dam1 (SPAC589.08c)


Gene Standard Namedam1 Characterisation Statuspublished
Systematic IDSPAC589.08c Feature Typeprotein coding
Synonyms Name Description
ProductDASH complex subunit Dam1 Product Size155aa, 17.44 kDa
Genomic Location Chromosome I, 3106934-3106191 (744nt); CDS:3106841-3106374 (468nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
attachment of mitotic spindle microtubules to kinetochore41
Annotation ExtensionEvidenceWith/FromReference
microtubule sliding4
Annotation ExtensionEvidenceWith/FromReference
mitotic metaphase chromosome recapture2
Annotation ExtensionEvidenceWith/FromReference
mitotic sister chromatid biorientation16
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
condensed nuclear chromosome kinetochore61
cytosol2302
Annotation ExtensionEvidenceWith/FromReference
DASH complex10
Annotation ExtensionEvidenceWith/FromReference
mitotic spindle271
Annotation ExtensionEvidenceWith/FromReference
mitotic spindle polar microtubule2
Annotation ExtensionEvidenceWith/FromReference
mitotic spindle pole body220
Annotation ExtensionEvidenceWith/FromReference
nucleus2691
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
decreased cell population growth on glucose carbon sourcedam1Δ320
loss of viability at high temperaturedam1Δ56
normal growth on glucose carbon sourceT136A (T136A)287
S143D (S143D)
S143A (S143A)
dam1(1-127) (128-155)
T139A (T139A)
resistance to thiabendazoledam1-A8-ts (H126R, E149G)17
S143A (S143A)
S143D (S143D)
dam1(1-127) (128-155)
sensitive to cadmiumdam1Δ249
sensitive to hydroxyureadam1Δ580
sensitive to osmotic stressdam1Δ110
sensitive to potassium chloridedam1Δ19
sensitive to thiabendazoledam1Δ327
viable vegetative cell populationdam1Δ3844

Cell Phenotype

Term NameGenotypesCount
abnormal cell cycle arrest in mitotic metaphase with long polar microtubulesdam1+1
abnormal centromere clustering at nuclear peripherydam1Δ8
abnormal mitotic chromosome congressiondam1-A8-ts (H126R, E149G)6
abolished kinetochore sliding during chromosome recapturedam1Δ1
abolished protein phosphorylation during mitotic M phase4
affecting dam1S143A (S143A)
cutdam1Δ128
increased activation of mitotic cell cycle spindle assembly checkpointdam1Δ16
increased duration of protein localization to mitotic spindle10
affects localization of cdc13dam1Δ
increased protein localization to kinetochore during vegetative growth4
affects localization of mad2dam1Δ
affects localization of bub1dam1Δ
lagging mitotic chromosomesdam1Δ40
long mitotic spindledam1Δ24
mitotic chromosome fragmentation upon segregationdam1Δ5
mitotic metaphase/anaphase transition delaydam1Δ19
mitotic spindle collapsedam1Δ9
normal centromere clustering at nuclear peripheryS143A (S143A)7
S143D (S143D)
normal protein binding77
affecting dam1 and ask1S143A (S143A)
normal protein localization272
affecting ask1S143A (S143A)
normal protein localization to kinetochore during vegetative growth29
affecting dis1dam1Δ
normal protein phosphorylation during mitosis3
affecting dam1T139A (T139A)
affecting dam1T136A (T136A)
separate mitotic half spindles presentdam1Δ5
unequal mitotic sister chromatid segregationdam1Δ63
viable vegetative celldam1Δ3652
viable vegetative cell with normal cell morphologydam1Δ3100

