031309 Ribosomal protein L5, C-terminal 64 161 3
PF00281 Pfam IPR031310 Ribosomal protein L5, N-terminal 7 60 3
PS00358 Prosite Patterns IPR020929 Ribosomal protein L5, conserved site 37 53 2
PTHR11994 HMMPANTHER 4 174 3
3.30.1440.10 Gene3D IPR022803 Ribosomal protein L5 domain 3 172 3
SSF55282 SuperFamily IPR022803 Ribosomal protein L5 domain 7 171 3
PIRSF002161 PIRSF IPR002132 Ribosomal protein L5 1 171 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.32 Da
Charge 16.50
Codon Adaptation Index 0.73
Isoelectric point 10.67
Molecular weight 19.89 kDa
Number of residues 174
Modifications

Protein Modifications

Term NameResidueCount
ubiquitinylated lysineK10, K35, K49, K64, K153, K166 512
Annotation ExtensionEvidenceResidueReference
IDA PMID:26412298
mass spectrometry evidence K10 PMID:26412298
mass spectrometry evidence K35 PMID:26412298
mass spectrometry evidence K49 PMID:26412298
mass spectrometry evidence K64 PMID:26412298
mass spectrometry evidence K153 PMID:26412298
mass spectrometry evidence K166 PMID:26412298
sumoylated lysine 173
Annotation ExtensionEvidenceResidueReference
IDA PMID:26404184
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rpl1101 (SPAC26A3.07c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
539483during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
466538during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
522378during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
525640during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
513949during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
35during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
4.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3422
conserved in vertebrates3397
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load gene that interact physically with SPAC26A3.07c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
affinity capturescdc42Rho family GTPase Cdc42 Affinity Capture-WesternPMID:18793338
affinity capturesrho2Rho family GTPase Rho2 Affinity Capture-WesternPMID:18793338
modifiesrho2Rho family GTPase Rho2 Biochemical ActivityPMID:18793338
Genetic Interactions

