hrp3 (SPAC3G6.01)

Gene Standard Namehrp3 ChromosomeI
Systematic IDSPAC3G6.01 Gene Start5377829
Synonyms Gene End5382913
ProductATP-dependent DNA helicase Hrp3 Gene Length5085
Feature Typeprotein coding CDS Start5378427
Name DescriptionHelicase-Related protein from S. Pombe CDS End5382650
Characterisation Statuspublished CDS Length4224

Ensembl Gene Location
  1. dsc4
  2. new13
  3. fet5
  4. usp104
  5. hrp3
  6. dss1
  7. SPAC3G6.03c
  8. rnp24
  9. snoR69
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyhrp3delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:12127990
GO Molecular Function

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0003677DNA bindingIEAUniProtKB:KW-0238GO_REF:0000037
GO:0004003ATP-dependent DNA helicase activityIDAPMID:10756203
GO:0005515protein bindingIPInap1PMID:17510629
GO:0005524ATP bindingICGO:0004003GO_REF:0000001
GO:0008094DNA-dependent ATPase activityISMPFAM:PF00176GO_REF:0000001
GO Biological Process

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0000070mitotic sister chromatid segregationIMPPMID:15908586
GO:0006338chromatin remodelingNASGO_REF:0000051
GO:0030466chromatin silencing at silent mating-type cassetteIMPPMID:12127990
NOT GO:0030702chromatin silencing at centromereIMPPMID:12127990
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEPPMID:17510629
GO:0060303regulation of nucleosome densityIMPPMID:17510629
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0000790nuclear chromatinNASGO_REF:0000001
GO:0005634nucleusIDAPMID:16823372
GO:0031934mating-type region heterochromatinIDAPMID:12127990
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
153778295377926
253784225378618
353786765382913

References

Region Start End Reference
three_prime_UTR53826515382913PMID:21511999
five_prime_UTR53778295377926PMID:21511999
three_prime_UTR53826515382913PMID:21511999
five_prime_UTR53784225378426PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00176 IPR000330 Pfam SNF2-related 378 661 20
PF00271 IPR001650 Pfam Helicase, C-terminal 725 804 69
PF00385 IPR023780 Pfam Chromo domain/shadow 289 340 7
PF00385 IPR023780 Pfam Chromo domain/shadow 193 237 7
PF13907 IPR025260 Pfam Domain of unknown function DUF4208 1287 1387 1
SM00298 IPR000953 SMART Chromo domain/shadow 190 253 9
SM00298 IPR000953 SMART Chromo domain/shadow 286 342 9
SM00487 IPR014001 SMART Helicase, superfamily 1/2, ATP-binding domain 371 564 69
SM00490 IPR001650 SMART Helicase, C-terminal 720 804 67
PS00598 IPR023779 Prosite Patterns Chromo domain/shadow 216 236 4
PS51194 IPR001650 Prosite Profiles Helicase, C-terminal 694 852 69
PS51192 IPR014001 Prosite Profiles Helicase, superfamily 1/2, ATP-binding domain 387 557 69
PS50013 IPR000953 Prosite Profiles Chromo domain/shadow 191 260 7
PS50013 IPR000953 Prosite Profiles Chromo domain/shadow 288 349 7
G3DSA:3.40.50.300 Gene3D 373 541 279
G3DSA:2.40.50.40 Gene3D 283 343 7
G3DSA:2.40.50.40 Gene3D 185 237 7
G3DSA:3.40.50.300 Gene3D 686 832 279
SSF54160 IPR016197 SuperFamily 187 253 9
SSF52540 SuperFamily 594 890 294
SSF54160 IPR016197 SuperFamily 266 340 9
SSF52540 SuperFamily 359 592 294
PTHR10799 hmmpanther 105 1234 21
PTHR10799:SF70 hmmpanther 105 1234 2
Coil ncoils Rabaptin coiled-coil domain 270 291 974
Coil ncoils Rabaptin coiled-coil domain 935 963 974

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:18257517

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000174DEAD/DEAH box helicaseTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000174
PBO:0000175helicase C-terminal domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000175
PBO:0001050chromodomain proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001050

Protein Properties

Ave. residue weight 114.83 Da
Charge 4.00
