bgl2 (SPAC26H5.08c)

Gene Standard Namebgl2 Characterisation Statusbiological_role_inferred
Systematic IDSPAC26H5.08c Feature Typeprotein coding
Synonyms Name Description
Productglucan beta-glucosidase Bgl2 (predicted) Product Size321aa, 35.41 kDa
Genomic Location Chromosome I, 4136031-4134378 (1654nt); CDS:4135587-4134622 (966nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
glucan exo-1,3-beta-glucosidase activity1
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
fungal-type cell wall beta-glucan metabolic process15
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
fungal-type cell wall34
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationbgl2ΔNull3781

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphology3092
penetrance FYPO_EXT:0000001bgl2ΔNull
Target Of
FYPO affected by mutation in lkh1 dual specificity protein kinase Lkh1 PMID:23956636
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00332 Pfam IPR000490 Glycoside hydrolase, family 17 43 318 1
PS00587 Prosite Patterns IPR000490 Glycoside hydrolase, family 17 238 251 1
PTHR16631 HMMPANTHER 1 321 1
PTHR16631:SF6 HMMPANTHER 1 321 1 Gene3D IPR013781 Glycoside hydrolase, catalytic domain 45 318 22
SSF51445 SuperFamily IPR017853 Glycoside hydrolase superfamily 50 318 28
SignalP-noTM signalp 1 21 212

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.32 Da
Charge -22.50
Isoelectric point 3.99
Molecular weight 35.41 kDa
Number of residues 321
Gene Expression

Qualitative Gene Expression

RNA levelincreased in presence of purvalanol A expression microarray evidencePMID:22840777

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
329.24during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
10during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
1.7during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4604
conserved in eukaryotes4516

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
swd2Set1C complex subunit Swd2.1 Negative GeneticPMID:22681890
clr1SHREC complex subunit Clr1 Negative GeneticPMID:22681890
not2CCR4-Not complex subunit Not2 (predicted) Negative GeneticPMID:22681890
php3CCAAT-binding factor complex subunit Php3 Negative GeneticPMID:22681890
tps1alpha,alpha-trehalose-phosphate synthase Negative GeneticPMID:22681890
psy2protein phosphatase PP4 complex subunit Psy2 (predicted) Negative GeneticPMID:22681890
php5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
xap5xap-5-like protein Negative GeneticPMID:24957674
vps5retromer complex subunit Vps5 Negative GeneticPMID:22681890
far10SIP/FAR complex FHA domain subunit Far10/Csc1 Negative GeneticPMID:22681890
SPBC1861.07elongin C (predicted) Negative GeneticPMID:22681890
glc8protein phosphatase regulatory subunit Glc8 (predicted) Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
swr1SNF2 family ATP-dependent DNA helicase Swr1 Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC26H5.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26H5.08c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26H5.08c BioGRID Interaction Datasets
Expression Viewer SPAC26H5.08c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26H5.08c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26H5.08c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26H5.08c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26H5.08c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26H5.08c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC26H5.08c Cell Cycle Data
GEO SPAC26H5.08c GEO profiles
PInt SPAC26H5.08c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC26H5.08c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC26H5.08c Fission yeast phenotypic data & analysis
IntEnz3.2.1.58Integrated relational Enzyme database
Rhea3.2.1.58Annotated reactions database
SPD / RIKEN13/13G01Orfeome Localization Data
UniProtKB/SwissProtO13990Glucan 1,3-beta-glucosidase
ModBaseO13990Database of comparative protein structure models
STRINGO13990Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594455glucan beta-glucosidase Bgl2 (predicted)
RefSeq mRNANM_001019884972h- glucan beta-glucosidase Bgl2 (predicted) (bgl2), mRNA
European Nucleotide ArchiveAB000539ENA EMBL mapping
European Nucleotide ArchiveCAB16200.1ENA Protein Mapping
UniParcUPI000006C8AEUniProt Archive

Literature for bgl2

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015