Source: BioGRID

Load gene that interact genetically with SPAC26A3.07c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withSPCC1682.06Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withser3D-3 phosphoglycerate dehydrogenase Ser3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcys11cysteine synthase Negative GeneticPMID:22681890
negative genetic interaction withSPAC23C11.07Schizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withtfs1transcription elongation factor TFIIS Negative GeneticPMID:22681890
negative genetic interaction withcox19mitochondrial respiratory chain complex IV assembly protein Cox19 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:22681890
negative genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:22681890
negative genetic interaction withomh5alpha-1,2-mannosyltransferase Omh5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC23A1.02cphosphoprotein phosphatase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdeg1tRNA-pseudouridine synthase Deg1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppk33serine/threonine protein kinase Ppk33 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsum2translation initiation inhibitor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspn2mitotic and meiotic (sporulation) septin Spn2 Negative GeneticPMID:22681890
negative genetic interaction withgms1UDP-galactose transmembrane transporter Gms1 Negative GeneticPMID:22681890
negative genetic interaction withstt41-phosphatidylinositol 4-kinase Stt4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC1348.12transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhmt2sulfide-quinone oxidoreductase Negative GeneticPMID:22681890
negative genetic interaction withabc2glutathione S-conjugate-exporting ATPase Abc2 Negative GeneticPMID:22681890
negative genetic interaction withwis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Negative GeneticPMID:22681890
negative genetic interaction withasl1cell wall protein Asl1, predicted O-glucosyl hydrolase Negative GeneticPMID:22681890
negative genetic interaction withSPAC144.05ATP-dependent DNA helicase/ ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC32A11.02cconserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC17H9.08mitochondrial coenzyme A transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnhp6High-mobility group non-histone chromatin protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsec74guanyl-nucleotide exchange factor Sec74 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmcp2pumilio family RNA-binding protein Mcp2 Negative GeneticPMID:22681890
negative genetic interaction withsnz1pyridoxine biosynthesis protein Negative GeneticPMID:22681890
negative genetic interaction withfsc1fasciclin domain protein Fsc1 Negative GeneticPMID:22681890
negative genetic interaction withSPAC1952.06cspliceosomal complex subunit (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1450.12PXA domain protein Negative GeneticPMID:22681890
negative genetic interaction withath2Ath1 complex protein Ath2 nuclease, XP-G family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsno1glutamine aminotransferase subunit Sno1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withime4mRNA (N6-adenosine)-methyltransferase Ime4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfml2ATP-dependent 3' to 5' DNA helicase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrps340S ribosomal protein S3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC24H6.11csulfate transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction witheri1double-strand siRNA ribonuclease Eri1 Negative GeneticPMID:22681890
negative genetic interaction withutr4methionine salvage haloacid dehalogenase-like hydrolase Utr4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witherg28Erg28 protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withclg1cyclin Clg1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppr2mitochondrial PPR repeat protein Ppr2 Negative GeneticPMID:22681890
negative genetic interaction withgmh4alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmet8siroheme synthase Met8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmug113T5orf172 family protein Negative GeneticPMID:22681890
negative genetic interaction withcch1calcium ion channel Cch1 Negative GeneticPMID:22681890
negative genetic interaction withnup132nucleoporin Nup132 Negative GeneticPMID:22681890
negative genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmug33Tea1-interacting protein involved in exocytosis Negative GeneticPMID:22681890
negative genetic interaction withyam8stretch-activated calcium ion channel Yam8 Negative GeneticPMID:22681890
phenotype enhanced byrga7Rho-type GTPase activating protein Rga7 Phenotypic EnhancementPMID:20164182
positive genetic interaction withpmp20thioredoxin peroxidase Pmp20 Positive GeneticPMID:22681890
positive genetic interaction withmoe1translation initiation factor eIF3d Moe1 Positive GeneticPMID:22681890
positive genetic interaction witharp6actin-like protein Arp6 Positive GeneticPMID:22681890
positive genetic interaction withSPBC1861.05pseudouridine-metabolizing bifunctional protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withcsn3COP9/signalosome complex subunit Csn3 (predicted) Positive GeneticPMID:22681890
synthetically rescued byrho2Rho family GTPase Rho2 Synthetic RescuePMID:18793338
synthetically rescued bymkh1MEK kinase (MEKK) Mkh1 Synthetic RescuePMID:18793338
synthetically rescuesags1alpha glucan synthase Ags1 Synthetic RescuePMID:18793338
External References
Database Identifier Description
NBRP SPAC26A3.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26A3.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26A3.07c BioGRID Interaction Datasets
Expression Viewer SPAC26A3.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26A3.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26A3.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26A3.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26A3.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26A3.07c Transcriptome Viewer (Bähler Lab)
GEO SPAC26A3.07c GEO profiles
PInt SPAC26A3.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC26A3.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC26A3.07c Fission yeast phenotypic data & analysis
Cyclebase SPAC26A3.07c.1 Cell Cycle Data
SPD / RIKEN05/05C03Orfeome Localization Data
UniProtKB/SwissProtP0CT7760S ribosomal protein L11-A
ModBaseP0CT77Database of comparative protein structure models
STRINGP0CT77Network display of known and predicted interactions and functional associations
UniProtKB/SwissProtP0CT7860S ribosomal protein L11-B
ModBaseP0CT78Database of comparative protein structure models
STRINGP0CT78Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59415060S ribosomal protein L11
RefSeq mRNANM_001019574972h- 60S ribosomal protein L11 (rpl1101), mRNA
European Nucleotide ArchiveAB016005ENA EMBL mapping
European Nucleotide ArchiveAF201080ENA EMBL mapping
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveAAF13719ENA Protein Mapping
European Nucleotide ArchiveBAA31552ENA Protein Mapping
European Nucleotide ArchiveCAA93230ENA Protein Mapping
European Nucleotide ArchiveCAB52808ENA Protein Mapping
UniParcUPI0000133B8FUniProt Archive

Literature for rpl1101

Search: Europe PMC or PubMed

Release Version: PomBase:30_57 - 27 Jan 2016