SPAC3H5.09c


Gene Standard NameUnassigned Characterisation Statusconserved_unknown
Systematic IDSPAC3H5.09c Feature Typeprotein coding
Synonyms Name Description
Productconserved eukaryotic mitochondrial protein (predicted) Product Size2699aa, 311.84 kDa
Genomic Location Chromosome I, 3416544-3425062 (8519nt); CDS:3416722-3424821 (8100nt)

Ensembl Gene Location
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371017
GO:0005739mitochondrionISOSGD:S000004446GO_REF:0000024758
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPAC3H5.09cΔNullPMID:204732893730
MicroscopySPAC3H5.09cΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001510viable vegetative cell, abnormal cell shape, normal cell size215
expressivity FYPO_EXT:0000003
penetrance FYPO_EXT:0000001
MicroscopySPAC3H5.09cΔNullPECO:0000137, PECO:0000005PMID:23697806
expressivity FYPO_EXT:0000003
penetrance FYPO_EXT:0000001
MicroscopySPAC3H5.09cΔNullPECO:0000137, PECO:0000004PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
134165443425062

UTRs

Region Coordinates Reference
five_prime_UTR3416544..3416721PMID:21511999
three_prime_UTR3424822..3425062PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF10359 Pfam IPR019449 FMP27, WPPW domain 1588 2073 1
PF10344 Pfam IPR019439 FMP27, N-terminal 34 808 1
PF10351 Pfam IPR019443 FMP27, C-terminal 2088 2548 1
PF10305 Pfam IPR019415 FMP27, SW domain 1054 1156 1
PF10293 Pfam IPR019409 FMP27, domain of unknown function DUF2405 824 979 1
PF10347 Pfam IPR019441 FMP27, GFWDK domain 1174 1330 1
TMhelix TMHMM 24 46 959
PTHR15678:SF6 HMMPANTHER 6 2699 1
PTHR15678 HMMPANTHER 6 2699 1
Coil ncoils Rabaptin coiled-coil domain 304 325 968
Coil ncoils Rabaptin coiled-coil domain 1759 1780 968
Coil ncoils Rabaptin coiled-coil domain 1786 1814 968
Coil ncoils Rabaptin coiled-coil domain 2561 2582 968

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.54 Da
Charge 41.50
Isoelectric point 7.61
Molecular weight 311.84 kDa
Number of residues 2699
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS1041PMID:217125471669
present during mitotic M phase
present during mitotic M phaseS1028PMID:21712547
S2451PMID:24763107
S1028PMID:24763107
present during mitotic M phaseS2451PMID:21712547
MOD:00047O-phospho-L-threonineT2456PMID:21712547689
present during mitotic M phase
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
289during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
246during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
357during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
273during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
287.61during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
314during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.9during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.88during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999433
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPAC3H5.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3H5.09c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC3H5.09c BioGRID Interaction Datasets
Expression Viewer SPAC3H5.09c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC3H5.09c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC3H5.09c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC3H5.09c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC3H5.09c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC3H5.09c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC3H5.09c Cell Cycle Data
GEO SPAC3H5.09c GEO profiles
PInt SPAC3H5.09c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC3H5.09c Peptides identified in tandem mass spectrometry proteomics experiments
WikiGene2543405conserved eukaryotic mitochondrial protein (predicted)
EntrezGene2543405conserved eukaryotic mitochondrial protein (predicted)
SPD / RIKEN51/51F02Orfeome Localization Data
UniProtKB/SwissProtQ6LA55UPF0648 protein C3H5.09c
ModBaseQ6LA55Database of comparative protein structure models
STRINGQ6LA55Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594183conserved eukaryotic mitochondrial protein (predicted)
RefSeq mRNANM_001019607972h- conserved eukaryotic mitochondrial protein (predicted) (SPAC3H5.09c), mRNA
European Nucleotide ArchiveCAB16593ENA Protein Mapping
European Nucleotide ArchiveCAB16593.2ENA Protein Mapping
UniParcUPI000228F36CUniProt Archive

Literature for SPAC3H5.09c

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014