FYPO Multi-allele Phenotypes

Population Phenotype

Term NameGenotypes
decreased cell population growth on glucose carbon sourceT136A (T136A), dis2Δ
klp5Δ, dam1(1-127) (128-155)
dis2Δ, T139A (T139A)
S143D (S143D), dis2Δ
S143A (S143A), klp5Δ
klp5Δ, S143D (S143D)
dam1Δ, mad3Δ
inviable vegetative cell populationS143A (S143A), dis2Δ, mad3Δ
klp5Δ, dam1-A8-ts (H126R, E149G)
dam1-A8-ts (H126R, E149G), klp6Δ
dam1Δ, dis2Δ
dam1(1-127) (128-155), dis2Δ
dam1(1-127) (128-155), dis2Δ, mad3Δ
dam1Δ, dis2Δ, mad3Δ
klp5Δ, dam1Δ
S143A (S143A), dis2Δ
normal growth on glucose carbon sourceS143A (S143A), mad3Δ
dam1(1-127) (128-155), mad3Δ
normal growth on thiabendazoleklp5Δ, dam1-A8-ts (H126R, E149G)
resistance to thiabendazoleklp5Δ, dam1-A8-ts (H126R, E149G)
viable vegetative cell populationklp5Δ, dam1-A8-ts (H126R, E149G)

Cell Phenotype

Term NameGenotypes
abnormal mitotic chromosome congressiondam1-A8-ts (H126R, E149G), klp6Δ
abnormal mitotic sister chromatid biorientationdam1-A8-ts (H126R, E149G), klp6Δ
abnormal mitotic sister chromatid segregationklp5Δ, dam1-A8-ts (H126R, E149G)
fragmented DNA during vegetative growthklp5Δ, dam1-A8-ts (H126R, E149G)
lagging mitotic chromosomesklp5Δ, dam1-A8-ts (H126R, E149G)
large and small daughter nucleiklp5Δ, dam1-A8-ts (H126R, E149G)
unequal mitotic sister chromatid segregationklp5Δ, dam1-A8-ts (H126R, E149G)
dam1-A8-ts (H126R, E149G), klp6Δ
S143A (S143A), klp5Δ
nda3-KM311, S143A (S143A)
Target Of
OntologyRelationshipGeneProduct
FYPO affected by mutation in ask1 DASH complex subunit Ask1
FYPO affected by mutation in dam1 DASH complex subunit Dam1
FYPO affected by mutation in duo1 DASH complex subunit Duo1
FYPO affected by mutation in plo1 Polo kinase Plo1
FYPO localization affected by mutation in ask1 DASH complex subunit Ask1
FYPO localization affected by mutation in dad1 DASH complex subunit Dad1
FYPO localization affected by mutation in dad2 DASH complex subunit Dad2
FYPO localization affected by mutation in duo1 DASH complex subunit Duo1
FYPO localization affected by mutation in mal2 kinetochore protein, CENP-O ortholog Mal2
FYPO localization affected by mutation in mis6 kinetochore protein, CENP-I ortholog Mis6
FYPO localization affected by mutation in spc34 DASH complex subunit Spc34
GO substrate of plo1 Polo kinase Plo1
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3106934..3106191
mRNA3106934..3106191
5' UTR3106934..3106842PMID:21511999
CDS3106841..3106374
3' UTR3106373..3106191PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF08653 Pfam IPR013962 DASH complex subunit Dam1 34 88 1
PTHR28113 HMMPANTHER 1 155 1
PD398536 blastprodom IPR013962 DASH complex subunit Dam1 27 84 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.54 Da
Charge -6.50
Codon Adaptation Index 0.43
Isoelectric point 4.55
Molecular weight 17.44 kDa
Number of residues 155
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1677
added by plo1S143
Annotation ExtensionEvidenceResidueReference
added by plo1 IDA S143 PMID:22375062
phosphorylated residue 1932
added during mitotic M phase
removed during mitotic anaphase
absent during mitotic G2 phase
Annotation ExtensionEvidenceResidueReference
added during mitotic M phase IDA PMID:22375062
removed during mitotic anaphase IDA PMID:22375062
absent during mitotic G2 phase IDA PMID:22375062
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreased during GO:0071456expression microarray evidencePMID:22235339

Quantitative Gene Expression

View graphical display of gene expression data for dam1 (SPAC589.08c)

