erv1 (SPAC3G6.08)

Gene Standard Nameerv1 Characterisation Statusbiological_role_inferred
Systematic IDSPAC3G6.08 Feature Typeprotein coding
Synonyms Name Description
Productmitochondrial sulfhydryl oxidase (predicted) Product Size182aa, 20.77 kDa
Genomic Location Chromosome I, 5393499-5394534 (1036nt); CDS:5393688-5394236 (549nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003756protein disulfide isomerase activityISOSGD:S000003261GO_REF:000002410
GO:0016972thiol oxidase activityISOSGD:S000003261GO_REF:00000243
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006879cellular iron ion homeostasisISOSGD:S000003261GO_REF:000002422
GO:0007005mitochondrion organizationISOSGD:S000003261GO_REF:0000024294
GO:0006457protein foldingISOSGD:S000003261GO_REF:0000024106
GO:0045041protein import into mitochondrial intermembrane spaceISOSGD:S000003261GO_REF:00000246
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005758mitochondrial intermembrane spaceISOSGD:S000003261GO_REF:000002426
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyerv1ΔNullPECO:0000005, PECO:0000137PMID:236978061338

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002111inviable tapered vegetative cell134
penetrance FYPO_EXT:0000001Microscopyerv1ΔNullPECO:0000005, PECO:0000137PMID:23697806
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04777 Pfam IPR017905 ERV/ALR sulfhydryl oxidase domain 84 171 2
PS51324 Prosite Profiles IPR017905 ERV/ALR sulfhydryl oxidase domain 75 177 2
PTHR12645 HMMPANTHER 6 175 2
PTHR12645:SF0 HMMPANTHER 6 175 2 Gene3D IPR017905 ERV/ALR sulfhydryl oxidase domain 77 177 2
SSF69000 SuperFamily IPR017905 ERV/ALR sulfhydryl oxidase domain 77 175 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.12 Da
Charge 1.00
Isoelectric point 7.15
Molecular weight 20.77 kDa
Number of residues 182
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1876.58during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.3during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.44during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPAC3G6.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3G6.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC3G6.08 BioGRID Interaction Datasets
Expression Viewer SPAC3G6.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC3G6.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC3G6.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC3G6.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC3G6.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC3G6.08 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC3G6.08 Cell Cycle Data
GEO SPAC3G6.08 GEO profiles
PInt SPAC3G6.08 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC3G6.08 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC3G6.08 Fission yeast phenotypic data & analysis
SPD / RIKEN05/05F04Orfeome Localization Data
UniProtKB/SwissProtO14144Mitochondrial FAD-linked sulfhydryl oxidase erv1
ModBaseO14144Database of comparative protein structure models
STRINGO14144Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594974mitochondrial sulfhydryl oxidase (predicted)
RefSeq mRNANM_001020405972h- mitochondrial sulfhydryl oxidase (predicted) (erv1), mRNA
European Nucleotide ArchiveCAB16284.1ENA Protein Mapping
UniParcUPI000006B711UniProt Archive

Literature for erv1

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014