SPAC323.03c


Gene Standard NameUnassigned Characterisation StatusSchizosaccharomyces specific protein, uncharacterized
Systematic IDSPAC323.03c Feature Typeprotein coding
Synonyms Name Description
ProductSchizosaccharomyces specific protein Product Size575aa, 66.19 kDa
Genomic Location Chromosome I, 3912648-3910535 (2114nt); CDS:3912604-3910740 (1865nt)

Ensembl Gene Location
GO Cellular Component
Term NameCount
cell division site313
Annotation ExtensionEvidenceWith/FromReference
cytoplasm4212
Annotation ExtensionEvidenceWith/FromReference
mitotic spindle271
Annotation ExtensionEvidenceWith/FromReference
mitotic spindle pole body220
Annotation ExtensionEvidenceWith/FromReference
nucleus2691
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
decreased cell population growth on glucose carbon sourceSPAC323.03cΔ320
increased viability in stationary phaseSPAC323.03cΔ61
resistance to caffeine and rapamycinSPAC323.03cΔ33
viable vegetative cell populationSPAC323.03cΔ3844

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologySPAC323.03cΔ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3912648..3912543, 3912500..3912017, 3911964..3911828, 3911784..3910535
Intron3912542..3912501, 3912016..3911965, 3911827..3911785
mRNA3912648..3910535
5' UTR3912648..3912605PMID:21511999
CDS3912604..3912543, 3912500..3912017, 3911964..3911828, 3911784..3910740
3' UTR3910739..3910535PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.12 Da
Charge 7.00
Codon Adaptation Index 0.39
Isoelectric point 7.63
Molecular weight 66.19 kDa
Number of residues 575
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPAC323.03c

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
129.59during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.65during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.24during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
Schizosaccharomyces specific225
Orthologs

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC323.03c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds activation domain construct withSPAC323.03cSchizosaccharomyces specific protein Two-hybridPMID:26771498
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPAC323.03c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withelp6elongator complex subunit Elp6 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withvph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Positive GeneticPMID:18818364
positive genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Positive GeneticPMID:18818364
positive genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Positive GeneticPMID:18818364
positive genetic interaction withelp1elongator subunit Elp1 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withrsc1RSC complex subunit Rsc1 Positive GeneticPMID:18818364
positive genetic interaction withryh1GTPase Ryh1 Positive GeneticPMID:18818364
positive genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:18818364
positive genetic interaction withask1DASH complex subunit Ask1 Positive GeneticPMID:18818364
positive genetic interaction withmug154conserved fungal protein Positive GeneticPMID:18818364
positive genetic interaction withmed20mediator complex subunit Med20 Positive GeneticPMID:18818364
negative genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:18818364
negative genetic interaction withSPBC1861.07elongin C (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsgf29SAGA complex subunit Sgf29 Negative GeneticPMID:18818364
negative genetic interaction withmcs2TFIIH complex cyclin Mcs2 Negative GeneticPMID:22681890
negative genetic interaction withcuf2middle-meiotic transcription factor Cuf2 Negative GeneticPMID:22681890
negative genetic interaction withsyj1inositol-polyphosphate 5-phosphatase (synaptojanin homolog 1) Negative GeneticPMID:18818364
negative genetic interaction withfhl1forkhead transcription factor Fhl1 Negative GeneticPMID:22681890
negative genetic interaction withppk14serine/threonine protein kinase Ppk14 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsrb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:18818364
negative genetic interaction withpar1protein phosphatase PP2A regulatory subunit B-56 Par1 Negative GeneticPMID:22681890
negative genetic interaction withmid1medial ring protein Mid1 Negative GeneticPMID:22681890
negative genetic interaction withkin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
negative genetic interaction withser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction witheif21translation initiation factor eIF2A (predicted) Negative GeneticPMID:22681890
negative genetic interaction withamo1nuclear rim protein Amo1 Negative GeneticPMID:18818364
negative genetic interaction withSPBC15C4.06cubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmed13mediator complex subunit Med13 Negative GeneticPMID:18818364
negative genetic interaction withurk1uridine kinase/uracil phosphoribosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withngg1SAGA complex subunit Ngg1 Negative GeneticPMID:18818364
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:18818364
External References
Database Identifier Description
NBRP SPAC323.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC323.03c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC323.03c BioGRID Interaction Datasets
Expression Viewer SPAC323.03c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC323.03c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC323.03c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC323.03c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC323.03c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC323.03c Transcriptome Viewer (Bähler Lab)
GEO SPAC323.03c GEO profiles
PInt SPAC323.03c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC323.03c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC323.03c Fission yeast phenotypic data & analysis
Cyclebase SPAC323.03c.1 Cell Cycle Data
SPD / RIKEN26/26C09Orfeome Localization Data
UniProtKB/SwissProtQ9UT96Uncharacterized protein C323.03c
ModBaseQ9UT96Database of comparative protein structure models
STRINGQ9UT96Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594373sequence orphan
RefSeq mRNANM_001019794972h- sequence orphan (SPAC323.03c), mRNA
European Nucleotide ArchiveCAB53406.1ENA Protein Mapping
UniParcUPI000006C611UniProt Archive

Literature for SPAC323.03c

Search: Europe PMC or PubMed

Release Version: PomBase:30_60 - 12 May 2016