spo3 (SPAC607.10)

Gene Standard Namespo3 Characterisation Statuspublished
Systematic IDSPAC607.10 Feature Typeprotein coding
Synonyms Name Description
Productsporulation protein Spo3 Product Size1028aa, 119.41 kDa
Genomic Location Chromosome I, 2052799-2057177 (4379nt); CDS:2053945-2057031 (3087nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030437ascospore formationIMPPMID:344282499
GO:0031321ascospore-type prospore assembly20
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005886plasma membraneIEAUniProtKB-KW:KW-1003GO_REF:0000037243
GO:0005628prospore membraneIDAPMID:1173979323
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyspo3ΔNullPECO:0000005, PECO:0000137PMID:236978063755

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000583abolished sporulationMicroscopyspo3Not specifiedPMID:141741725
Microscopyspo3-B3Not specifiedPMID:3442824
FYPO:0000478normal meiosisMicroscopyspo3-B3Not specifiedPMID:344282412
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopyspo3ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
Low complexity (SEG) seg 85 100
Low complexity (SEG) seg 243 261
Low complexity (SEG) seg 540 551
Low complexity (SEG) seg 810 821
Low complexity (SEG) seg 927 939
SignalP-noTM signalp 1 19 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 116.16 Da
Charge 2.50
Isoelectric point 6.75
Molecular weight 119.41 kDa
Number of residues 1028
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.25during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
1.1during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
identified in S. pombe only370
sequence orphan360
no apparent orthologs356
sequence orphan, characterised61

Orthologs in Compara

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dma1mitotic spindle checkpoint ubiquitin ligase Dma1 Phenotypic EnhancementPMID:20980623
psy1SNARE Psy1 Phenotypic SuppressionPMID:11739793
res1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC607.10 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC607.10 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC607.10 BioGRID Interaction Datasets
Expression Viewer SPAC607.10 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC607.10 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC607.10 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC607.10 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC607.10 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC607.10 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC607.10 Cell Cycle Data
GEO SPAC607.10 GEO profiles
PInt SPAC607.10 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2543520sporulation protein Spo3
EntrezGene2543520sporulation protein Spo3
SPD / RIKEN29/29H12Orfeome Localization Data
UniProtKB/SwissProtQ9US08Sporulation-specific protein 3
ModBaseQ9US08Database of comparative protein structure models
StringQ9US08Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593599sporulation protein Spo3
RefSeq mRNANM_001019030972h- sporulation protein Spo3 (spo3), mRNA
European Nucleotide ArchiveCAB63797ENA Protein Mapping
UniParcUPI0000135E5AUniProt Archive

Literature for spo3

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014