Isoelectric point 6.74
Molecular weight 159.38 kDa
Number of residues 1388
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3061.23PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.73PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3.3PMID:23101633
Misc
DescriptionQualifierReference
targets correlated with Clr3 and Sir2 targets PMID:17510629
overlapping genome wide occupancy in coding regions Nap1/Hrp1/Hrp3 PMID:17510629
overlapping genome wide occupancy in promoters Nap1/Hrp1/Hrp3 PMID:17510629
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Contact Curators
Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:18818364
ctu1cytosolic thiouridylase subunit Ctu1 Negative GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Phenotypic EnhancementPMID:22990236
fsv1SNARE Fsv1 Positive GeneticPMID:22681890
sec72Sec7 domain protein, ARF GEF Sec72 Negative GeneticPMID:22681890
tpp1trehalose-6-phosphate phosphatase Tpp1 Negative GeneticPMID:22681890
sif3Sad1 interacting factor 3 (predicted) Positive GeneticPMID:22681890
mug2cell surface glycoprotein, adhesion molecule (predicted), DUF1773 family protein 1 Positive GeneticPMID:22681890
alg12dolichyl pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase Alg12 (predicted) Negative GeneticPMID:22681890
hta1histone H2A alpha Positive GeneticPMID:22681890
ase1antiparallel microtubule cross-linking factor Ase1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBPB2B2.18sequence orphan Positive GeneticPMID:22681890
snr13-hydroxyisobutyryl-CoA hydrolase snr1 Positive GeneticPMID:22681890
SPAC1705.02human 4F5S homolog Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mgr2mitochondrial membrane protein Mgr2 (predicted) Negative GeneticPMID:22681890
SPAC144.17c6-phosphofructo-2-kinase (predicted) Negative GeneticPMID:22681890
mrc1mediator of replication checkpoint 1 Negative GeneticPMID:18818364
obr1ubiquitinated histone-like protein Uhp1 Positive GeneticPMID:22681890
rex3exonuclease Rex3 (predicted) Positive GeneticPMID:22681890
SPCP1E11.10ankyrin repeat protein, unknown biological role Negative GeneticPMID:22681890
SPAC30D11.11Haemolysin-III family protein (predicted) Positive GeneticPMID:22681890
SPBC1703.11optic atrophy 3 family protein Positive GeneticPMID:22681890
gpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
cdc10MBF transcription factor complex subunit Cdc10 Negative GeneticPMID:22681890
SPCC1840.09NAD dependent epimerase/dehydratase family protein Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
wtf16wtf element Wtf16 Negative GeneticPMID:22681890
SPAC821.05translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
rpl430260S ribosomal protein L37a (predicted) Positive GeneticPMID:22681890
pob3FACT complex subunit Pob3 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
SPAC4H3.03cglucan 1,4-alpha-glucosidase (predicted) Negative GeneticPMID:22681890
coq10mitochondrial ubiquinone binding protein Coq10 Positive GeneticPMID:22681890
SPAC4A8.10lipase (predicted) Negative GeneticPMID:22681890
pck1protein kinase C (PKC)-like Pck1 Negative GeneticPMID:22681890
SPBC146.04sulfhydryl oxidase (predicted) Positive GeneticPMID:22681890
SPAC977.17MIP water channel (predicted) Negative GeneticPMID:22681890
cch1calcium channel Cch1 Negative GeneticPMID:22681890
epe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:18818364
ies4Ino80 complex subunit Ies4 Negative GeneticPMID:22681890
ppr8mitochondrial PPR repeat protein Ppr8 Negative GeneticPMID:22681890
mcs2TFIIH complex cyclin Mcs2 Negative GeneticPMID:22681890
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Negative GeneticPMID:18818364
SPAC5D6.04auxin family transmembrane transporter (predicted) Positive GeneticPMID:22681890
