gyp51 (SPAC26F1.09)

Gene Standard Namegyp51 ChromosomeI
Systematic IDSPAC26F1.09 Gene Start5167012
Synonyms Gene End5163555
ProductGTPase activating protein Gyp51 (predicted) Gene Length3458
Feature Typeprotein coding CDS Start5166836
Name Description CDS End5163741
Characterisation Statusbiological_role_inferred CDS Length3096

Ensembl Gene Location
  1. SPAC26F1.11
  2. pyp1
  3. gyp51
  4. SPAC26F1.08c
  5. SPAC26F1.07
  6. SPNCRNA.1055
  7. SPNCRNA.90
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopygyp51delta (deletion)deletionPMID:20473289
GO Molecular Function

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0005097Rab GTPase activator activityISOSGD:S000006170GO_REF:0000024
GO Biological Process

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0006887exocytosisIEAUniProtKB:KW-0268GO_REF:0000037
GO:0006888ER to Golgi vesicle-mediated transportISOSGD:S000006170GO_REF:0000024
GO:0015031protein transportIEAUniProtKB:KW-0653GO_REF:0000037
GO:0032313regulation of Rab GTPase activityISMPFAM:PF00566GO_REF:0000024
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0005798Golgi-associated vesicleISOSGD:S000006170GO_REF:0000024
GO:0005829cytosolIDAPMID:16823372
ISOSGD:S000006170GO_REF:0000024
GO:0005886plasma membraneISOSGD:S000006170GO_REF:0000024
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
151670125163555

References

Region Start End Reference
five_prime_UTR51670125166837PMID:21511999
five_prime_UTR51670125166837PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00566 IPR000195 Pfam Rab-GTPase-TBC domain 619 826 13
SM00164 IPR000195 SMART Rab-GTPase-TBC domain 569 829 13
PS50086 IPR000195 Prosite Profiles Rab-GTPase-TBC domain 610 806 13
G3DSA:1.10.8.270 Gene3D 612 728 12
SSF47923 IPR000195 SuperFamily 742 842 13
SSF47923 IPR000195 SuperFamily 600 766 13
Coil ncoils Rabaptin coiled-coil domain 936 964 974
Coil ncoils Rabaptin coiled-coil domain 986 1007 974
PTHR22957 hmmpanther 1 1029 12
PTHR22957:SF43 hmmpanther 1 1029 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Protein Properties

Ave. residue weight 112.79 Da
Charge -93.00
Isoelectric point 4.15
Molecular weight 116.29 kDa
Number of residues 1031
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2045.26PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide3895.98PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.74PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2.5PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Contact Curators
Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
SPAC821.05translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
nrm1negative regulator of MBF Negative GeneticPMID:22681890
mpr1histidine-containing response regulator phosphotransferase Mpr1 Positive GeneticPMID:22681890
ask1DASH complex subunit Ask1 Positive GeneticPMID:22681890
SPBC839.03cneddylation protein Dcn1 (predicted) Negative GeneticPMID:22681890
SPAC1565.07cTATA-binding protein (predicted) Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
dad2DASH complex subunit Dad2 Positive GeneticPMID:22681890
SPCC11E10.07ctranslation initiation factor eIF2B alpha subunit (predicted) Positive GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
Contact Curators
External References
Database Identifier Description
NBRP SPAC26F1.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26F1.09 Retrieval of eukaryotic orthologs
BioGrid SPAC26F1.09 BioGRID Interaction Datasets
Bähler Lab SPAC26F1.09 Cell Cycle Expression Profile
Bähler Lab SPAC26F1.09 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC26F1.09 Pheromone response/mating expression profiles
Bähler Lab SPAC26F1.09 Environmental stress expression profiles
Bähler Lab SPAC26F1.09 Bähler Lab Transcriptome Viewer
Cyclebase SPAC26F1.09 Cell Cycle Data
PInt SPAC26F1.09 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC26F1.09 Entrez Gene
WikiGene2542680GTPase activating protein Gyp51 (predicted)
EntrezGene2542680GTPase activating protein Gyp51 (predicted)
SPD / RIKEN30/30A05Orfeome Localization Data
UniProtKB/SwissProtQ10496TBC domain-containing protein C26F1.09
ModBaseQ10496Database of comparative protein structure models
Pfam Protein DomainsQ10496Pfam Domain Arrangement
RefSeq PeptideNP_594886GTPase activating protein Gyp51 (predicted)
RefSeq mRNANM_001020315972h- GTPase activating protein Gyp51 (predicted) (gyp51), mRNA
European Nucleotide ArchiveCAA97366ENA Protein Mapping
UniParcUPI000013A984UniProt Archive

Literature for gyp51
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013