SPAC2C4.06c

Gene Standard NameUnassigned ChromosomeI
Systematic IDSPAC2C4.06c Gene Start4270937
Synonyms Gene End4269109
ProducttRNA (cytosine-5-)-methyltransferase (predicted) Gene Length1829
Feature Typeprotein coding CDS Start4270871
Name Description CDS End4269367
Characterisation Statusbiological_role_inferred CDS Length1505

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPAC2C4.06cdelta (deletion)deletionPMID:20473289
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0008168methyltransferase activityIEAUniProtKB:KW-0489GO_REF:0000037
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
GO:0030488tRNA methylationICGO:0008649GO_REF:0000001
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005730nucleolusIDAPMID:16823372
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
142709374270736
242706744270616
342705544269109

References

Region Start End Reference
three_prime_UTR42693664269109PMID:21511999
five_prime_UTR42709374270872PMID:21511999
three_prime_UTR42693664269109PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01189 IPR001678 Pfam Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p 124 419 4
G3DSA:3.40.50.150 Gene3D 199 419 65
SSF53335 SuperFamily 129 420 68
PR02008 IPR023267 PRINTS RNA (C5-cytosine) methyltransferase 404 421 4
PR02008 IPR023267 PRINTS RNA (C5-cytosine) methyltransferase 189 203 4
PR02008 IPR023267 PRINTS RNA (C5-cytosine) methyltransferase 288 300 4
PR02008 IPR023267 PRINTS RNA (C5-cytosine) methyltransferase 342 358 4
PR02008 IPR023267 PRINTS RNA (C5-cytosine) methyltransferase 220 230 4
PTHR22807 hmmpanther 1 460 2
PTHR22807:SF4 hmmpanther 1 460 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.78 Da
Charge 22.00
Isoelectric point 9.21
Molecular weight 51.88 kDa
Number of residues 460
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide2304.11PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide0.33PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide1.1PMID:23101633
Warning
DescriptionQualifierReference
gene structure updated PMID:21511999
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:21504829
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
SPAC1A6.03cphospholipase (predicted) Positive GeneticPMID:22681890
mug80cyclin Clg1 (predicted) Positive GeneticPMID:22681890
set1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
fft3fun thirty related protein Fft3 Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC2C4.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC2C4.06c Retrieval of eukaryotic orthologs
BioGrid SPAC2C4.06c BioGRID Interaction Datasets
Bähler Lab SPAC2C4.06c Cell Cycle Expression Profile
Bähler Lab SPAC2C4.06c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC2C4.06c Pheromone response/mating expression profiles
Bähler Lab SPAC2C4.06c Environmental stress expression profiles
Bähler Lab SPAC2C4.06c Bähler Lab Transcriptome Viewer
Cyclebase SPAC2C4.06c Cell Cycle Data
PInt SPAC2C4.06c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC2C4.06c Entrez Gene
WikiGene2542630rRNA methyltransferase (predicted)
EntrezGene2542630rRNA methyltransferase (predicted)
SPD / RIKEN24/24D07Orfeome Localization Data
UniProtKB/SwissProtO14039Putative methyltransferase C2C4.06c
ModBaseO14039Database of comparative protein structure models
Pfam Protein DomainsO14039Pfam Domain Arrangement
RefSeq PeptideNP_594509rRNA methyltransferase (predicted)
RefSeq mRNANM_001019938972h- rRNA methyltransferase (predicted) (SPAC2C4.06c), mRNA
European Nucleotide ArchiveCAB16366ENA Protein Mapping
UniParcUPI000228F4C7UniProt Archive

Literature for SPAC2C4.06c

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013