erg5C-22 sterol desaturase Erg5 Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
rps250240S ribosomal protein S25 (predicted) Positive GeneticPMID:22681890
rps100140S ribosomal protein S10 (predicted) Negative GeneticPMID:22681890
dbr1RNA lariat debranching enzyme Dbr1 Positive GeneticPMID:22681890
rsv2transcription factor Rsv2 Negative GeneticPMID:22681890
mbx1MADS-box transcription factor Mbx1 Positive GeneticPMID:22681890
trm10tRNA m(1)G methyltransferase Trm10 (predicted) Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
tma20RNA-binding protein Tma20 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
trs130TRAPP complex subunit Trs130 (predicted) Negative GeneticPMID:22681890
arz1armadillo repeat containing, Zfs1 target number 1 Positive GeneticPMID:22681890
SPAC4A8.14ribose-phosphate pyrophosphokinase (predicted) Positive GeneticPMID:22681890
moe1translation initiation factor eIF3d Moe1 Negative GeneticPMID:22681890
SPBC32F12.12cGolgi membrane protein involved in vesicle-mediated transport (predicted) Positive GeneticPMID:22681890
dsk1SR protein-specific kinase Dsk1 Positive GeneticPMID:22681890
ppa2serine/threonine protein phosphatase Ppa2 Negative GeneticPMID:22681890
SPAC694.02DEAD/DEAH box helicase Negative GeneticPMID:22681890
sdh3succinate dehydrogenase (ubiquinone) cytochrome b subunit (predicted) Positive GeneticPMID:22681890
SPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
pub1HECT-type ubiquitin-protein ligase E3 Pub1 Negative GeneticPMID:22681890
cho1phosphatidyl-N-methylethanolamine N-methyltransferase (predicted) Positive GeneticPMID:18818364
SPCC594.01DUF1769 family protein Negative GeneticPMID:22681890
kap114karyopherin Kap14 Positive GeneticPMID:22681890
spo15sporulation protein Spo15 Negative GeneticPMID:22681890
SPAC2F7.17mitochondrial peptide chain release factor (predicted) Negative GeneticPMID:22681890
sif2Sad1 interacting factor 2 (predicted) Positive GeneticPMID:22681890
ppm1leucine carboxyl methyltransferase Ppm1 (predicted) Negative GeneticPMID:22681890
sdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:18818364
set6histone lysine methyltransferase Set6 (predicted) Positive GeneticPMID:22681890
ctu2cytosolic thiouridylase subunit Ctu2 Negative GeneticPMID:22681890
SPAC3A12.06csodium/calcium exchanger (predicted) Positive GeneticPMID:22681890
dip1WISH/DIP/SPIN90 ortholog Dip1 Negative GeneticPMID:22681890
mug113T5orf172 family protein Negative GeneticPMID:22681890
omh6alpha-1,2-mannosyltransferase Omh6 (predicted) Negative GeneticPMID:22681890
spn3septin Spn3 Positive GeneticPMID:22681890
apq12nuclear membrane organization protein Apq12 (predicted) Negative GeneticPMID:22681890
SPAC1B3.02ctranscription elongation factor, Elf1 family (predicted) Negative GeneticPMID:22681890
SPBC1861.07elongin C (predicted) Negative GeneticPMID:18818364
SPCC16C4.20cHMG box protein (predicted) Negative GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
cwf7splicing factor Cwf7 Positive GeneticPMID:22681890
snd1RNA-binding protein Snd1 Positive GeneticPMID:22681890
SPAC3G9.05GTPase activating protein (predicted) Negative GeneticPMID:22681890
rpl230160S ribosomal protein L23 Positive GeneticPMID:22681890
pex1AAA family ATPase Pex1 (predicted) Positive GeneticPMID:22681890
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:18818364
rps40240S ribosomal protein S4 (predicted) Negative GeneticPMID:22681890
SPAC25B8.05tRNA-pseudouridine synthase (predicted) Positive GeneticPMID:18818364
php3CCAAT-binding factor complex subunit Php3 Negative GeneticPMID:22681890
rpp20160S acidic ribosomal protein P2A subunit (predicted) Positive GeneticPMID:22681890
bdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:22681890
SPAC3A11.07NADH dehydrogenase (predicted) Positive GeneticPMID:22681890
