cam1 (SPAC3A12.14)

Gene Standard Namecam1 ChromosomeI
Systematic IDSPAC3A12.14 Gene Start1444658
Synonyms Gene End1446333
Productcalmodulin Cam1 Gene Length1676
Feature Typeprotein coding CDS Start1444930
Name Description CDS End1445508
Characterisation Statuspublished CDS Length579

Ensembl Gene Location
  1. SPNCRNA.741
  2. rpl2001
  3. cwf2
  4. atp11
  5. SPAC3A12.13c
  6. cam1
  7. vps53
  8. SPATRNAPRO.03
  9. tim17
  10. snR96
  11. cys12
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000121abnormal sporulationno_name (unrecorded)unrecordedPMID:2690071
FYPO:0000141abnormal mitotic sister chromatid segregationno_name (unrecorded)unrecordedPMID:9264467
FYPO:0000316inviable after spore germinationMicroscopycam1delta (deletion)deletionPECO:0000137PMID:3035538
FYPO:0001461normal immediate intracellular calcium spike following extracellular calcium stimulusSubstance quantificationcam1-1 (unknown)unknownNot specifiedPMID:21811607
FYPO:0002061inviable vegetative cell populationno_name (unrecorded)unrecordedPMID:9264467
Microscopycam1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005509calcium ion bindingIDAPMID:7657644
GO:0005515protein bindingIPImyo1PMID:11260263
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0030437ascospore formationIMPPMID:2690071
GO:0031322ascospore-type prospore-specific spindle pole body remodelingIMPPMID:20833892
GO:0033047regulation of mitotic sister chromatid segregation
requiredIMPPMID:9264467
GO:0071990maintenance of protein location in spindle pole body
has_input spo15IMPPMID:20833892
GO:0090307spindle assembly involved in mitosisIMPPMID:9264467
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005816spindle pole bodyIDAPMID:9264467
exists_during ascospore formationIDAPMID:20833892
GO:0005829cytosolIDAPMID:16823372
GO:0030427site of polarized growthIDAPMID:9264467
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
114446581444932
214450591446333

References

Region Start End Reference
three_prime_UTR14455091446333PMID:21511999
three_prime_UTR14455091446333PMID:21511999
five_prime_UTR14446581444929PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00036 IPR018248 Pfam EF-hand domain 49 76 7
PF00036 IPR018248 Pfam EF-hand domain 86 114 7
PF00036 IPR018248 Pfam EF-hand domain 122 148 7
PF00036 IPR018248 Pfam EF-hand domain 13 41 7
SM00054 IPR002048 SMART EF-hand domain 13 41 14
SM00054 IPR002048 SMART EF-hand domain 86 114 14
SM00054 IPR002048 SMART EF-hand domain 49 77 14
SM00054 IPR002048 SMART EF-hand domain 122 150 14
PS50222 IPR018249 Prosite Profiles EF-hand domain 9 44 20
PS50222 IPR018249 Prosite Profiles EF-hand domain 118 150 20
PS50222 IPR018249 Prosite Profiles EF-hand domain 82 117 20
PS50222 IPR018249 Prosite Profiles EF-hand domain 45 80 20
PS00018 IPR018247 Prosite Patterns EF-hand domain 95 107 12
PS00018 IPR018247 Prosite Patterns EF-hand domain 22 34 12
PS00018 IPR018247 Prosite Patterns EF-hand domain 58 70 12
PS00018 IPR018247 Prosite Patterns EF-hand domain 131 143 12
G3DSA:1.10.238.10 IPR011992 Gene3D 5 70 20
G3DSA:1.10.238.10 IPR011992 Gene3D 71 148 20
SSF47473 SuperFamily 3 147 21
PTHR23050 hmmpanther 1 150 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000276EF handTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000276
PBO:0000979calmodulin familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000979

Protein Properties

Ave. residue weight 112.70 Da
Charge -20.50
Isoelectric point 3.90
Molecular weight 16.91 kDa
Number of residues 150
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide25597.96PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide39964.3PMID:23101633
RNA level
experimental evidencePECO:0000014,
PECO:0000005		population_wide8.9PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
spo15sporulation protein Spo15 Phenotypic SuppressionPMID:20833892
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
mob1Sid2-Mob1 kinase complex regulatory subunit Mob1 Reconstituted ComplexPMID:15004232
spo15sporulation protein Spo15 Co-localizationPMID:20833892
pcp1pericentrin Pcp1 Reconstituted ComplexPMID:15004232
Reconstituted ComplexPMID:11864908
myo1myosin type I Affinity Capture-WesternPMID:11260263
rng2IQGAP Affinity Capture-WesternPMID:9635188
spo13sporulation specific guanyl-nucleotide exchange factor Spo13 Co-localizationPMID:20833892
lrp1leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
spo2sporulation specific protein Spo2 Co-localizationPMID:20833892
myo52myosin type V Two-hybridPMID:18003699
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
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External References
Database Identifier Description
NBRP SPAC3A12.14 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3A12.14 Retrieval of eukaryotic orthologs
BioGrid SPAC3A12.14 BioGRID Interaction Datasets
Bähler Lab SPAC3A12.14 Cell Cycle Expression Profile
Bähler Lab SPAC3A12.14 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC3A12.14 Pheromone response/mating expression profiles
Bähler Lab SPAC3A12.14 Environmental stress expression profiles
Bähler Lab SPAC3A12.14 Bähler Lab Transcriptome Viewer
Cyclebase SPAC3A12.14 Cell Cycle Data
PInt SPAC3A12.14 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC3A12.14 Entrez Gene
WikiGene2543039calmodulin Cam1
Uniprot_genenameCAM1
EntrezGene2543039calmodulin Cam1
UniProtKB/SwissProtP05933Calmodulin
ModBaseP05933Database of comparative protein structure models
Pfam Protein DomainsP05933Pfam Domain Arrangement
RefSeq PeptideNP_593340calmodulin Cam1
RefSeq mRNANM_001018772972h- calmodulin Cam1 (cam1), mRNA
European Nucleotide ArchiveAAA35291ENA Protein Mapping
European Nucleotide ArchiveCAB08742ENA Protein Mapping
SPD / RIKEN06/06C03Orfeome Localization Data
UniParcUPI0000126E6AUniProt Archive

Literature for cam1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013