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.63during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.18during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi only618
conserved in fungi4606
conserved in eukaryotes4516
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC589.08c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturesduo1DASH complex subunit Duo1 Affinity Capture-MSPMID:16079914
affinity capturesspc34DASH complex subunit Spc34 Affinity Capture-MSPMID:16079914
affinity capturesdad2DASH complex subunit Dad2 Affinity Capture-MSPMID:16079914
affinity capturesdad1DASH complex subunit Dad1 Affinity Capture-MSPMID:16079914
affinity capturesdad3DASH complex subunit Dad3 Affinity Capture-MSPMID:16079914
affinity capturesask1DASH complex subunit Ask1 Affinity Capture-MSPMID:16079914
affinity captured bydad1DASH complex subunit Dad1 Affinity Capture-MSPMID:16079914
affinity captured byask1DASH complex subunit Ask1 Affinity Capture-WesternPMID:22375062
binds activation domain construct withnde1mitochondrial NADH dehydrogenase (ubiquinone) Nde1 (predicted) Two-hybridPMID:26771498
binds activation domain construct withspc34DASH complex subunit Spc34 Two-hybridPMID:26771498
binds activation domain construct withduo1DASH complex subunit Duo1 Two-hybridPMID:26771498
binds DNA-binding domain construct withdad1DASH complex subunit Dad1 Two-hybridPMID:26771498
modified byplo1Polo kinase Plo1 Biochemical ActivityPMID:22375062
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPAC589.08c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
synthetic lethal withklp6kinesin-like protein Klp6 Synthetic LethalityPMID:16079915
synthetic lethal withmis6kinetochore protein, CENP-I ortholog Mis6 Synthetic LethalityPMID:16079915
synthetic lethal withmal2kinetochore protein, CENP-O ortholog Mal2 Synthetic LethalityPMID:16079915
synthetic lethal withklp5kinesin-like protein Klp5 Synthetic LethalityPMID:16079915
synthetic lethal withspc7NMS complex subunit, Spc105/KNL-1 family member, blinkin, Spc7 Synthetic LethalityPMID:22521786
synthetic lethal withcsi1mitotic chromosome segregation protein Csi1 Synthetic LethalityPMID:23166349
negative genetic interaction withSPAC1296.01cphosphoacetylglucosamine mutase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtma20RNA-binding protein Tma20 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC18.17cproteasome assembly chaperone (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhrq1RecQ type DNA helicase Hrq1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmrpl1mitochondrial ribosomal protein subunit L1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspo20sec14 cytosolic factor family, glycerophospholipid-transfer protein Spo20/Sec14 Negative GeneticPMID:22681890
negative genetic interaction withhhf2histone H4 h4.2 Negative GeneticPMID:22681890
negative genetic interaction withpsl1cyclin pho85 family Psl1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpuf2pumilio family RNA-binding protein Puf2 Negative GeneticPMID:22681890
negative genetic interaction withbdf2BET family double bromodomain protein Bdf2 Negative GeneticPMID:22681890
negative genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmet10sulfite reductase NADPH flavoprotein subunit (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtos4FHA domain protein Tos4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withulp2SUMO deconjugating cysteine peptidase Ulp2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhat1histone acetyltransferase Hat1 Negative GeneticPMID:22681890
negative genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
negative genetic interaction withpam17TIM23 translocase complex-associated motor subunit Pam17 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withswc2Swr1 complex complex subunit Swc2 Negative GeneticPMID:22681890
negative genetic interaction withrhp18Rad18 homolog ubiquitin protein ligase E3, Rhp18 Negative GeneticPMID:22681890
negative genetic interaction withlub1WD repeat protein Lub1 Negative GeneticPMID:22681890
negative genetic interaction withrtt109RTT109 family histone lysine acetyltransferase Negative GeneticPMID:22681890
negative genetic interaction withclp1Cdc14-related protein phosphatase Clp1/Flp1 Negative GeneticPMID:22681890
negative genetic interaction withmgr2TIM23 translocase complex subunit Mgr2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpmt3SUMO Negative GeneticPMID:22681890
negative genetic interaction withuri1unconventional prefoldin chaperone involved protein complex assembly Uri1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC13E7.03cRNA hairpin binding protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC17H9.08mitochondrial coenzyme A transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC70.03cproline dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvps3CORVET complex subunit, GTPase regulator Vps3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withmms1E3 ubiquitin ligase complex subunit Mms1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witherg28Erg28 protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withctp1CtIP-related endonuclease Negative GeneticPMID:22681890
