erv1 (SPAC3G6.08)


Gene Standard Nameerv1 Characterisation Statusbiological_role_inferred
Systematic IDSPAC3G6.08 Feature Typeprotein coding
Synonyms Name Description
Productmitochondrial sulfhydryl oxidase (predicted) Product Size182aa, 20.77 kDa
Genomic Location Chromosome I, 5393499-5394534 (1036nt); CDS:5393688-5394236 (549nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003756protein disulfide isomerase activityISOSGD:S000003261GO_REF:000002412
GO:0016972thiol oxidase activityISOSGD:S000003261GO_REF:00000243
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006879cellular iron ion homeostasisISOSGD:S000003261GO_REF:000002424
GO:0007005mitochondrion organizationISOSGD:S000003261GO_REF:0000024282
GO:0006457protein foldingISOSGD:S000003261GO_REF:0000024111
GO:0045041protein import into mitochondrial intermembrane spaceISOSGD:S000003261GO_REF:00000246
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005758mitochondrial intermembrane spaceISOSGD:S000003261GO_REF:000002429
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyerv1ΔNullPECO:0000005, PECO:0000137PMID:236978061315
Microscopyerv1ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002111inviable bottle-shaped vegetative cell134
penetrance FYPO_EXT:0000001Microscopyerv1ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
153934995394534

UTRs

Region Coordinates Reference
five_prime_UTR5393499..5393687PMID:21511999
three_prime_UTR5394237..5394534PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04777 Pfam IPR017905 ERV/ALR sulfhydryl oxidase domain 84 171 2
PS51324 Prosite Profiles IPR017905 ERV/ALR sulfhydryl oxidase domain 75 177 2
PTHR12645:SF0 HMMPANTHER 6 176 1
PTHR12645 HMMPANTHER 6 176 2
1.20.120.310 Gene3D IPR017905 ERV/ALR sulfhydryl oxidase domain 77 177 2
SSF69000 SuperFamily IPR017905 ERV/ALR sulfhydryl oxidase domain 77 175 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.12 Da
Charge 1.00
Isoelectric point 7.15
Molecular weight 20.77 kDa
Number of residues 182
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
1876.58during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.44during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
2.3during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC3G6.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3G6.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC3G6.08 BioGRID Interaction Datasets
Expression Viewer SPAC3G6.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC3G6.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC3G6.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC3G6.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC3G6.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC3G6.08 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC3G6.08 Cell Cycle Data
GEO SPAC3G6.08 GEO profiles
PInt SPAC3G6.08 Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene2543175sulfhydryl oxidase (predicted)
WikiGene2543175sulfhydryl oxidase (predicted)
SPD / RIKEN05/05F04Orfeome Localization Data
UniProtKB/SwissProtO14144Mitochondrial FAD-linked sulfhydryl oxidase erv1
ModBaseO14144Database of comparative protein structure models
STRINGO14144Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594974sulfhydryl oxidase (predicted)
RefSeq mRNANM_001020405972h- sulfhydryl oxidase (predicted) (erv1), mRNA
European Nucleotide ArchiveCAB16284ENA Protein Mapping
European Nucleotide ArchiveCAB16284.1ENA Protein Mapping
UniParcUPI000006B711UniProt Archive

Literature for erv1

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014