SPAC644.08methionine salvage haloacid dehalogenase-like hydrolase (predicted) Positive GeneticPMID:22681890
SPAC1486.01manganese superoxide dismutase (predicted) Positive GeneticPMID:22681890
syj1inositol-polyphosphate 5-phosphatase (synaptojanin homolog 1) Positive GeneticPMID:22681890
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Positive GeneticPMID:18818364
lys4homocitrate synthase Negative GeneticPMID:22681890
upf1ATP-dependent RNA helicase Upf1 Negative GeneticPMID:22681890
chp1chromodomain protein Chp1 Negative GeneticPMID:22681890
rxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
Phenotypic EnhancementPMID:19547744
nrm1negative regulator of MBF Negative GeneticPMID:22681890
SPCC663.15cconserved fungal protein Positive GeneticPMID:22681890
shg1Set1C complex subunit Shg1 Negative GeneticPMID:22681890
SPAC1002.12csuccinate-semialdehyde dehydrogenase Positive GeneticPMID:22681890
res2MBF transcription factor complex subunit Res2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
SPCC594.06cvacuolar SNARE Vam7 (predicted) Negative GeneticPMID:22681890
int6eIF3e subunit Int6 Negative GeneticPMID:22681890
ubp4ubiquitin C-terminal hydrolase Ubp4 Positive GeneticPMID:22681890
ubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Negative GeneticPMID:18818364
ulp1SUMO deconjugating enzyme Ulp1 Positive GeneticPMID:22681890
bst1GPI inositol deacylase Bst1 (predicted) Negative GeneticPMID:22681890
SPAPJ695.01cS. pombe specific UPF0321 family protein 3 Negative GeneticPMID:22681890
mex67mRNA export receptor, Tap, nucleoporin Mex67 Positive GeneticPMID:22681890
fft3fun thirty related protein Fft3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
tcg1single-stranded telomeric binding protein Tgc1 Positive GeneticPMID:22681890
swd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC227.06Rab GTPase binding (predicted) Negative GeneticPMID:22681890
msy2MS ion channel protein 2 (predicted) Positive GeneticPMID:22681890
SPAC2C4.09DUF1640 family protein Positive GeneticPMID:22681890
clr1cryptic loci regulator Clr1 Positive GeneticPMID:22681890
btb1BTB/POZ domain protein Btb1 Negative GeneticPMID:22681890
ebs1EST1 family nonsense-mediated mRNA decay (NMD) pathway protein Ebs1 (predicted) Negative GeneticPMID:18818364
abc2glutathione S-conjugate-exporting ATPase Abc2 Positive GeneticPMID:22681890
sec28coatomer epsilon subunit (predicted) Positive GeneticPMID:18818364
SPBC3E7.05chuman mitofilin ortholog (predicted) Positive GeneticPMID:22681890
mug20sequence orphan Negative GeneticPMID:22681890
dot2ESCRT II complex subunit Dot2 Positive GeneticPMID:18818364
SPCC18.17c26S proteasome non-ATPase regulatory subunit (predicted) Negative GeneticPMID:22681890
eme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
SPBC16D10.08cheat shock protein Hsp104 (predicted) Negative GeneticPMID:22681890
SPAC26A3.11amidohydrolase Positive GeneticPMID:22681890
mdm31mitochondrial inner membrane protein Mdm31 (predicted) Positive GeneticPMID:22681890
ada1adenosine deaminase Ada1 (predicted) Positive GeneticPMID:22681890
tea2kinesin-like protein Tea2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
oga1Stm1 homolog Oga1 Positive GeneticPMID:22681890
SPAC1610.01conserved eukaryotic protein Negative GeneticPMID:22681890
cwf21complexed with Cdc5 protein Cwf21 Negative GeneticPMID:18818364
SPBC8E4.03agmatinase 2 (predicted) Positive GeneticPMID:22681890
rtn1reticulon-like protein Rtn1 Negative GeneticPMID:22681890
SPBC25H2.03vacuolar protein involved in phosphoinositide metabolism (predicted) Negative GeneticPMID:22681890
shy1SURF-family protein Shy1 (predicted) Positive GeneticPMID:22681890
tip1CLIP170 family protein Tip1 Negative GeneticPMID:22681890