negative genetic interaction withash2Ash2-trithorax family protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC70.08cmethyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withalp16gamma tubulin complex subunit Alp16 Negative GeneticPMID:22681890
negative genetic interaction withSPBC32H8.01cconserved fungal protein, involved in endocytic trafficking (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdsk1SR protein-specific kinase Dsk1 Negative GeneticPMID:22681890
negative genetic interaction withhcr1translation initiation factor eIF3j (p35) Negative GeneticPMID:22681890
negative genetic interaction withpmc2mediator complex subunit Med1 Negative GeneticPMID:22681890
negative genetic interaction withmsd1microtubule-anchoring factor Msd1 Negative GeneticPMID:22681890
negative genetic interaction withleo1RNA polymerase II associated Paf1 complex (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnaa38NatC N-acetyltransferase non-catalytic Sm-like domain subunit Naa38 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsck2serine/threonine protein kinase Sck2 Negative GeneticPMID:24463365
negative genetic interaction withSPCC1840.05cphosphoglucomutase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcsi2mitotic chromosome segregation protein Csi2 Negative GeneticPMID:22681890
negative genetic interaction withrtf2replication termination factor Rtf2 Negative GeneticPMID:22681890
negative genetic interaction withrga8Rho-type GTPase activating protein Rga8 Negative GeneticPMID:22681890
negative genetic interaction withbob1prefoldin subunit 5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withbqt4bouquet formation protein Bqt4 Negative GeneticPMID:22681890
negative genetic interaction withubx2UBX domain protein Ubx2 Negative GeneticPMID:22681890
negative genetic interaction withmrf1mitochondrial peptide chain release factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsnt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
negative genetic interaction withSPAC1F5.03cFAD-dependent oxidoreductase involved in late endosome to Golgi transport (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpt419S proteasome regulatory subunit Rpt4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withapq12nuclear membrane organization protein Apq12 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmph1dual specificity protein kinase Mph1 Negative GeneticPMID:22681890
negative genetic interaction withset1histone lysine methyltransferase Set1 Negative GeneticPMID:22681890
negative genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppk26protein kinase like PAN complex subunit Ppk26 Negative GeneticPMID:22681890
negative genetic interaction withdcd1deoxycytidylate deaminase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsrb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Negative GeneticPMID:22681890
negative genetic interaction withvps1301chorein homolog Vps13a (predicted) Negative GeneticPMID:22681890
negative genetic interaction withatd1aldehyde dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpan52-dehydropantoate 2-reductase Pan5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvht1vitamin H transmembrane transporter Vht1 Negative GeneticPMID:22681890
negative genetic interaction withnem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
negative genetic interaction withmsc1Swr1 complex subunit Chk1 Negative GeneticPMID:22681890
negative genetic interaction witherd1Erd1 homolog (predicted) Negative GeneticPMID:22681890
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
negative genetic interaction withmpd2GYF domain protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC9G1.08cphospholipase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withire1serine/threonine protein kinase, sensor for unfolded proteins in the ER Ire1 Negative GeneticPMID:22681890
negative genetic interaction withgmh5alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC1921.04cdubious Negative GeneticPMID:22681890
negative genetic interaction withSPAC227.17cconserved eukaryotic protein, DUF3128, human c22orf39 ortholog Negative GeneticPMID:22681890
negative genetic interaction withsno1glutamine aminotransferase subunit Sno1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withies4Ino80 complex subunit Ies4 Negative GeneticPMID:22681890
negative genetic interaction withmad2mitotic spindle checkpoint protein Mad2 Negative GeneticPMID:22681890
negative genetic interaction withrps110240S ribosomal protein S11 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl300160S ribosomal protein L30 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmad3mitotic spindle checkpoint protein Mad3 Negative GeneticPMID:22681890
negative genetic interaction withSPAC13G6.09SSU-rRNA maturation protein Tsr4 homolog 2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withswr1SNF2 family ATP-dependent DNA helicase Swr1 Negative GeneticPMID:22681890
