rad55 (SPAC3C7.03c)

Gene Standard Namerad55 ChromosomeI
Systematic IDSPAC3C7.03c Gene Start2067904
Synonymsrhp55 Gene End2066442
ProductRecA family ATPase Rad55/Rhp55 Gene Length1463
Feature Typeprotein coding CDS Start2067764
Name Description CDS End2066668
Characterisation Statuspublished CDS Length1097

Ensembl Gene Location
  1. SPAC732.02c
  2. SPAC3C7.01c
  3. pil2
  4. SPNCRNA.791
  5. rad55
  6. SPAC3C7.04
  7. mug191
  8. pit1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000062abnormal nuclear morphologyno_name (unrecorded)unrecordedPMID:10430583
FYPO:0000089sensitive to methyl methanesulfonateno_name (unrecorded)unrecordedPMID:10430583
FYPO:0000158DNA content increasedno_name (unrecorded)unrecordedPMID:10430583
FYPO:0000267sensitive to ionizing radiationno_name (unrecorded)unrecordedPMID:10430583
FYPO:0000268sensitive to UVno_name (unrecorded)unrecordedPMID:10430583
FYPO:0002060viable vegetative cell populationMicroscopyrad55delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003697single-stranded DNA bindingIEAIPR013765GO_REF:0000002
GO:0005524ATP bindingISMIPR001553GO_REF:0000001
GO:0008094DNA-dependent ATPase activityISMIPR001553GO_REF:0000001
GO:0033170protein-DNA loading ATPase activityTASPMID:17353272
GO:0046982protein heterodimerization activityIPIrad57PMID:11560889
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000709meiotic joint molecule formationTASPMID:15466419
GO:0000724double-strand break repair via homologous recombinationIGIrad54PMID:15336631
GO:0000725recombinational repairIMPPMID:10430583
GO:0000730DNA recombinase assemblyNASGO_REF:0000001
GO:0006311meiotic gene conversion
requiredIMPPMID:12628934
GO:0006974response to DNA damage stimulusIMPPMID:10430583
GO:0006997nucleus organizationIMPPMID:10430583
GO:0007131reciprocal meiotic recombinationIMPPMID:14668362
GO:0009432SOS responseIEAIPR013765GO_REF:0000002
GO:0042148strand invasionTASPMID:17353272
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0033062Rhp55-Rhp57 complexNASGO_REF:0000001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
120679042067749
220677042066442
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00154 IPR013765 Pfam DNA recombination and repair protein RecA 29 80 1
PS50162 IPR020588 Prosite Profiles DNA recombination/repair protein RecA/RadB, ATP-binding domain 29 253 4
G3DSA:3.40.50.300 Gene3D 214 331 279
G3DSA:3.40.50.300 Gene3D 29 160 279
SSF52540 SuperFamily 25 170 294
PTHR13682 hmmpanther 1 343 1
PTHR13682:SF3 hmmpanther 1 343 1

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000539AAA family ATPaseTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000539
PBO:0001319RecA familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001319
PBO:0001320helix-hairpin-helixTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001320

Protein Properties

Ave. residue weight 111.42 Da
Charge 6.50
Isoelectric point 8.44
Molecular weight 39.00 kDa
Number of residues 350
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.3PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
srs2ATP-dependent DNA helicase, UvrD subfamily Synthetic RescuePMID:14993467
Synthetic Growth Defect
Synthetic RescuePMID:16135800
snz1pyridoxine biosynthesis protein Positive GeneticPMID:22681890
rad13DNA repair nuclease Rad13 Negative GeneticPMID:22681890
