erv1 (SPAC3G6.08)


Gene Standard Nameerv1 Characterisation Statusbiological_role_inferred
Systematic IDSPAC3G6.08 Feature Typeprotein coding
Synonyms Name Description
Productmitochondrial sulfhydryl oxidase (predicted) Product Size182aa, 20.77 kDa
Genomic Location Chromosome I, 5393499-5394534 (1036nt); CDS:5393688-5394236 (549nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein disulfide isomerase activity10
Annotation ExtensionEvidenceWith/FromReference
thiol oxidase activity3
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cellular iron ion homeostasis22
Annotation ExtensionEvidenceWith/FromReference
mitochondrion organization294
Annotation ExtensionEvidenceWith/FromReference
protein folding106
Annotation ExtensionEvidenceWith/FromReference
protein import into mitochondrial intermembrane space6
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
mitochondrial intermembrane space26
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyerv1ΔNullPECO:0000005, PECO:0000137PMID:236978061338
Microscopyerv1ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002111inviable tapered vegetative cell134
penetrance FYPO_EXT:0000001Microscopyerv1ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
153934995394534

UTRs

Region Coordinates Reference
five_prime_UTR5393499..5393687PMID:21511999
three_prime_UTR5394237..5394534PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04777 Pfam IPR017905 ERV/ALR sulfhydryl oxidase domain 84 171 2
PS51324 Prosite Profiles IPR017905 ERV/ALR sulfhydryl oxidase domain 75 177 2
PTHR12645 HMMPANTHER 6 175 2
PTHR12645:SF0 HMMPANTHER 6 175 2
1.20.120.310 Gene3D IPR017905 ERV/ALR sulfhydryl oxidase domain 77 177 2
SSF69000 SuperFamily IPR017905 ERV/ALR sulfhydryl oxidase domain 77 175 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.12 Da
Charge 1.00
Isoelectric point 7.15
Molecular weight 20.77 kDa
Number of residues 182
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1876.58during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.3during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.44during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC3G6.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3G6.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC3G6.08 BioGRID Interaction Datasets
Expression Viewer SPAC3G6.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC3G6.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC3G6.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC3G6.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC3G6.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC3G6.08 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC3G6.08 Cell Cycle Data
GEO SPAC3G6.08 GEO profiles
PInt SPAC3G6.08 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC3G6.08 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC3G6.08 Fission yeast phenotypic data & analysis
SPD / RIKEN05/05F04Orfeome Localization Data
UniProtKB/SwissProtO14144Mitochondrial FAD-linked sulfhydryl oxidase erv1
ModBaseO14144Database of comparative protein structure models
STRINGO14144Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594974mitochondrial sulfhydryl oxidase (predicted)
RefSeq mRNANM_001020405972h- mitochondrial sulfhydryl oxidase (predicted) (erv1), mRNA
European Nucleotide ArchiveCAB16284.1ENA Protein Mapping
UniParcUPI000006B711UniProt Archive

Literature for erv1

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014