SPAC26H5.07c


Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPAC26H5.07c Feature Typeprotein coding
Synonyms Name Description
Productseven transmembrane receptor protein (predicted) Product Size505aa, 56.86 kDa
Genomic Location Chromosome I, 4133498-4131406 (2093nt); CDS:4133463-4131566 (1898nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
receptor activity10
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process

GO Slim Terms

signaling


Term NameCount
cell surface receptor signaling pathway5
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytoplasm4212
Annotation ExtensionEvidenceWith/FromReference
integral component of plasma membrane49
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
increased cell population growth rateSPAC26H5.07cΔ256
viable vegetative cell populationSPAC26H5.07cΔ3844

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologySPAC26H5.07cΔ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4133498..4133377, 4133299..4133227, 4132923..4131406
Intron4133376..4133300, 4133226..4132924
mRNA4133498..4131406
5' UTR4133498..4133464PMID:21511999
CDS4133463..4133377, 4133299..4133227, 4132923..4131566
3' UTR4131565..4131406PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06814 Pfam IPR009637 Lung seven transmembrane receptor-like 140 431 2
TMhelix TMHMM 400 422 953
TMhelix TMHMM 215 237 953
TMhelix TMHMM 181 203 953
TMhelix TMHMM 291 310 953
TMhelix TMHMM 2 20 953
TMhelix TMHMM 320 342 953
TMhelix TMHMM 363 385 953
TMhelix TMHMM 264 286 953
PTHR21229 HMMPANTHER IPR009637 Lung seven transmembrane receptor-like 65 493 2
PTHR21229:SF1 HMMPANTHER 65 493 2
SignalP-noTM signalp 1 22 207

View domain organization at Pfam

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 112.59 Da
Charge -6.50
Codon Adaptation Index 0.58
Isoelectric point 5.39
Molecular weight 56.86 kDa
Number of residues 505
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPAC26H5.07c

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3015.52during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
7522.98during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6.9during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
1.3during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4606
conserved in eukaryotes4516
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2505
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC26H5.07c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byred1RNA elimination defective protein Red1 Affinity Capture-MSPMID:24713849
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPAC26H5.07c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withdsc5UBX domain containing protein required for Sre1 cleavage Negative GeneticPMID:22681890
negative genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:22681890
negative genetic interaction withpst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
negative genetic interaction withers1RNA-silencing factor Ers1 Negative GeneticPMID:22681890
negative genetic interaction withymr1phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC26H5.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26H5.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26H5.07c BioGRID Interaction Datasets
Expression Viewer SPAC26H5.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26H5.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26H5.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26H5.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26H5.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26H5.07c Transcriptome Viewer (Bähler Lab)
GEO SPAC26H5.07c GEO profiles
PInt SPAC26H5.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC26H5.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC26H5.07c Fission yeast phenotypic data & analysis
Cyclebase SPAC26H5.07c.1 Cell Cycle Data
SPD / RIKEN26/26E10Orfeome Localization Data
UniProtKB/SwissProtO13989Uncharacterized protein C26H5.07c
ModBaseO13989Database of comparative protein structure models
STRINGO13989Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594454seven transmembrane receptor protein (predicted)
RefSeq mRNANM_001019883972h- seven transmembrane receptor protein (predicted) (SPAC26H5.07c), mRNA
European Nucleotide ArchiveBAA87278.1ENA Protein Mapping
European Nucleotide ArchiveCAB16193.2ENA Protein Mapping
UniParcUPI000006A353UniProt Archive

Literature for SPAC26H5.07c

Search: Europe PMC or PubMed

Release Version: PomBase:30_60 - 12 May 2016