SPAC637.06alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
fsv1SNARE Fsv1 Negative GeneticPMID:22681890
pli1SUMO E3 ligase Pli1 Negative GeneticPMID:22681890
SPCC553.01cmeiotic chromosome segregation protein (predicted) Positive GeneticPMID:22681890
SPBC28F2.08cHRD ubiquitin ligase complex subunit (predicted) Negative GeneticPMID:22681890
atb2tubulin alpha 2 Negative GeneticPMID:22681890
SPBC1105.08EMP70 family Positive GeneticPMID:22681890
mst2histone acetyltransferase Mst2 Synthetic Growth DefectPMID:22184112
rap1telomere binding protein Rap1 Negative GeneticPMID:22681890
cgi121EKC/KEOPS complex subunit Cgi121 (predicted) Positive GeneticPMID:22681890
clr3histone deacetylase (class II) Clr3 Negative GeneticPMID:22681890
mcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
ppt1para-hydroxybenzoate--polyprenyltransferase Ppt1 Phenotypic EnhancementPMID:23365689
mug2cell surface glycoprotein, adhesion molecule (predicted), DUF1773 family protein 1 Negative GeneticPMID:22681890
rad8ubiquitin-protein ligase E3 Rad8 Phenotypic EnhancementPMID:19547744
Negative GeneticPMID:22681890
dad5DASH complex subunit Dad5 Synthetic Growth DefectPMID:23365689
Phenotypic Enhancement
rpl210260S ribosomal protein L21 (predicted) Negative GeneticPMID:22681890
slx8SUMO-targeted ubiquitin-protein ligase E3 Slx8 (predicted) Synthetic LethalityPMID:17762865
ubc13ubiquitin conjugating enzyme Ubc13 Negative GeneticPMID:22681890
ccq1telomere maintenance protein Ccq1 Negative GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
dep1Sds3-like family protein Dep1 Negative GeneticPMID:22681890
SPBC17A3.06phosphoprotein phosphatase (predicted) Positive GeneticPMID:22681890
amk2AMP-activated protein kinase beta subunit Amk2 Positive GeneticPMID:22681890
def1RNAPII degradation factor Def1 (predicted) Negative GeneticPMID:22681890
SPBC543.05cHC03 family inorganic anion exchanger (predicted) Positive GeneticPMID:22681890
rcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Negative GeneticPMID:22681890
rhp16Rad16 homolog Rhp16 Synthetic Growth DefectPMID:12675805
nth1DNA endonuclease III Synthetic Growth DefectPMID:12675805
Negative GeneticPMID:22681890
SPBC31F10.02acyl-CoA hydrolase (predicted) Negative GeneticPMID:22681890
gpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
SPBC9B6.11cCCR4/nocturin family endoribonuclease (predicted) Positive GeneticPMID:22681890
SPAC24B11.05pyrimidine 5'-nucleotidase (predicted) Negative GeneticPMID:22681890
SPAC30.02celongator complex associated protein Kti2 (predicted) Negative GeneticPMID:22681890
nup132nucleoporin Nup132 Negative GeneticPMID:22681890
cda1chitin deacetylase Cda1 Negative GeneticPMID:22681890
mag1DNA-3-methyladenine glycosylase Mag1 Synthetic RescuePMID:15722486
SPAC6G10.06FAD-dependent amino acid oxidase involved in late endosome to Golgi transport (predicted) Negative GeneticPMID:22681890
qcr6ubiquinol-cytochrome-c reductase complex subunit 8, hinge protein (predicted) Negative GeneticPMID:22681890
dad3DASH complex subunit Dad3 Phenotypic EnhancementPMID:23365689
Synthetic Growth Defect
swd3WD repeat protein Swd3 Negative GeneticPMID:22681890
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
klp5kinesin-like protein Klp5 Negative GeneticPMID:22681890
swi5Swi5 protein Synthetic Growth DefectPMID:15466419
SPBC13E7.07sequence orphan Negative GeneticPMID:22681890
