rpl1101 (SPAC26A3.07c)


Gene Standard Namerpl1101 Characterisation Statusbiological role inferred
Systematic IDSPAC26A3.07c Feature Typeprotein coding
Synonymsrpl11, rpl11-1 Name Description
Product60S ribosomal protein L11 (predicted) Product Size174aa, 19.89 kDa
Genomic Location Chromosome I, 3346937-3346068 (870nt); CDS:3346859-3346335 (525nt)

Ensembl Gene Location
  1. chc1
  2. bud23
  3. rpl1101
  4. smb1
  5. rga2
  6. cnt6
GO Molecular Function
Term NameCount
rRNA binding57
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation469
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis338
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit64
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
resistance to tamoxifenrpl1101Δ61
sensitive to amphotericin Brpl1101Δ69
sensitive to clotrimazolerpl1101Δ107
sensitive to terbinafinerpl1101Δ103
slow vegetative cell population growthrpl1101Δ357
viable vegetative cell populationrpl1101Δ3837

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyrpl1101Δ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3346937..3346068
5' UTR3346937..3346860PMID:21511999
3' UTR3346334..3346068PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00281 Pfam IPR031310 Ribosomal protein L5, N-terminal 7 60 3
PF00673 Pfam IPR031309 Ribosomal protein L5, C-terminal 64 161 3
PS00358 Prosite Patterns IPR020929 Ribosomal protein L5, conserved site 37 53 2
PTHR11994 HMMPANTHER 4 174 3
3.30.1440.10 Gene3D IPR022803 Ribosomal protein L5 domain 3 172 3
SSF55282 SuperFamily IPR022803 Ribosomal protein L5 domain 7 171 3
PIRSF002161 PIRSF IPR002132 Ribosomal protein L5 1 171 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.32 Da
Charge 16.50
Codon Adaptation Index 0.73
Isoelectric point 10.67
Molecular weight 19.89 kDa
Number of residues 174
Modifications

Protein Modifications

Term NameResidueCount
ubiquitinylated lysineK10, K35, K49, K64, K153, K166 512
Annotation ExtensionEvidenceResidueReference
mass spectrometry evidence K166 PMID:26412298
mass spectrometry evidence K49 PMID:26412298
mass spectrometry evidence K10 PMID:26412298
mass spectrometry evidence K35 PMID:26412298
mass spectrometry evidence K153 PMID:26412298
IDA PMID:26412298
mass spectrometry evidence K64 PMID:26412298
sumoylated lysine 173
Annotation ExtensionEvidenceResidueReference
IDA PMID:26404184
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rpl1101 (SPAC26A3.07c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
539483during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
466538during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
522378during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
525640during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
513949during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
35during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
4.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4605
conserved in eukaryotes4515
conserved in bacteria1001
conserved in metazoa3424
conserved in vertebrates3399
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC26A3.07c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bysog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
affinity captured bydsc1Golgi Dsc E3 ligase complex subunit Dsc1 Affinity Capture-MSPMID:21504829
affinity captured byair1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
affinity captured bynak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
affinity captured bycid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
affinity captured bypab2poly(A) binding protein Pab2 Affinity Capture-MSPMID:19336419
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPAC26A3.07c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
rescuescdc42Rho family GTPase Cdc42 Phenotypic SuppressionPMID:10628977
External References
Database Identifier Description
NBRP SPAC26A3.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26A3.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26A3.07c BioGRID Interaction Datasets
Expression Viewer SPAC26A3.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26A3.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26A3.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26A3.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26A3.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26A3.07c Transcriptome Viewer (Bähler Lab)
GEO SPAC26A3.07c GEO profiles
PInt SPAC26A3.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC26A3.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC26A3.07c Fission yeast phenotypic data & analysis
Cyclebase SPAC26A3.07c.1 Cell Cycle Data
SPD / RIKEN05/05C03Orfeome Localization Data
UniProtKB/SwissProtP0CT7760S ribosomal protein L11-A
ModBaseP0CT77Database of comparative protein structure models
STRINGP0CT77Network display of known and predicted interactions and functional associations
UniProtKB/SwissProtP0CT7860S ribosomal protein L11-B
ModBaseP0CT78Database of comparative protein structure models
STRINGP0CT78Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59415060S ribosomal protein L11
RefSeq mRNANM_001019574972h- 60S ribosomal protein L11 (rpl1101), mRNA

Literature for rpl1101

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016