SPAC29B12.14c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC29B12.14c Feature Typeprotein coding
Synonyms Name Description
Productpurine transporter (predicted) Product Size590aa, 65.23 kDa
Genomic Location Chromosome I, 5442552-5439647 (2906nt); CDS:5441621-5439849 (1773nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015505uracil:cation symporter activityISOSGD:S000000225GO_REF:00000242
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006812cation transportISOSGD:S000000225GO_REF:0000024139
GO:0034220ion transmembrane transportISOSGD:S000000225GO_REF:0000024187
GO:0015931nucleobase-containing compound transportISOSGD:S000000225GO_REF:000002484
GO:0006862nucleotide transportNASGO_REF:000005118
GO:0072531pyrimidine-containing compound transmembrane transportISOSGD:S000000225GO_REF:00000249
GO:0015857uracil transportISOSGD:S000000225GO_REF:00000242
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722317
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
GO:0005634nucleusIDAPMID:168233722730
GO:0005886plasma membraneISOSGD:S000000225GO_REF:0000024243
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPAC29B12.14cΔNullPMID:204732893755
MicroscopySPAC29B12.14cΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopySPAC29B12.14cΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
154425525439647

UTRs

Region Start End Reference
three_prime_UTR54398485439647PMID:21511999
five_prime_UTR54425525441622PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02133 Pfam IPR001248 Permease, cytosine/purines, uracil, thiamine, allantoin 55 506 3
TMhelix TMHMM 417 439 959
TMhelix TMHMM 351 373 959
TMhelix TMHMM 194 213 959
TMhelix TMHMM 93 115 959
TMhelix TMHMM 388 410 959
TMhelix TMHMM 501 523 959
TMhelix TMHMM 257 279 959
TMhelix TMHMM 223 245 959
TMhelix TMHMM 466 488 959
TMhelix TMHMM 135 157 959
TMhelix TMHMM 294 316 959
PTHR30618 HMMPANTHER 1 582 3
PTHR30618:SF0 HMMPANTHER 1 582 3
Low complexity (SEG) seg 406 422
TIGR00800 tigrfam IPR012681 Nucleobase cation symporter-1, NCS1 50 491 2

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 110.56 Da
Charge 8.00
Isoelectric point 8.09
Molecular weight 65.23 kDa
Number of residues 590
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreasedexpression microarray evidencePMID:12529438
during GO:0034599

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1606.16during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.84during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
1.3during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999426
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4564
conserved in eukaryotes4482
conserved in bacteria1001
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC29B12.14c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC29B12.14c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC29B12.14c BioGRID Interaction Datasets
Expression Viewer SPAC29B12.14c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC29B12.14c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC29B12.14c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC29B12.14c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC29B12.14c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC29B12.14c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC29B12.14c Cell Cycle Data
GEO SPAC29B12.14c GEO profiles
PInt SPAC29B12.14c Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene2541559purine transporter (predicted)
WikiGene2541559purine transporter (predicted)
SPD / RIKEN45/45G04Orfeome Localization Data
UniProtKB/SwissProtO14035Uncharacterized permease C29B12.14c
ModBaseO14035Database of comparative protein structure models
StringO14035Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594991purine transporter (predicted)
RefSeq mRNANM_001020422972h- purine transporter (predicted) (SPAC29B12.14c), mRNA
European Nucleotide ArchiveCAB16258ENA Protein Mapping
UniParcUPI000228F45AUniProt Archive

Literature for SPAC29B12.14c

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014