raf2Rik1-associated factor Raf2 Negative GeneticPMID:22681890
rrp2ATP-dependent DNA helicase (predicted) Negative GeneticPMID:22681890
atg5autophagy associated protein Atg5 Negative GeneticPMID:22681890
SPCC1393.09cRWD domain protein, implicated in translation Negative GeneticPMID:22681890
rps120140S ribosomal protein S12 (predicted) Negative GeneticPMID:22681890
nup60nucleoporin Nup60 Negative GeneticPMID:22681890
SPAC869.03curea transporter (predicted) Negative GeneticPMID:22681890
hrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:22681890
pku80Ku domain protein Pku80 Positive GeneticPMID:22681890
SPCC777.02transcription factor (predicted) Negative GeneticPMID:22681890
pmd1leptomycin efflux transporter Pmd1 Phenotypic EnhancementPMID:23365689
hus1checkpoint clamp complex protein Hus1 Negative GeneticPMID:22681890
ams2cell cycle regulated GATA-type transcription factor Ams2 Positive GeneticPMID:22681890
SPBC21B10.08csequence orphan Negative GeneticPMID:22681890
rdp1RNA-directed RNA polymerase Rdp1 Negative GeneticPMID:22681890
rev3DNA polymerase zeta catalytic subunit Rev3 (predicted) Negative GeneticPMID:22681890
tma20RNA-binding protein Tma20 (predicted) Positive GeneticPMID:22681890
nse6Smc5-6 complex non-SMC subunit Nse6 Synthetic Growth DefectPMID:16478984
Synthetic Rescue
top3DNA topoisomerase III Synthetic RescuePMID:12724426
raf1Rik1-associated factor Raf1 Negative GeneticPMID:22681890
pom152nucleoporin Pom152 Negative GeneticPMID:22681890
ath1ataxin-2 homolog Negative GeneticPMID:22681890
trs130TRAPP complex subunit Trs130 (predicted) Negative GeneticPMID:22681890
SPCC338.14adenosine kinase (predicted) Negative GeneticPMID:22681890
rpb9DNA-directed RNA polymerase II complex subunit Rpb9 Positive GeneticPMID:22681890
dph1UBA domain protein Dph1 Negative GeneticPMID:22681890
gpd1glycerol-3-phosphate dehydrogenase Gpd1 Negative GeneticPMID:22681890
fma1methionine aminopeptidase Fma1 (predicted) Negative GeneticPMID:22681890
crb2DNA repair protein Rad9 homolog, Rhp9 Negative GeneticPMID:22681890
mrt4mRNA turnover and ribosome assembly protein Mrt4 (predicted) Negative GeneticPMID:22681890
SPAC5H10.04NADPH dehydrogenase (predicted) Negative GeneticPMID:22681890
rad3ATR checkpoint kinase Rad3 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:17178839
csn71COP9/signalosome complex subunit 7a (predicted) Positive GeneticPMID:22681890
pmt3SUMO Negative GeneticPMID:22681890
SPCC550.07acetamidase (predicted) Negative GeneticPMID:22681890
pcf2CAF assembly factor (CAF-1) complex subunit B, Pcf2 Negative GeneticPMID:22681890
fbh1DNA helicase I Synthetic RescuePMID:16135800
rqh1RecQ type DNA helicase Rqh1 Synthetic RescuePMID:14993467
Synthetic RescuePMID:16135800
Synthetic RescuePMID:15802523
ubp2ubiquitin C-terminal hydrolase Ubp2 Negative GeneticPMID:22681890
swi6HP1 family chromodomain protein Swi6 Negative GeneticPMID:22681890
SPBC83.17transcriptional coactivator, multiprotein bridging factor Mbf1 (predicted) Positive GeneticPMID:22681890
rad22DNA recombination protein Rad22 (previously Rad52) Synthetic Growth DefectPMID:10430583
ssb3DNA replication factor A subunit Ssb3 Synthetic Growth DefectPMID:20885790
SPCC2H8.05csequence orphan Negative GeneticPMID:22681890
rad2FEN-1 endonuclease Rad2 Negative GeneticPMID:22681890
rad17RFC related checkpoint protein Rad17 Negative GeneticPMID:22681890