msy1MS ion channel protein 1 (predicted) Positive GeneticPMID:22681890
SPBC725.04oxalyl-CoA decarboxylase (predicted) Positive GeneticPMID:22681890
SPBC20F10.07GRAM domain protein Positive GeneticPMID:22681890
mst2histone acetyltransferase Mst2 Negative GeneticPMID:18818364
rap1telomere binding protein Rap1 Negative GeneticPMID:18818364
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
clr3histone deacetylase (class II) Clr3 Phenotypic EnhancementPMID:22990236
elp6elongator complex subunit Elp6 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
spf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dep1Sds3-like family protein Dep1 Negative GeneticPMID:22681890
SPCC1442.05cmitochondrial protein Positive GeneticPMID:22681890
reb1RNA polymerase I transcription termination factor Reb1 Negative GeneticPMID:18818364
SPBC17A3.06phosphoprotein phosphatase (predicted) Positive GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
SPBC31F10.02acyl-CoA hydrolase (predicted) Positive GeneticPMID:22681890
swc3Swr1 complex subunit Swc3 Positive GeneticPMID:18818364
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
swd2Set1C complex subunit Swd2.1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC36B7.08cnucleosome assembly protein (predicted) Positive GeneticPMID:18818364
SPAC24H6.13DUF221 family protein implicated in Golgi to plasma membrane transport (predicted) Negative GeneticPMID:22681890
whi5cell cycle transcriptional repressor Whi5 (predicted) Positive GeneticPMID:22681890
php5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
erg28Erg28 protein (predicted) Negative GeneticPMID:22681890
SPBC23E6.10cmethylthioribose-1-phosphate isomerase (predicted) Positive GeneticPMID:22681890
swd3WD repeat protein Swd3 Negative GeneticPMID:18818364
SPBC16C6.04sequence orphan Negative GeneticPMID:22681890
spo12Spo12 family protein Positive GeneticPMID:18818364
SPBC651.04sequence orphan Negative GeneticPMID:22681890
rsc1RSC complex subunit Rsc1 Negative GeneticPMID:18818364
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
SPCC4B3.13MatE family transporter (predicted) Positive GeneticPMID:22681890
SPCC1739.06curoporphyrin methyltransferase (predicted) Positive GeneticPMID:22681890
ef1a-atranslation elongation factor EF-1 alpha Ef1a-a Positive GeneticPMID:22681890
mca1transcription factor, zf-fungal binuclear cluster type (predicted) Negative GeneticPMID:22681890
rpl160160S ribosomal protein L13/L16 (predicted) Positive GeneticPMID:18818364
alf1ATP-dependent microtubule severing protein (predicted) Negative GeneticPMID:22681890
rpl90160S ribosomal protein L9 Positive GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
snf22ATP-dependent DNA helicase Snf22 Phenotypic EnhancementPMID:18199689
mug14adducin Negative GeneticPMID:22681890
SPBPB2B2.19cS. pombe specific 5Tm protein family Negative GeneticPMID:22681890
SPAC8C9.05D-Tyr-tRNA deacylase (predicted) Positive GeneticPMID:22681890
set2histone lysine methyltransferase Set2 Phenotypic EnhancementPMID:22990236
SPCC1442.02central kinetochore associated family protein (predicted) Negative GeneticPMID:22681890
SPCC794.01cglucose-6-phosphate 1-dehydrogenase (predicted) Positive GeneticPMID:22681890
SPBC4B4.04translation initiation factor eIF2A (predicted) Negative GeneticPMID:18818364
SPAC24B11.12cP-type ATPase (predicted) Negative GeneticPMID:22681890
SPCC162.06cvacuolar sorting protein Vps60 (predicted) Positive GeneticPMID:22681890
mug80cyclin Clg1 (predicted) Negative GeneticPMID:22681890
hht2histone H3 h3.2 Positive GeneticPMID:18818364
alg9mannosyltransferase complex subunit Alg9 (predicted) Negative GeneticPMID:22681890
ubx2UBX domain protein Ubx2 Positive GeneticPMID:22681890
SPAC6G9.01cconserved protein Negative GeneticPMID:22681890
