spo3 (SPAC607.10)


Gene Standard Namespo3 Characterisation Statuspublished
Systematic IDSPAC607.10 Feature Typeprotein coding
Synonyms Name Description
Productsporulation protein Spo3 Product Size1028aa, 119.41 kDa
Genomic Location Chromosome I, 2052799-2057177 (4379nt); CDS:2053945-2057031 (3087nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
ascospore formation76
Annotation ExtensionEvidenceWith/FromReference
ascospore-type prospore assembly20
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
plasma membrane249
Annotation ExtensionEvidenceWith/FromReference
prospore membrane28
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationspo3ΔNull3781

Cell Phenotype

Term NameAlleleExpressionCount
abnormal forespore membrane formationspo3ΔNull25
abnormal sporulation resulting in formation of ascus containing anucleate sporesspo3Not specified9
abolished sporulationspo3Not specified52
spo3-B3Not specified
spo3ΔNull
normal meiosisspo3-B3Not specified139
normal mitotic spindle pole bodyspo3Not specified9
spindle pole body absent from cell after meiosis IIspo3Not specified9
viable vegetative cell with normal cell morphology3092
penetrance FYPO_EXT:0000001spo3ΔNull
Target Of
OntologyRelationshipGeneProductReference
FYPO affected by mutation in npg1 GTPase regulator Rng2-like (predicted) PMID:25146394
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
120527992057177

UTRs

Region Coordinates Reference
five_prime_UTR2052799..2053944PMID:21511999
three_prime_UTR2057032..2057177PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
SignalP-noTM signalp 1 19 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279

Protein Properties

Ave. residue weight 116.16 Da
Charge 2.50
Isoelectric point 6.75
Molecular weight 119.41 kDa
Number of residues 1028
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreased during GO:0034293experimental evidencePMID:PMPB:0

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.1during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.25during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
Schizosaccharomyces specific220
Orthologs

Orthologs in Compara


Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
npg1GTPase regulator Rng2-like (predicted) Phenotypic EnhancementPMID:25146394
dma1mitotic spindle checkpoint ubiquitin ligase Dma1 Phenotypic EnhancementPMID:20980623
psy1SNARE Psy1 Phenotypic SuppressionPMID:11739793
res1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC607.10 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC607.10 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC607.10 BioGRID Interaction Datasets
Expression Viewer SPAC607.10 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC607.10 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC607.10 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC607.10 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC607.10 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC607.10 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC607.10 Cell Cycle Data
GEO SPAC607.10 GEO profiles
PInt SPAC607.10 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC607.10 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC607.10 Fission yeast phenotypic data & analysis
SPD / RIKEN29/29H12Orfeome Localization Data
UniProtKB/SwissProtQ9US08Sporulation-specific protein 3
ModBaseQ9US08Database of comparative protein structure models
STRINGQ9US08Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593599sporulation protein Spo3
RefSeq mRNANM_001019030972h- sporulation protein Spo3 (spo3), mRNA
European Nucleotide ArchiveCAB63797.1ENA Protein Mapping
UniParcUPI0000135E5AUniProt Archive

Literature for spo3

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015