mto1MT organizer Mto1 Negative GeneticPMID:22681890
SPAC6G9.14RNA-binding protein (predicted) Negative GeneticPMID:22681890
SPAC3H5.08cWD repeat protein, human WDR44 family Negative GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
pdh1DUF1751 family protein Negative GeneticPMID:22681890
myo51myosin type V Negative GeneticPMID:22681890
rpl35b60S ribosomal protein L35a (predicted) Negative GeneticPMID:22681890
gtb1gamma-tubulin Gtb1 Synthetic Growth DefectPMID:22737087
SPCC594.04csteroid oxidoreductase superfamily protein (predicted) Negative GeneticPMID:22681890
nem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
rav1RAVE complex subunit Rav1 Phenotypic EnhancementPMID:23365689
Synthetic Growth Defect
SPBC2G5.01ER protein involved in ER-nucleus signaling (predicted) Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
lub1WD repeat protein Lub1 Negative GeneticPMID:22681890
rpp20160S acidic ribosomal protein P2A subunit (predicted) Negative GeneticPMID:22681890
bun62WD repeat protein, human WDR20 family, Bun62 Negative GeneticPMID:22681890
rpl270160S ribosomal protein L27 Negative GeneticPMID:22681890
upf1ATP-dependent RNA helicase Upf1 Negative GeneticPMID:22681890
egd2nascent polypeptide-associated complex alpha subunit Egd2 Negative GeneticPMID:22681890
SPBPB10D8.06cmembrane transporter (predicted) Negative GeneticPMID:22681890
gcd10tRNA (m1A) methyltransferase, translation initiation factor eIF-3 gamma subunit Gcd10 (predicted) Negative GeneticPMID:22681890
ubp6ubiquitin C-terminal hydrolase Ubp6 Negative GeneticPMID:22681890
atl1alkyltransferase-like protein Atl1 Negative GeneticPMID:22681890
SPBC56F2.03actin-like protein Arp10 (predicted) Negative GeneticPMID:22681890
mad2spindle checkpoint protein Mad2 Synthetic Growth DefectPMID:22737087
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:22681890
SPBC651.12csequence orphan Positive GeneticPMID:22681890
clr2chromatin silencing protein Clr2 Negative GeneticPMID:22681890
rec11meiotic cohesin complex subunit Rec11 Negative GeneticPMID:22681890
hrq1RecQ type DNA helicase Hrq1 (predicted) Negative GeneticPMID:22681890
SPAC9E9.09caldehyde dehydrogenase (predicted) Negative GeneticPMID:22681890
ubp4ubiquitin C-terminal hydrolase Ubp4 Negative GeneticPMID:22681890
adn2transcription factor (predicted) Negative GeneticPMID:22681890
ssp2serine/threonine protein kinase Ssp2 Positive GeneticPMID:22681890
air1zinc knuckle TRAMP complex subunit Air1 Positive GeneticPMID:22681890
atg1autophagy and CVT pathway serine/threonine protein kinase Atg1 Positive GeneticPMID:22681890
mug51variant protein kinase 19 family protein Negative GeneticPMID:22681890
zip1transcription factor Zip1 Positive GeneticPMID:22681890
apt1adenine phosphoribosyltransferase (APRT) (predicted) Negative GeneticPMID:22681890
sfr1Swi five-dependent recombination repair protein Sfr1 Phenotypic EnhancementPMID:18769921
Phenotypic SuppressionPMID:16080597
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative GeneticPMID:22681890
SPBC1778.09GTPase activating protein (predicted) Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
pac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
rhp18Rad18 homolog Rhp18 Negative GeneticPMID:22681890
set9histone lysine methyltransferase Set9 Negative GeneticPMID:22681890
vac7Vac7 ortholog (predicted) Negative GeneticPMID:22681890