negative genetic interaction withasp1inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrps2340S ribosomal protein S23 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrps40140S ribosomal protein S4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Negative GeneticPMID:22681890
negative genetic interaction withadn2transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
negative genetic interaction withatp14F1-ATPase subunit H (predicted) Negative GeneticPMID:22681890
negative genetic interaction withegd2nascent polypeptide-associated complex alpha subunit Egd2 Negative GeneticPMID:22681890
negative genetic interaction witharb1argonaute inhibitor protein 1 Negative GeneticPMID:22681890
negative genetic interaction withnse6Smc5-6 complex non-SMC subunit Nse6 Negative GeneticPMID:22681890
negative genetic interaction withptp4phosphatidate cytidylyltransferase Ptp4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpli1SUMO E3 ligase Pli1 Negative GeneticPMID:22681890
negative genetic interaction withpof3F-box protein Pof3 Negative GeneticPMID:22681890
negative genetic interaction withatp10mitochondrial F1-F0 ATPase assembly protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
negative genetic interaction withnop52nucleolar protein Nop52 family Rrp1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvsl1vacuolar SNARE Vsl1/Vam7 Negative GeneticPMID:22681890
negative genetic interaction withgim3prefoldin subunit 4, Gim3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
negative genetic interaction withSPCC550.11karyopherin (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtls1splicing factor Tls1 Negative GeneticPMID:22681890
negative genetic interaction withmto1MT organizer Mto1 Negative GeneticPMID:22681890
negative genetic interaction withkap113karyopherin Kap113 Negative GeneticPMID:22681890
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
negative genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:22681890
negative genetic interaction withmhf2kinetochore protein, CENP-X ortholog, FANCM-MHF complex subunit Mhf2 Negative GeneticPMID:22681890
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:22681890
negative genetic interaction withset3histone lysine methyltransferase Set3 Negative GeneticPMID:22681890
negative genetic interaction withhap2HMG box protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withbut2But2 family protein But2 Negative GeneticPMID:22681890
negative genetic interaction withpop2F-box/WD repeat protein Pop2 Negative GeneticPMID:22681890
negative genetic interaction withrps250240S ribosomal protein S25 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC24B11.12cP-type ATPase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
positive genetic interaction withrpl200160S ribosomal protein L20a (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpex13peroxin 13 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsld3DNA replication pre-initiation complex subunit Sld3 Positive GeneticPMID:22681890
positive genetic interaction withgit5heterotrimeric G protein beta subunit Git5 Positive GeneticPMID:22681890
positive genetic interaction withask1DASH complex subunit Ask1 Positive GeneticPMID:22681890
positive genetic interaction withura1carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1 Positive GeneticPMID:22681890
positive genetic interaction withdeg1tRNA-pseudouridine synthase Deg1 (predicted) Positive GeneticPMID:22681890
synthetic growth defect withdis2serine/threonine protein phosphatase PP1, Dis2 Synthetic Growth DefectPMID:22375062
synthetic growth defect withklp5kinesin-like protein Klp5 Synthetic Growth DefectPMID:22375062
rescued bymad2mitotic spindle checkpoint protein Mad2 Phenotypic SuppressionPMID:24239120
overexpression rescuesmal3EB1 family Mal3 Dosage RescuePMID:16079915
overexpression rescuescdc13G2/M B-type cyclin Cdc13 Dosage RescuePMID:16079915
External References
Database Identifier Description
NBRP SPAC589.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC589.08c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC589.08c BioGRID Interaction Datasets
Expression Viewer SPAC589.08c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC589.08c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC589.08c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC589.08c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC589.08c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC589.08c Transcriptome Viewer (Bähler Lab)
GEO SPAC589.08c GEO profiles
PInt SPAC589.08c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC589.08c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC589.08c Fission yeast phenotypic data & analysis
Cyclebase SPAC589.08c.1 Cell Cycle Data
SPD / RIKEN41/41C05Orfeome Localization Data
UniProtKB/SwissProtQ9HDZ6DASH complex subunit dam1
ModBaseQ9HDZ6Database of comparative protein structure models
STRINGQ9HDZ6Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594056DASH complex subunit Dam1
RefSeq mRNANM_001019480972h- DASH complex subunit Dam1 (dam1), mRNA
European Nucleotide ArchiveCAC19765.1ENA Protein Mapping
UniParcUPI00000699F3UniProt Archive

Literature for dam1

Search: Europe PMC or PubMed

Release Version: PomBase:30_60 - 12 May 2016