alg14 (SPAC5D6.06c)


Gene Standard Namealg14 Characterisation Statusbiological_role_inferred
Systematic IDSPAC5D6.06c Feature Typeprotein coding
Synonyms Name Description
ProductUDP-GlcNAc transferase associated protein Alg14 (predicted) Product Size210aa, 23.21 kDa
Genomic Location Chromosome I, 1502635-1503758 (1124nt); CDS:1502909-1503587 (679nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
Term NameCount
dolichol-linked oligosaccharide biosynthetic process13
Annotation ExtensionEvidenceWith/FromReference
protein N-linked glycosylation32
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
endoplasmic reticulum596
Annotation ExtensionEvidenceWith/FromReference
integral component of endoplasmic reticulum membrane68
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationalg14ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyalg14ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1502635..1503373, 1503420..1503758
mRNA1502635..1503758
5' UTR1502635..1502908PMID:21511999
CDS1502909..1503373, 1503420..1503587
3' UTR1503588..1503758PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF08660 Pfam IPR013969 Oligosaccharide biosynthesis protein Alg14-like 37 209 1
TMhelix TMHMM 4 21 959
TMhelix TMHMM 106 128 959
TMhelix TMHMM 132 154 959
PTHR12154 HMMPANTHER IPR013969 Oligosaccharide biosynthesis protein Alg14-like 1 209 1
PTHR12154:SF2 HMMPANTHER 1 209 1
3.40.50.2000 Gene3D 41 207 15

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 110.52 Da
Charge 16.00
Isoelectric point 10.44
Molecular weight 23.21 kDa
Number of residues 210
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1817.46during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.56during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.47during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC5D6.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC5D6.06c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC5D6.06c BioGRID Interaction Datasets
Expression Viewer SPAC5D6.06c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC5D6.06c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC5D6.06c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC5D6.06c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC5D6.06c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC5D6.06c Transcriptome Viewer (Bähler Lab)
GEO SPAC5D6.06c GEO profiles
PInt SPAC5D6.06c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC5D6.06c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC5D6.06c Fission yeast phenotypic data & analysis
Cyclebase SPAC5D6.06c.1 Cell Cycle Data
SPD / RIKEN07/07H02Orfeome Localization Data
UniProtKB/SwissProtO14199UDP-N-acetylglucosamine transferase subunit alg14
ModBaseO14199Database of comparative protein structure models
STRINGO14199Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593363UDP-GlcNAc transferase associated protein Alg14 (predicted)
RefSeq mRNANM_001018795972h- UDP-GlcNAc transferase associated protein Alg14 (predicted) (alg14), mRNA
European Nucleotide ArchiveCAB10854.1ENA Protein Mapping
UniParcUPI000013AA18UniProt Archive

Literature for alg14

Search: Europe PMC or PubMed

Release Version: PomBase:26_52 - 11 May 2015