esc1 (SPAC56F8.16)

Gene Standard Nameesc1 ChromosomeI
Systematic IDSPAC56F8.16 Gene Start1153572
Synonyms Gene End1156804
Producttranscription factor Esc1 (predicted) Gene Length3233
Feature Typeprotein coding CDS Start1154733
Name Description CDS End1155974
Characterisation Statuspublished CDS Length1242

Ensembl Gene Location
  1. SPNCRNA.716
  2. SPAC56F8.12
  3. mug115
  4. SPAC56F8.13
  5. SPAC56F8.15
  6. esc1
  7. pso2
  8. mug103
  9. csn4
  10. rps2201
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyesc1delta (deletion)deletionPMID:20473289
GO Molecular Function

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingNASGO_REF:0000051
GO:0003677DNA bindingISMPFAM:PF00010GO_REF:0000001
GO:0046983protein dimerization activityIEAIPR011598GO_REF:0000002
GO Biological Process

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0006357regulation of transcription from RNA polymerase II promoterNASGO_REF:0000051
GO:0030154cell differentiationIEAUniProtKB:KW-0221GO_REF:0000037
GO:0031142induction of conjugation upon nitrogen starvationIMPPMID:8381348
GO:0045893positive regulation of transcription, DNA-dependentIMPPMID:8381348
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
111535721156804

References

Region Start End Reference
five_prime_UTR11535721154732PMID:21511999
three_prime_UTR11559751156804PMID:21511999
three_prime_UTR11559751156804PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00010 IPR011598 Pfam Myc-type, basic helix-loop-helix (bHLH) domain 336 385 4
SM00353 IPR011598 SMART Myc-type, basic helix-loop-helix (bHLH) domain 340 391 4
PS50888 IPR011598 Prosite Profiles Myc-type, basic helix-loop-helix (bHLH) domain 334 385 4
G3DSA:4.10.280.10 IPR011598 Gene3D 336 405 4
SSF47459 IPR011598 SuperFamily 333 404 4
Coil ncoils Rabaptin coiled-coil domain 382 403 974
PTHR22934:SF16 hmmpanther 1 412 1
PTHR22934 hmmpanther 1 412 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 108.47 Da
Charge 11.00
Isoelectric point 9.36
Molecular weight 44.80 kDa
Number of residues 413
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2835.02PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide4.4PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide9.6PMID:23101633
Species Distribution
DescriptionQualifierReference
orthologs cannot be distinguished
conserved in fungi
conserved in eukaryotes
conserved in eukaryotes only
Contact Curators
Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
cyr1adenylate cyclase Dosage RescuePMID:16143612
pka1cAMP-dependent protein kinase catalytic subunit Pka1 Dosage RescuePMID:16143612
Contact Curators
External References
Database Identifier Description
NBRP SPAC56F8.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC56F8.16 Retrieval of eukaryotic orthologs
BioGrid SPAC56F8.16 BioGRID Interaction Datasets
Bähler Lab SPAC56F8.16 Cell Cycle Expression Profile
Bähler Lab SPAC56F8.16 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC56F8.16 Pheromone response/mating expression profiles
Bähler Lab SPAC56F8.16 Environmental stress expression profiles
Bähler Lab SPAC56F8.16 Bähler Lab Transcriptome Viewer
Cyclebase SPAC56F8.16 Cell Cycle Data
PInt SPAC56F8.16 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC56F8.16 Entrez Gene
SPD / RIKEN19/19H01Orfeome Localization Data
WikiGene2543286transcription factor Esc1 (predicted)
Uniprot_genenameESC1
EntrezGene2543286transcription factor Esc1 (predicted)
UniProtKB/SwissProtQ04635Protein esc1
ModBaseQ04635Database of comparative protein structure models
Pfam Protein DomainsQ04635Pfam Domain Arrangement
RefSeq PeptideNP_593230transcription factor Esc1 (predicted)
RefSeq mRNANM_001018627972h- transcription factor Esc1 (predicted) (esc1), mRNA
European Nucleotide ArchiveCAA49186ENA Protein Mapping
European Nucleotide ArchiveCAA93587ENA Protein Mapping
UniParcUPI000012A1A6UniProt Archive

Literature for esc1
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013