rpl501 (SPAC3H5.12c)


Gene Standard Namerpl501 Characterisation Statusbiological_role_inferred
Systematic IDSPAC3H5.12c Feature Typeprotein coding
Synonymsrpl5, rpl5-1 Name Description
Product60S ribosomal protein L5 (predicted) Product Size294aa, 33.46 kDa
Genomic Location Chromosome I, 3410909-3411881 (973nt); CDS:3410951-3411835 (885nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
5S rRNA binding2
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation465
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis338
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to bortezomibrpl501ΔNull256
viable vegetative cell populationrpl501ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyrpl501ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3410909..3411881
mRNA3410909..3411881
5' UTR3410909..3410950PMID:21511999
CDS3410951..3411835
3' UTR3411836..3411881PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00861 Pfam IPR005484 Ribosomal protein L18/L5 26 173 2
PF14204 Pfam IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal 193 287 2
PTHR23410 HMMPANTHER IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 2 294 2
3.30.420.100 Gene3D 12 252 2
SSF53137 SuperFamily 140 253 7
SSF53137 SuperFamily 12 112 7
MF_01337_A hamap IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 14 247 2
PR00058 PRINTS IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 84 104 2
PR00058 PRINTS IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 207 227 2
PR00058 PRINTS IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 145 164 2
PR00058 PRINTS IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 165 184 2
PR00058 PRINTS IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 20 39 2
PR00058 PRINTS IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal 43 62 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 113.81 Da
Charge 8.50
Isoelectric point 9.46
Molecular weight 33.46 kDa
Number of residues 294
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS9
present during cellular response to thiabendazoleS10
present during mitotic M phase, cellular response to thiabendazoleS176
present during mitotic M phase, cellular response to thiabendazoleS167
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S9 PMID:21712547
present during cellular response to thiabendazole IDA S10 PMID:18257517
present during cellular response to thiabendazole IDA S167 PMID:18257517
present during mitotic M phase experimental evidence S167 PMID:21712547
present during mitotic M phase experimental evidence S176 PMID:21712547
present during cellular response to thiabendazole IDA S176 PMID:18257517
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
330819.6during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
56167.62during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
72during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
8.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in bacteria1001
conserved in metazoa3424
conserved in vertebrates3399
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bynak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
affinity captured bysog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
binds DNA-binding domain construct withzfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Two-hybridPMID:19682301
External References
Database Identifier Description
NBRP SPAC3H5.12c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC3H5.12c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC3H5.12c BioGRID Interaction Datasets
Expression Viewer SPAC3H5.12c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC3H5.12c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC3H5.12c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC3H5.12c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC3H5.12c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC3H5.12c Transcriptome Viewer (Bähler Lab)
GEO SPAC3H5.12c GEO profiles
PInt SPAC3H5.12c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC3H5.12c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC3H5.12c Fission yeast phenotypic data & analysis
Cyclebase SPAC3H5.12c.1 Cell Cycle Data
UniProtKB/SwissProtP5282260S ribosomal protein L5-A
ModBaseP52822Database of comparative protein structure models
STRINGP52822Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59418060S ribosomal protein L5
RefSeq mRNANM_001019604972h- 60S ribosomal protein L5 (rpl501), mRNA
European Nucleotide ArchiveAAB05674.1ENA Protein Mapping
European Nucleotide ArchiveCAB16596.1ENA Protein Mapping
UniParcUPI000013410DUniProt Archive

Literature for rpl501

Search: Europe PMC or PubMed

Release Version: PomBase:26_52 - 11 May 2015