bgl2 (SPAC26H5.08c)


Gene Standard Namebgl2 Characterisation Statusbiological_role_inferred
Systematic IDSPAC26H5.08c Feature Typeprotein coding
Synonyms Name Description
Productglucan beta-glucosidase Bgl2 (predicted) Product Size321aa, 35.41 kDa
Genomic Location Chromosome I, 4136031-4134378 (1654nt); CDS:4135587-4134622 (966nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
glucan exo-1,3-beta-glucosidase activity1
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
fungal-type cell wall beta-glucan metabolic process15
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
fungal-type cell wall34
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationbgl2ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologybgl2ΔNull3094
Target Of
OntologyRelationshipGeneProduct
FYPO affected by mutation in lkh1 dual specificity protein kinase Lkh1
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4136031..4134378
mRNA4136031..4134378
5' UTR4136031..4135588PMID:21511999
CDS4135587..4134622
3' UTR4134621..4134378SPAB539
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00332 Pfam IPR000490 Glycoside hydrolase, family 17 43 318 1
PS00587 Prosite Patterns IPR000490 Glycoside hydrolase, family 17 238 251 1
PTHR16631:SF6 HMMPANTHER 1 321 1
PTHR16631 HMMPANTHER 1 321 1
3.20.20.80 Gene3D IPR013781 Glycoside hydrolase, catalytic domain 45 318 22
SSF51445 SuperFamily IPR017853 Glycoside hydrolase superfamily 50 318 28
SignalP-noTM signalp 1 21 212

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.32 Da
Charge -22.50
Isoelectric point 3.99
Molecular weight 35.41 kDa
Number of residues 321
Modifications

Protein Modifications

Term NameResidueCount
glycosylated residue 36
Annotation ExtensionEvidenceResidueReference
ISS PMID:0000001
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreased in presence of purvalanol A expression microarray evidencePMID:22840777

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
329.24during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
10during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
1.7during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4603
conserved in eukaryotes4514
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
negative genetic interaction withclr1SHREC complex subunit Clr1 Negative GeneticPMID:22681890
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
negative genetic interaction withfar10SIP/FAR complex FHA domain subunit Far10/Csc1 Negative GeneticPMID:22681890
negative genetic interaction withglc8protein phosphatase regulatory subunit Glc8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
negative genetic interaction withnot2CCR4-Not complex subunit Not2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
negative genetic interaction withphp3CCAAT-binding factor complex subunit Php3 Negative GeneticPMID:22681890
negative genetic interaction withphp5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
negative genetic interaction withpsy2protein phosphatase PP4 complex subunit Psy2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
negative genetic interaction withSPBC1861.07elongin C (predicted) Negative GeneticPMID:22681890
negative genetic interaction withswd2Set1C complex subunit Swd2.1 Negative GeneticPMID:22681890
negative genetic interaction withswr1SNF2 family ATP-dependent DNA helicase Swr1 Negative GeneticPMID:22681890
negative genetic interaction withtps1alpha,alpha-trehalose-phosphate synthase Negative GeneticPMID:22681890
negative genetic interaction withvps5retromer complex subunit Vps5 Negative GeneticPMID:22681890
negative genetic interaction withxap5xap-5-like protein Negative GeneticPMID:24957674
External References
Database Identifier Description
NBRP SPAC26H5.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC26H5.08c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC26H5.08c BioGRID Interaction Datasets
Expression Viewer SPAC26H5.08c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC26H5.08c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC26H5.08c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC26H5.08c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC26H5.08c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC26H5.08c Transcriptome Viewer (Bähler Lab)
GEO SPAC26H5.08c GEO profiles
PInt SPAC26H5.08c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC26H5.08c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC26H5.08c Fission yeast phenotypic data & analysis
Cyclebase SPAC26H5.08c.1 Cell Cycle Data
IntEnz3.2.1.58Integrated relational Enzyme database
Rhea3.2.1.58Annotated reactions database
SPD / RIKEN13/13G01Orfeome Localization Data
UniProtKB/SwissProtO13990Glucan 1,3-beta-glucosidase
ModBaseO13990Database of comparative protein structure models
STRINGO13990Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594455glucan beta-glucosidase Bgl2 (predicted)
RefSeq mRNANM_001019884972h- glucan beta-glucosidase Bgl2 (predicted) (bgl2), mRNA
European Nucleotide ArchiveAB000539ENA EMBL mapping
European Nucleotide ArchiveCAB16200.1ENA Protein Mapping
UniParcUPI000006C8AEUniProt Archive

Literature for bgl2

Search: Europe PMC or PubMed

Release Version: PomBase:26_52 - 11 May 2015