nnf1 (SPAC29E6.04)

Gene Standard Namennf1 ChromosomeI
Systematic IDSPAC29E6.04 Gene Start4409773
SynonymsSPAC30.08 Gene End4410391
Productkinetochore protein Nnf1 Gene Length619
Feature Typeprotein coding CDS Start4409773
Name Description CDS End4410391
Characterisation Statuspublished CDS Length619

Ensembl Gene Location
  1. pof11
  2. prp3
  3. uso1
  4. mxr1
  5. nnf1
  6. SPAC29E6.06c
  7. SPAC29E6.07
  8. tbp1
  9. SPAC29E6.09
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000121abnormal sporulationnnf1delta (deletion)deletionPMID:20404563
FYPO:0000279formation of azygotic ascus upon sporulationnnf1delta (deletion)deletionPMID:20404563
FYPO:0002061inviable vegetative cell populationMicroscopynnf1delta (deletion)deletionPMID:20473289
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000070mitotic sister chromatid segregation
requiredICGO:0000939GO_REF:0000001
GO:0007127meiosis IIEPPMID:12161753
GO:0071444cellular response to pheromoneIMPPMID:17035632
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000779condensed chromosome, centromeric region
exists_during mitotic prophaseIDAPMID:17035632
GO:0000818nuclear MIS12/MIND complexNASGO_REF:0000001
GO:0005634nucleusICGO:0031617GO_REF:0000001
GO:0031617NMS complexIDAPMID:16079914
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
144097734410192
244101944410391
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF03980 IPR007128 Pfam Nnf1 39 143 1
Coil ncoils Rabaptin coiled-coil domain 117 138 974
PIRSF027153 IPR016851 PIRSF Kinetochore-associated protein Nnf1p 1 189 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.68 Da
Charge -4.50
Isoelectric point 5.40
Molecular weight 23.71 kDa
Number of residues 205
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide1.5PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.31PMID:23101633
Warning
DescriptionQualifierReference
frameshifted
sequence error in genomic data PMID:17035632
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
mis12kinetochore protein Mis12 Dosage RescuePMID:15502821
mis14kinetochore protein Mis14 Dosage RescuePMID:15502821
hos2histone deacetylase (class I) Hos2 Dosage RescuePMID:17352737
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
spc7kinetochore protein Spc7 Affinity Capture-MSPMID:16079914
mis12kinetochore protein Mis12 Affinity Capture-MSPMID:16079914
nuf2spindle pole body protein Nuf2 Affinity Capture-MSPMID:16079914
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External References
Database Identifier Description
NBRP SPAC29E6.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC29E6.04 Retrieval of eukaryotic orthologs
BioGrid SPAC29E6.04 BioGRID Interaction Datasets
Bähler Lab SPAC29E6.04 Cell Cycle Expression Profile
Bähler Lab SPAC29E6.04 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC29E6.04 Pheromone response/mating expression profiles
Bähler Lab SPAC29E6.04 Environmental stress expression profiles
Bähler Lab SPAC29E6.04 Bähler Lab Transcriptome Viewer
Cyclebase SPAC29E6.04 Cell Cycle Data
PInt SPAC29E6.04 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC29E6.04 Entrez Gene
WikiGene2541667kinetochore protein Nnf1
Uniprot_genenameNNF1
EntrezGene2541667kinetochore protein Nnf1
UniProtKB/SwissProtQ09858Kinetochore protein nnf1
ModBaseQ09858Database of comparative protein structure models
Pfam Protein DomainsQ09858Pfam Domain Arrangement
RefSeq PeptideNP_594562kinetochore protein Nnf1
RefSeq mRNANM_001019991972h- kinetochore protein Nnf1 (nnf1), mRNA
European Nucleotide ArchiveCAA91426ENA Protein Mapping
European Nucleotide ArchiveCAB66467ENA Protein Mapping
SPD / RIKEN03/03G04Orfeome Localization Data

Literature for nnf1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013