ura1carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1 Negative GeneticPMID:22681890
rad50DNA repair protein Rad50 Phenotypic EnhancementPMID:11726502
SPBC25H2.15SSU-rRNA maturation protein Tsr4 homolog 1 (predicted) Negative GeneticPMID:22681890
rpl100260S ribosomal protein L10 Negative GeneticPMID:22681890
SPBC3B8.04cmembrane transporter (predicted) Negative GeneticPMID:22681890
SPBC1289.14adducin (predicted) Negative GeneticPMID:22681890
cho2phosphatidylethanolamine N-methyltransferase Cho2 Negative GeneticPMID:22681890
sum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Synthetic Growth DefectPMID:22184112
rpl10260S ribosomal protein L10a Negative GeneticPMID:22681890
rad1checkpoint clamp complex protein Rad1 Negative GeneticPMID:22681890
rhp23Rad23 homolog Rhp23 Negative GeneticPMID:22681890
mms19Dos2 silencing complex subunit Mms19 Positive GeneticPMID:22681890
dis323'-5'-exoribonuclease activity Dis3L2 Negative GeneticPMID:22681890
rsc4RSC complex subunit Rsc4 Negative GeneticPMID:22681890
otu2ubiquitin specific cysteine protease, OTU family, Otu2 Negative GeneticPMID:22681890
ubc14ubiquitin conjugating enzyme Ubc14 (predicted) Negative GeneticPMID:22681890
dmc1RecA family ATPase Dmc1 Phenotypic EnhancementPMID:14668362
SPAC750.01aldo/keto reductase family protein Negative GeneticPMID:22681890
rps40140S ribosomal protein S4 (predicted) Negative GeneticPMID:22681890
rik1silencing protein Rik1 Negative GeneticPMID:22681890
taz1human TRF ortholog Taz1 Negative GeneticPMID:22681890
gma12alpha-1,2-galactosyltransferase Gma12 Negative GeneticPMID:22681890
SPBC1198.06cmannan endo-1,6-alpha-mannosidase (predicted) Positive GeneticPMID:22681890
SPCC24B10.18human Leydig cell tumor 10 kDa protein homolog Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
rad51RecA family recombinase Rad51/Rhp51 Two-hybridPMID:11560889
rad57RecA family ATPase Rad57/Rhp57 Two-hybridPMID:11560889
Affinity Capture-Western
rad22DNA recombination protein Rad22 (previously Rad52) Two-hybridPMID:11560889
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External References
Database Identifier Description
NBRP SPAC3C7.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3C7.03c Retrieval of eukaryotic orthologs
BioGrid SPAC3C7.03c BioGRID Interaction Datasets
Bähler Lab SPAC3C7.03c Cell Cycle Expression Profile
Bähler Lab SPAC3C7.03c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC3C7.03c Pheromone response/mating expression profiles
Bähler Lab SPAC3C7.03c Environmental stress expression profiles
Bähler Lab SPAC3C7.03c Bähler Lab Transcriptome Viewer
Cyclebase SPAC3C7.03c Cell Cycle Data
PInt SPAC3C7.03c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC3C7.03c Entrez Gene
WikiGene2543685RecA family ATPase Rhp55
Uniprot_genenameRHP55
EntrezGene2543685RecA family ATPase Rhp55
SPD / RIKEN40/40C10Orfeome Localization Data
UniProtKB/SwissProtO14129DNA repair protein rhp55
ModBaseO14129Database of comparative protein structure models
Pfam Protein DomainsO14129Pfam Domain Arrangement
RefSeq PeptideNP_593604RecA family ATPase Rhp55
RefSeq mRNANM_001019035972h- RecA family ATPase Rhp55 (rhp55), mRNA
European Nucleotide ArchiveAAC17871ENA Protein Mapping
European Nucleotide ArchiveCAB16734ENA Protein Mapping
UniParcUPI0000133039UniProt Archive

Literature for rad55
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013