SPAC5H10.04

Gene Standard NameUnassigned ChromosomeI
Systematic IDSPAC5H10.04 Gene Start152851
Synonyms Gene End155515
ProductNADPH dehydrogenase (predicted) Gene Length2665
Feature Typeprotein coding CDS Start153387
Name Description CDS End154535
Characterisation Statusconserved_unknown CDS Length1149

Ensembl Gene Location
  1. SPAC11D3.18c
  2. SPNCRNA.612
  3. SPAC5H10.01
  4. SPAC5H10.02c
  5. SPNCRNA.613
  6. SPAC5H10.03
  7. SPRRNA.10
  8. SPAC5H10.04
  9. SPAC5H10.05c
  10. adh4
  11. SPAC5H10.07
  12. pan6
  13. SPAC5H10.09c
  14. SPNCRNA.614
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPAC5H10.04delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003959NADPH dehydrogenase activityIEAEC:1.6.99.1GO_REF:0000003
GO:0010181FMN bindingIEAIPR001155GO_REF:0000002
GO:0018548pentaerythritol trinitrate reductase activityIEAEC:1.6.99.1GO_REF:0000003
GO:0052690trichloro-p-hydroquinone reductive dehalogenase activityIEAEC:1.6.99.1GO_REF:0000003
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1152851155515

References

Region Start End Reference
three_prime_UTR154536155515PMID:21511999
five_prime_UTR152851153386PMID:21511999
three_prime_UTR154536155515PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00724 IPR001155 Pfam NADH:flavin oxidoreductase/NADH oxidase, N-terminal 6 353 3
G3DSA:3.20.20.70 IPR013785 Gene3D 6 376 35
SSF51395 SuperFamily 2 375 10
PTHR22893:SF10 hmmpanther 1 382 2
PTHR22893 hmmpanther 1 382 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.69 Da
Charge 10.00
Isoelectric point 8.92
Molecular weight 43.81 kDa
Number of residues 382
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide0.041PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.26PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
csn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
epe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:22681890
ppk14serine/threonine protein kinase Ppk14 (predicted) Negative GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
sre2membrane-tethered transcription factor (predicted) Negative GeneticPMID:21504829
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Positive GeneticPMID:22681890
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
fml1ATP-dependent 3' to 5' DNA helicase, FANCM ortholog Fml1 Negative GeneticPMID:22681890
SPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:22681890
Negative GeneticPMID:21504829
prp1U4/U6 x U5 tri-snRNP complex subunit Prp1 Positive GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
SPAP14E8.02FHA domain protein Tos4 (predicted) Negative GeneticPMID:22681890
msh3MutS protein homolog 3 Negative GeneticPMID:22681890
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
SPBC15C4.06cubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
swd3WD repeat protein Swd3 Negative GeneticPMID:22681890
SPCC1322.02sequence orphan Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
tas3RITS complex subunit 3 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPAC5H10.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC5H10.04 Retrieval of eukaryotic orthologs
BioGrid SPAC5H10.04 BioGRID Interaction Datasets
Bähler Lab SPAC5H10.04 Cell Cycle Expression Profile
Bähler Lab SPAC5H10.04 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC5H10.04 Pheromone response/mating expression profiles
Bähler Lab SPAC5H10.04 Environmental stress expression profiles
Bähler Lab SPAC5H10.04 Bähler Lab Transcriptome Viewer
Cyclebase SPAC5H10.04 Cell Cycle Data
PInt SPAC5H10.04 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC5H10.04 Entrez Gene
IntEnz1.6.99.1
WikiGene2541543NADPH dehydrogenase (predicted)
EntrezGene2541543NADPH dehydrogenase (predicted)
SPD / RIKEN18/18B05Orfeome Localization Data
UniProtKB/SwissProtQ09670Putative NADPH dehydrogenase C5H10.04
ModBaseQ09670Database of comparative protein structure models
Pfam Protein DomainsQ09670Pfam Domain Arrangement
RefSeq PeptideNP_592817NADPH dehydrogenase (predicted)
RefSeq PeptideNP_592818FAD binding oxidoreductase (predicted)
RefSeq mRNANM_001018217972h- NADPH dehydrogenase (predicted) (SPAC5H10.04), mRNA
RefSeq mRNANM_001018218972h- FAD binding oxidoreductase (predicted) (SPAC5H10.05c), mRNA
European Nucleotide ArchiveCAA89954ENA Protein Mapping
UniParcUPI0000130F8EUniProt Archive

Literature for SPAC5H10.04
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013