btn1 (SPAC607.09c)

Gene Standard Namebtn1 ChromosomeI
Systematic IDSPAC607.09c Gene Start2051731
Synonyms Gene End2050462
Productbattenin CLN3 family protein Gene Length1270
Feature Typeprotein coding CDS Start2051652
Name Description CDS End2050462
Characterisation Statuspublished CDS Length1191

Ensembl Gene Location
  1. rpn9
  2. SPAC607.06c
  3. SPAC607.07c
  4. SPAC607.08c
  5. btn1
  6. SPNCRNA.186
  7. spo3
  8. SPNCRNA.790
  9. vma11
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000082sensitive to high temperatureno_name (unrecorded)unrecordedPMID:18346214
FYPO:0002060viable vegetative cell populationMicroscopybtn1delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:16291725
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0006897endocytosisIMPPMID:18346214
GO:0007033vacuole organizationIMPPMID:16291725
GO:0007035vacuolar acidificationIMPPMID:16291725
IGIypt7PMID:16291725
GO:0015802basic amino acid transportISOSGD:S000003595GO_REF:0000024
GO:0031580membrane raft distributionIMPPMID:18346214
GO:0032465regulation of cytokinesisIMPPMID:16291725
GO:0034605cellular response to heatIMPPMID:18346214
GO:0034613cellular protein localization
has_input myo1IMPPMID:18346214
GO:0045324late endosome to vacuole transportIMPPMID:16291725
GO:0051666actin cortical patch localizationIMPPMID:18346214
GO Cellular Component

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0000329fungal-type vacuole membraneIDAPMID:16291725
GO:0005737cytoplasmIDAPMID:18346214
GO:0005783endoplasmic reticulumIDAPMID:16823372
GO:0030176integral to endoplasmic reticulum membraneICGO:0016021, GO:0005783GO_REF:0000001
GO:0032153cell division site
exists_during cellular response to heatIDAPMID:18346214
GO:0051286cell tipIDAPMID:18346214
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
120517312050462

References

Region Start End Reference
five_prime_UTR20517312051653PMID:20118936
five_prime_UTR20517312051653PMID:20118936
five_prime_UTR20517312051653PMID:18641648
five_prime_UTR20517312051653PMID:18641648
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF02487 IPR003492 Pfam Batten's disease protein Cln3 14 384 1
TMhelix TMHMM 76 93 955
TMhelix TMHMM 219 238 955
TMhelix TMHMM 292 314 955
TMhelix TMHMM 13 35 955
TMhelix TMHMM 45 67 955
TMhelix TMHMM 127 149 955
TMhelix TMHMM 319 341 955
TMhelix TMHMM 156 178 955
SSF103473 IPR016196 SuperFamily 23 377 74
PIRSF015974 IPR018460 PIRSF Batten's disease protein Cln3, subgroup 1 389 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 269 284 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 317 341 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 47 63 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 102 124 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 225 247 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 132 152 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 16 38 1
PR01315 IPR003492 PRINTS Batten's disease protein Cln3 353 382 1
PTHR10981 IPR003492 hmmpanther Batten's disease protein Cln3 9 396 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00437farnesylated residueevidenceInferred from Sequence or Structural Similarity

Sequence Ontology

Term IDTerm NameReference
SO:0001812transmembrane_helix

Protein Properties

Ave. residue weight 111.15 Da
Charge 9.50
Isoelectric point 8.62
Molecular weight 44.01 kDa
Number of residues 396
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide515.85PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.56PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
Complementation
DescriptionQualifierReference
functionally complemented by human CLN3 PMID:16291725
Disease Association
DescriptionQualifierReference
neurological disorders
Batten's disease
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
vma1V-type ATPase V1 domain, subunit A Synthetic LethalityPMID:16291725
ypt7GTPase Ypt7 Phenotypic SuppressionPMID:16291725
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
ypt7GTPase Ypt7 Co-localizationPMID:16291725
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External References
Database Identifier Description
NBRP SPAC607.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC607.09c Retrieval of eukaryotic orthologs
BioGrid SPAC607.09c BioGRID Interaction Datasets
Bähler Lab SPAC607.09c Cell Cycle Expression Profile
Bähler Lab SPAC607.09c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC607.09c Pheromone response/mating expression profiles
Bähler Lab SPAC607.09c Environmental stress expression profiles
Bähler Lab SPAC607.09c Bähler Lab Transcriptome Viewer
Cyclebase SPAC607.09c Cell Cycle Data
PInt SPAC607.09c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC607.09c Entrez Gene
WikiGene2543645battenin CLN3 family protein
Uniprot_genenameBTN1
EntrezGene2543645battenin CLN3 family protein
SPD / RIKEN18/18H12Orfeome Localization Data
UniProtKB/SwissProtQ9US09Protein btn1
ModBaseQ9US09Database of comparative protein structure models
Pfam Protein DomainsQ9US09Pfam Domain Arrangement
RefSeq PeptideNP_593598battenin CLN3 family protein
RefSeq mRNANM_001019029972h- battenin CLN3 family protein (btn1), mRNA
European Nucleotide ArchiveCAB63796ENA Protein Mapping
UniParcUPI000006A030UniProt Archive

Literature for btn1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013