SPAC26H5.07c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC26H5.07c Feature Typeprotein coding
Synonyms Name Description
Productseven transmembrane receptor protein (predicted) Product Size505aa, 56.86 kDa
Genomic Location Chromosome I, 4133498-4131406 (2093nt); CDS:4133463-4131566 (1898nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004872receptor activityISMPFAM:PF06814GO_REF:000000110
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0007166cell surface receptor signaling pathwayISMPFAM:PF06814GO_REF:000000126
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005737cytoplasmIDAPMID:168233724198
GO:0005887integral component of plasma membraneISMPFAM:PF06814GO_REF:000000151
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPAC26H5.07cΔNullPMID:204732893755
MicroscopySPAC26H5.07cΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopySPAC26H5.07cΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
141334984133377
241332994133227
341329234131406

UTRs

Region Start End Reference
three_prime_UTR41315654131406PMID:21511999
five_prime_UTR41334984133464PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06814 Pfam IPR009637 Transmembrane receptor, eukaryota 140 431 2
TMhelix TMHMM 215 237 959
TMhelix TMHMM 2 20 959
TMhelix TMHMM 320 342 959
TMhelix TMHMM 181 203 959
TMhelix TMHMM 291 310 959
TMhelix TMHMM 264 286 959
TMhelix TMHMM 363 385 959
TMhelix TMHMM 400 422 959
PTHR21229 HMMPANTHER IPR009637 Transmembrane receptor, eukaryota 21 493 2
PTHR21229:SF1 HMMPANTHER 21 493 2
Low complexity (SEG) seg 295 312
Low complexity (SEG) seg 392 406
Low complexity (SEG) seg 411 423
Low complexity (SEG) seg 450 461
SignalP-noTM signalp 1 22 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide278
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 112.59 Da
Charge -6.50
Isoelectric point 5.39
Molecular weight 56.86 kDa
Number of residues 505
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
3015.52during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
7522.98during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.3during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
6.9during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dsc5UBX domain containing protein required for Sre1 cleavage Negative GeneticPMID:22681890
ymr1phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Negative GeneticPMID:22681890
ers1RNA-silencing factor Ers1 Negative GeneticPMID:22681890
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
pst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC26H5.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26H5.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26H5.07c BioGRID Interaction Datasets
Expression Viewer SPAC26H5.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26H5.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26H5.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26H5.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26H5.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26H5.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC26H5.07c Cell Cycle Data
GEO SPAC26H5.07c GEO profiles
PInt SPAC26H5.07c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2542691seven transmembrane receptor-like protein
EntrezGene2542691seven transmembrane receptor-like protein
SPD / RIKEN26/26E10Orfeome Localization Data
UniProtKB/SwissProtO13989Uncharacterized protein C26H5.07c
ModBaseO13989Database of comparative protein structure models
StringO13989Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594454seven transmembrane receptor-like protein
RefSeq mRNANM_001019883972h- seven transmembrane receptor-like protein (SPAC26H5.07c), mRNA
European Nucleotide ArchiveBAA87278ENA Protein Mapping
European Nucleotide ArchiveCAB16193ENA Protein Mapping
UniParcUPI000006A353UniProt Archive

Literature for SPAC26H5.07c

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014