rad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:22681890
SPCC550.07acetamidase (predicted) Positive GeneticPMID:22681890
pof9F-box protein Pof9 Positive GeneticPMID:18818364
SPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:22681890
fbh1DNA helicase I Positive GeneticPMID:18818364
liz1pantothenate transporter Liz1 Negative GeneticPMID:22681890
ssu72phosphoric ester hydrolase Ssu72 (predicted) Positive GeneticPMID:18818364
mal3EB1 family Mal3 Negative GeneticPMID:22681890
sol1SWI/SNF complex subunit Sol1 Negative GeneticPMID:22681890
mid1medial ring protein Mid1 Negative GeneticPMID:22681890
hob3BAR adaptor protein Hob3 Negative GeneticPMID:22681890
ash2Ash2-trithorax family protein Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
set1histone lysine methyltransferase Set1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCP20C8.02cS. pombe specific UPF0321 family protein 1 Negative GeneticPMID:22681890
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative GeneticPMID:18818364
lsg1Lsk1 complex gamma subunit (predicted) Positive GeneticPMID:22681890
SPBC8E4.05cfumarate lyase superfamily Negative GeneticPMID:22681890
fml2ATP-dependent 3' to 5' DNA helicase (predicted) Positive GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
atg6beclin family protein, involved in autophagy Positive GeneticPMID:22681890
SPAC18B11.03cN-acetyltransferase (predicted) Positive GeneticPMID:22681890
SPBC28E12.04sequence orphan Positive GeneticPMID:22681890
get1GET complex subunit Get1 (predicted) Positive GeneticPMID:22681890
sap114U2 snRNP subunit Sap114 Negative GeneticPMID:22681890
trx2mitochondrial thioredoxin Trx2 Positive GeneticPMID:22681890
dcd1deoxycytidylate deaminase (predicted) Negative GeneticPMID:22681890
mug178mitochondrial ribosomal protein subunit L51-b (predicted) Positive GeneticPMID:22681890
SPCC794.11cENTH/VHS domain protein Ent3 (predicted) Negative GeneticPMID:22681890
SPBC1271.09glycerophosphodiester transporter (predicted) Positive GeneticPMID:22681890
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
lon1Lon protease homolog Lon1 (predicted) Negative GeneticPMID:22681890
SPAC22H10.09sequence orphan Positive GeneticPMID:22681890
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
SPAC328.01ckaryopherin (predicted) Negative GeneticPMID:18818364
SPBC839.03cneddylation protein Dcn1 (predicted) Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC13E7.08cRNA polymerase II associated Paf1 complex (predicted) Positive GeneticPMID:22681890
rnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Positive GeneticPMID:18818364
ssr3SWI/SNF and RSC complex subunit Ssr3 Positive GeneticPMID:18818364
pom1DYRK family protein kinase Pom1 Negative GeneticPMID:18818364
ies2Ino80 complex subunit Ies2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
swi3replication fork protection complex subunit Swi3 Negative GeneticPMID:18818364
mak10NatC N-acetyltransferase complex subunit Mak10 (predicted) Positive GeneticPMID:22681890
SPAC3C7.01cinositol polyphosphate phosphatase (predicted) Positive GeneticPMID:22681890
apm3AP-3 adaptor complex subunit Apm3 (predicted) Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
Phenotypic EnhancementPMID:22990236
SPBC1348.03S. pombe specific 5Tm protein family Negative GeneticPMID:22681890
SPAPB21F2.02Dopey family protein (predicted) Positive GeneticPMID:22681890
SPAC824.09cGTPase activating protein (predicted) Negative GeneticPMID:22681890
med20mediator complex subunit Med20 Positive GeneticPMID:18818364
nup37WD repeat protein, nucleoporin Nup37 (predicted) Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC188.09ccell surface glycoprotein, adhesion molecule (predicted) Positive GeneticPMID:22681890
