alg14 (SPAC5D6.06c)


Gene Standard Namealg14 Characterisation Statusbiological_role_inferred
Systematic IDSPAC5D6.06c Feature Typeprotein coding
Synonyms Name Description
ProductUDP-GlcNAc transferase associated protein Alg14 (predicted) Product Size210aa, 23.21 kDa
Genomic Location Chromosome I, 1502635-1503758 (1124nt); CDS:1502909-1503587 (679nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004577N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity2
contributes_toISOSGD:S000000274GO_REF:0000024
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006488dolichol-linked oligosaccharide biosynthetic processISSUniProtKB:P38242PMID:1561571813
GO:0006487protein N-linked glycosylationICGO:0006488GO_REF:000000132
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005783endoplasmic reticulumIDAPMID:16823372594
GO:0030176integral component of endoplasmic reticulum membraneISOSGD:S000000274GO_REF:000002467
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyalg14ΔNullPMID:204732893751
Microscopyalg14ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyalg14ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
115026351503373
215034201503758
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF08660 Pfam IPR013969 Oligosaccharide biosynthesis protein Alg14-like 37 209 1
TMhelix TMHMM 106 128 959
TMhelix TMHMM 4 21 959
TMhelix TMHMM 132 154 959
PTHR12154:SF0 HMMPANTHER 1 210 1
PTHR12154 HMMPANTHER IPR013969 Oligosaccharide biosynthesis protein Alg14-like 1 210 1
3.40.50.2000 Gene3D 41 207 15

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide278
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 110.52 Da
Charge 16.00
Isoelectric point 10.44
Molecular weight 23.21 kDa
Number of residues 210
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
1817.46during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.56during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.47during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4599
conserved in eukaryotes4514
conserved in metazoa3428
conserved in vertebrates3402
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC5D6.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC5D6.06c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC5D6.06c BioGRID Interaction Datasets
Expression Viewer SPAC5D6.06c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC5D6.06c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC5D6.06c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC5D6.06c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC5D6.06c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC5D6.06c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC5D6.06c Cell Cycle Data
GEO SPAC5D6.06c GEO profiles
PInt SPAC5D6.06c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC5D6.06c Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN07/07H02Orfeome Localization Data
UniProtKB/SwissProtO14199UDP-N-acetylglucosamine transferase subunit alg14
ModBaseO14199Database of comparative protein structure models
STRINGO14199Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593363UDP-GlcNAc transferase associated protein Alg14 (predicted)
RefSeq mRNANM_001018795972h- UDP-GlcNAc transferase associated protein Alg14 (predicted) (alg14), mRNA
European Nucleotide ArchiveCAB10854.1ENA Protein Mapping
UniParcUPI000013AA18UniProt Archive

Literature for alg14

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014