rpl1101 (SPAC26A3.07c)


Gene Standard Namerpl1101 Characterisation Statusbiological_role_inferred
Systematic IDSPAC26A3.07c Feature Typeprotein coding
Synonymsrpl11, rpl11-1 Name Description
Product60S ribosomal protein L11 (predicted) Product Size174aa, 19.89 kDa
Genomic Location Chromosome I, 3346937-3346068 (870nt); CDS:3346859-3346335 (525nt)

Ensembl Gene Location
  1. chc1
  2. bud23
  3. rpl1101
  4. smb1
  5. rga2
  6. cnt6
GO Molecular Function
Term NameCount
rRNA binding56
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation473
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis337
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2315
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit65
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002642sensitive to amphotericin BCell growth assayrpl1101ΔNullPECO:0000137, PECO:0000005PMID:2225281769
FYPO:0002640sensitive to clotrimazole105
expressivity FYPO_EXT:0000002Cell growth assayrpl1101ΔNullPECO:0000137, PECO:0000005PMID:22252817
FYPO:0002328sensitive to terbinafine101
expressivity FYPO_EXT:0000003Cell growth assayrpl1101ΔNullPECO:0000137, PECO:0000005PMID:22252817
FYPO:0002060viable vegetative cell populationMicroscopyrpl1101ΔNullPMID:204732893759
Microscopyrpl1101ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001Microscopyrpl1101ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
133469373346068

UTRs

Region Coordinates Reference
five_prime_UTR3346937..3346860PMID:21511999
three_prime_UTR3346334..3346068PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00673 Pfam IPR002132 Ribosomal protein L5 64 144 3
PF00281 Pfam IPR002132 Ribosomal protein L5 7 60 2
PS00358 Prosite Patterns IPR020929 Ribosomal protein L5, conserved site 37 53 2
PTHR11994 HMMPANTHER IPR002132 Ribosomal protein L5 3 174 3
PTHR11994:SF2 HMMPANTHER 3 174 2
3.30.1440.10 Gene3D IPR022803 Ribosomal protein L5 domain 3 172 3
SSF55282 SuperFamily IPR022803 Ribosomal protein L5 domain 7 171 3
PIRSF002161 PIRSF IPR002132 Ribosomal protein L5 1 172 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.32 Da
Charge 16.50
Isoelectric point 10.67
Molecular weight 19.89 kDa
Number of residues 174
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
539483during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
466538during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
522378during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
525640during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
513949during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
35during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
4.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4600
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3425
conserved in vertebrates3400
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
air1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
pab2poly(A) binding protein Pab2 Affinity Capture-MSPMID:19336419
sog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Affinity Capture-MSPMID:21504829
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
cdc42Rho family GTPase Cdc42 Phenotypic SuppressionPMID:10628977
External References
Database Identifier Description
NBRP SPAC26A3.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26A3.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26A3.07c BioGRID Interaction Datasets
Expression Viewer SPAC26A3.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26A3.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26A3.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26A3.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26A3.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26A3.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC26A3.07c Cell Cycle Data
GEO SPAC26A3.07c GEO profiles
PInt SPAC26A3.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC26A3.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC26A3.07c Fission yeast phenotypic data & analysis
SPD / RIKEN05/05C03Orfeome Localization Data
UniProtKB/SwissProtQ1015760S ribosomal protein L11
ModBaseQ10157Database of comparative protein structure models
STRINGQ10157Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59415060S ribosomal protein L11
RefSeq mRNANM_001019574972h- 60S ribosomal protein L11 (rpl1101), mRNA
European Nucleotide ArchiveAB016005ENA EMBL mapping
European Nucleotide ArchiveAF201080ENA EMBL mapping
European Nucleotide ArchiveCAA93230.1ENA Protein Mapping
European Nucleotide ArchiveCAB52808.1ENA Protein Mapping
UniParcUPI0000133B8FUniProt Archive

Literature for rpl1101

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014