SPAC2F3.16

Gene Standard NameUnassigned ChromosomeI
Systematic IDSPAC2F3.16 Gene Start3957085
Synonyms Gene End3959427
Productubiquitin-protein ligase E3 (predicted) Gene Length2343
Feature Typeprotein coding CDS Start3957143
Name Description CDS End3958606
Characterisation Statusbiological_role_inferred CDS Length1464

Ensembl Gene Location
  1. saf2
  2. SPNCRNA.239
  3. SPNCRNA.240
  4. lsk1
  5. SPAC2F3.16
  6. SPAC11G7.01
  7. pub1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPAC2F3.16delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004842ubiquitin-protein ligase activityISMPFAM:PF00097GO_REF:0000001
GO:0008270zinc ion bindingISMPFAM:PF00097GO_REF:0000001
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0016567protein ubiquitinationISMPFAM:PF00097GO_REF:0000001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
139570853957442
239575123957844
339579003958004
439580673959427

References

Region Start End Reference
three_prime_UTR39586073959427PMID:21511999
five_prime_UTR39570853957142PMID:21511999
three_prime_UTR39586073959427PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF13639 IPR001841 Pfam Zinc finger, RING-type 270 314 15
PF05495 IPR008913 Pfam Zinc finger, CHY-type 142 216 4
SM00184 IPR001841 SMART Zinc finger, RING-type 271 312 50
PS51270 IPR017921 Prosite Profiles Zinc finger, CTCHY-type 204 270 1
PS50089 IPR001841 Prosite Profiles Zinc finger, RING-type 271 312 44
PS51266 IPR008913 Prosite Profiles Zinc finger, CHY-type 135 202 4
G3DSA:2.20.28.10 IPR004039 Gene3D 342 382 3
G3DSA:3.30.40.10 IPR013083 Gene3D 267 312 84
SSF161219 SuperFamily 135 203 4
SSF57850 SuperFamily 269 320 59
SSF161245 SuperFamily 205 264 1
PTHR21319 hmmpanther 15 410 1

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000153zf-C2H2 typeTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000153
PBO:0000173zf-C3HC4 type (RING finger)Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000173
PBO:0000176ubiquitin-protein ligase E3Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000176
PBO:0002306zf-CHYTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0002306
PBO:0002307LIM domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0002307

Protein Properties

Ave. residue weight 117.42 Da
Charge -4.50
Isoelectric point 6.10
Molecular weight 49.90 kDa
Number of residues 425
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide567.39PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2.9PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
cho1phosphatidyl-N-methylethanolamine N-methyltransferase (predicted) Negative GeneticPMID:22681890
def1RNAPII degradation factor Def1 (predicted) Positive GeneticPMID:22681890
SPAC27D7.06electron transfer flavoprotein alpha subunit (predicted) Negative GeneticPMID:22681890
pmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:22681890
liz1pantothenate transporter Liz1 Negative GeneticPMID:22681890
erp2COPII-coated vesicle component Erp2/3/4 (predicted) Negative GeneticPMID:22681890
SPAC9E9.09caldehyde dehydrogenase (predicted) Negative GeneticPMID:22681890
atf21transcription factor, Atf-CREB family Atf21 Negative GeneticPMID:22681890
vht1vitamin H transporter Vth1 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
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External References
Database Identifier Description
NBRP SPAC2F3.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC2F3.16 Retrieval of eukaryotic orthologs
BioGrid SPAC2F3.16 BioGRID Interaction Datasets
Bähler Lab SPAC2F3.16 Cell Cycle Expression Profile
Bähler Lab SPAC2F3.16 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC2F3.16 Pheromone response/mating expression profiles
Bähler Lab SPAC2F3.16 Environmental stress expression profiles
Bähler Lab SPAC2F3.16 Bähler Lab Transcriptome Viewer
Cyclebase SPAC2F3.16 Cell Cycle Data
PInt SPAC2F3.16 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC2F3.16 Entrez Gene
WikiGene2541608ubiquitin-protein ligase E3 (predicted)
EntrezGene2541608ubiquitin-protein ligase E3 (predicted)
SPD / RIKEN44/44G06Orfeome Localization Data
UniProtKB/SwissProtO14099Uncharacterized RING finger protein C2F3.16
ModBaseO14099Database of comparative protein structure models
Pfam Protein DomainsO14099Pfam Domain Arrangement
RefSeq PeptideNP_594394ubiquitin-protein ligase E3 (predicted)
RefSeq mRNANM_001019817972h- ubiquitin-protein ligase E3 (predicted) (SPAC2F3.16), mRNA
European Nucleotide ArchiveCAB16270ENA Protein Mapping
UniParcUPI000006A5DAUniProt Archive

Literature for SPAC2F3.16
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013