SPAC5H10.05c


Gene Standard NameUnassigned Characterisation Statusconserved unknown
Systematic IDSPAC5H10.05c Feature Typeprotein coding
Synonyms Name Description
ProductFAD binding oxidoreductase (predicted) Product Size196aa, 22.10 kDa
Genomic Location Chromosome I, 155583-153070 (2514nt); CDS:155397-154807 (591nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
flavin adenine dinucleotide binding32
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2302
Annotation ExtensionEvidenceWith/FromReference
nucleus2691
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationSPAC5H10.05cΔ3844

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell, abnormal cell shape, normal cell sizeSPAC5H10.05cΔ215
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons155583..153070
mRNA155583..153070
5' UTR155583..155398PMID:21511999
CDS155397..154807
3' UTR154806..153070PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02525 Pfam IPR003680 Flavodoxin-like fold 1 181 1
PTHR10204:SF36 HMMPANTHER 1 191 1
PTHR10204 HMMPANTHER 1 191 1
3.40.50.360 Gene3D IPR029039 Flavoprotein-like domain 1 192 7
SSF52218 SuperFamily IPR029039 Flavoprotein-like domain 1 192 7

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.78 Da
Charge 0.50
Codon Adaptation Index 0.40
Isoelectric point 6.63
Molecular weight 22.10 kDa
Number of residues 196
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPAC5H10.05c

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
21001during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
21860during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
17187during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
18089during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
20089.48during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
18391during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.2during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.27during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
possible horizontal transfer19
Taxonomic Conservation
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog601
Orthologs

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC5H10.05c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bypir2zf-C2H2 type zinc finger protein, implicated in RNAi (predicted) Affinity Capture-MSPMID:24713849
binds DNA-binding domain construct withspa2cell polarity protein Spa2 Two-hybridPMID:26771498
binds activation domain construct withSPAC5H10.05cFAD binding oxidoreductase (predicted) Two-hybridPMID:26771498
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPAC5H10.05c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withpar1protein phosphatase PP2A regulatory subunit B-56 Par1 Positive GeneticPMID:22681890
positive genetic interaction withkin1microtubule affinity-regulating kinase Kin1 Positive GeneticPMID:22681890
negative genetic interaction withtos4FHA domain protein Tos4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvps35retromer complex subunit Vps35 Negative GeneticPMID:22681890
negative genetic interaction withatg6autophagy associated beclin family protein Atg6 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC5H10.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC5H10.05c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC5H10.05c BioGRID Interaction Datasets
Expression Viewer SPAC5H10.05c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC5H10.05c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC5H10.05c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC5H10.05c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC5H10.05c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC5H10.05c Transcriptome Viewer (Bähler Lab)
GEO SPAC5H10.05c GEO profiles
PInt SPAC5H10.05c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC5H10.05c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC5H10.05c Fission yeast phenotypic data & analysis
Cyclebase SPAC5H10.05c.1 Cell Cycle Data
SPD / RIKEN06/06E01Orfeome Localization Data
UniProtKB/SwissProtQ09677Uncharacterized protein C5H10.05c
ModBaseQ09677Database of comparative protein structure models
STRINGQ09677Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_592818FAD binding oxidoreductase (predicted)
RefSeq mRNANM_001018218972h- FAD binding oxidoreductase (predicted) (SPAC5H10.05c), mRNA
European Nucleotide ArchiveCAA89955.1ENA Protein Mapping
UniParcUPI0000139EFCUniProt Archive

Literature for SPAC5H10.05c

Search: Europe PMC or PubMed

Release Version: PomBase:30_60 - 12 May 2016