cwf16splicing factor Cwf16 Positive GeneticPMID:22681890
amo1nuclear rim protein Amo1 Positive GeneticPMID:18818364
nto1histone acetyltransferase complex subunit Nto1 (predicted) Negative GeneticPMID:22681890
ppk27serine/threonine protein kinase Ppk27 (predicted) Negative GeneticPMID:22681890
SPAC1399.04curacil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
scs7sphingosine hydroxylase Scs7 Negative GeneticPMID:18818364
rga8Rho-type GTPase activating protein Rga8 Negative GeneticPMID:22681890
SPBC16H5.12cconserved fungal protein Positive GeneticPMID:22681890
SPBC29A10.16ccytochrome b5 (predicted) Negative GeneticPMID:22681890
gms1UDP-galactose transporter Gms1 Negative GeneticPMID:22681890
plh1phospholipid-diacylglycerol acyltransferase Plh1 Negative GeneticPMID:22681890
SPCC1223.01ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:18818364
SPCC736.07cunconventional prefoldin involved in translation initiation (predicted) Positive GeneticPMID:22681890
srb11cyclin CycC, Srb mediator subunit Srb11 Positive GeneticPMID:18818364
nrc1bromodomain protein (predicted) Positive GeneticPMID:18818364
sgf29SAGA complex subunit Sgf29 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dis323'-5'-exoribonuclease activity Dis3L2 Positive GeneticPMID:22681890
mit1SHREC complex subunit Mit1 Synthetic LethalityPMID:23103765
SPBC646.08coxysterol binding protein (predicted) Positive GeneticPMID:22681890
rsc4RSC complex subunit Rsc4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
arp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC8C9.12cmitochondrial iron ion transporter (predicted) Positive GeneticPMID:22681890
zip2vacuolar membrane zinc transporter (predicted) Positive GeneticPMID:22681890
vps1dynamin family protein Vps1 Positive GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
SPAP27G11.02TPR repeat protein, involved in mitochondrial protein turnover (predicted) Positive GeneticPMID:22681890
vps3CORVET complex subunit, GTPase regulator Vps3 (predicted) Positive GeneticPMID:22681890
cay1cactin, spliceosome complex subunit (predicted) Negative GeneticPMID:18818364
hrp1ATP-dependent DNA helicase Hrp1 Phenotypic EnhancementPMID:23032292
Phenotypic EnhancementPMID:23103765
Synthetic Lethality
Synthetic LethalityPMID:15908586
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
swi6HP1 family chromodomain protein Swi6 Affinity Capture-WesternPMID:22990236
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
Contact Curators
External References
Database Identifier Description
NBRP SPAC3G6.01 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3G6.01 Retrieval of eukaryotic orthologs
BioGrid SPAC3G6.01 BioGRID Interaction Datasets
Bähler Lab SPAC3G6.01 Cell Cycle Expression Profile
Bähler Lab SPAC3G6.01 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC3G6.01 Pheromone response/mating expression profiles
Bähler Lab SPAC3G6.01 Environmental stress expression profiles
Bähler Lab SPAC3G6.01 Bähler Lab Transcriptome Viewer
Cyclebase SPAC3G6.01 Cell Cycle Data
PInt SPAC3G6.01 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC3G6.01 Entrez Gene
EntrezGene2543064ATP-dependent DNA helicase Hrp3
Uniprot_genenameHRP3
WikiGene2543064ATP-dependent DNA helicase Hrp3
SPD / RIKEN30/30G04Orfeome Localization Data
UniProtKB/SwissProtO14139Chromodomain helicase hrp3
ModBaseO14139Database of comparative protein structure models
Pfam Protein DomainsO14139Pfam Domain Arrangement
RefSeq PeptideNP_594967ATP-dependent DNA helicase Hrp3
RefSeq mRNANM_001020398972h- ATP-dependent DNA helicase Hrp3 (hrp3), mRNA
European Nucleotide ArchiveCAB16277ENA Protein Mapping
UniParcUPI000012CBCCUniProt Archive

Literature for hrp3
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013