etr1 (SPAC26F1.04c)

Gene Standard Nameetr1 Characterisation Statusbiological role inferred
Systematic IDSPAC26F1.04c Feature Typeprotein coding
Synonyms Name Description
Productenoyl-[acyl-carrier protein] reductase (predicted) Product Size372aa, 41.23 kDa
Genomic Location Chromosome I, 5177808-5179736 (1929nt); CDS:5178325-5179443 (1119nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
enoyl-[acyl-carrier-protein] reductase activity2
Annotation ExtensionEvidenceWith/FromReference
trans-2-enoyl-CoA reductase (NADPH) activity2
Annotation ExtensionEvidenceWith/FromReference
zinc ion binding239
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
fatty acid biosynthetic process30
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
resistance to hydrogen peroxideetr1Δ73
sensitive to caffeine during vegetative growthetr1Δ106
sensitive to rapamycinetr1Δ78
viable vegetative cell populationetr1Δ3815

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyetr1Δ3095
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR5177808..5178324PMID:21511999
3' UTR5179444..5179736PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00107 Pfam IPR013149 Alcohol dehydrogenase, C-terminal 186 318 11
SM00829 SMART IPR020843 Polyketide synthase, enoylreductase domain 30 368 10
PTHR11695:SF15 HMMPANTHER 20 370 1
PTHR11695 HMMPANTHER IPR002085 Alcohol dehydrogenase superfamily, zinc-type 20 370 12 Gene3D IPR011032 GroES-like 16 117 12 Gene3D IPR016040 NAD(P)-binding domain 156 333 100
SSF51735 SuperFamily 148 331 88
SSF50129 SuperFamily IPR011032 GroES-like 20 191 13
Coil ncoils Rabaptin coiled-coil domain 211 231 1048

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.83 Da
Charge 11.50
Codon Adpatation Index 0.46
Isoelectric point 9.41
Molecular weight 41.23 kDa
Number of residues 372

Protein Modifications

Term NameResidueCount
phosphorylated residue 1930
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
71098during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
67634during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
64189during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
73878during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
3406.58during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
72179during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
8213.21during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.8during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.57during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3421
conserved in vertebrates3396

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPAC26F1.04c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26F1.04c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26F1.04c BioGRID Interaction Datasets
Expression Viewer SPAC26F1.04c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26F1.04c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26F1.04c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26F1.04c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26F1.04c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26F1.04c Transcriptome Viewer (Bähler Lab)
GEO SPAC26F1.04c GEO profiles
PInt SPAC26F1.04c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC26F1.04c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC26F1.04c Fission yeast phenotypic data & analysis
Cyclebase SPAC26F1.04c.1 Cell Cycle Data
SPD / RIKEN17/17F03Orfeome Localization Data
IntEnz1.3.1.-Integrated relational Enzyme database
Rhea1.3.1.-Annotated reactions database
UniProtKB/SwissProtQ10488Probable trans-2-enoyl-CoA reductase, mitochondrial
ModBaseQ10488Database of comparative protein structure models
STRINGQ10488Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594891enoyl-
RefSeq mRNANM_001020320972h- enoyl-[acyl-carrier protein] reductase (predicted) (etr1), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAA97361ENA Protein Mapping
European Nucleotide ArchiveCAA97361.1ENA Protein Mapping
UniParcUPI000012F564UniProt Archive

Literature for etr1

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015