gyp7 (SPAC630.05)

Gene Standard Namegyp7 ChromosomeI
Systematic IDSPAC630.05 Gene Start353783
Synonyms Gene End356580
ProductGTPase activating protein Gyp7 (predicted) Gene Length2798
Feature Typeprotein coding CDS Start353900
Name Description CDS End356131
Characterisation Statusbiological_role_inferred CDS Length2232

Ensembl Gene Location
  1. efg1
  2. SPAC12G12.01c
  3. SPAC630.04c
  4. arp3
  5. SPAC630.06c
  6. gyp7
  7. SPAC630.07c
  8. SPNCRNA.641
  9. erg25
  10. SPNCRNA.642
  11. mug177
  12. mug58
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopygyp7delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005097Rab GTPase activator activityISMPFAM:PF00566GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0016192vesicle-mediated transportISOSGD:S000002393GO_REF:0000024
GO:0032313regulation of Rab GTPase activityISMPFAM:PF00566GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1353783356580

References

Region Start End Reference
three_prime_UTR356132356580PMID:21511999
five_prime_UTR353783353899PMID:21511999
three_prime_UTR356132356580PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00566 IPR000195 Pfam Rab-GTPase-TBC domain 415 655 13
SM00164 IPR000195 SMART Rab-GTPase-TBC domain 408 658 13
PS50086 IPR000195 Prosite Profiles Rab-GTPase-TBC domain 411 633 13
G3DSA:1.10.8.270 Gene3D 407 559 12
SSF47923 IPR000195 SuperFamily 385 593 13
SSF47923 IPR000195 SuperFamily 568 691 13
PTHR22957:SF34 hmmpanther 148 743 1
PTHR22957 hmmpanther 148 743 12

View domain organization at Pfam

Protein Properties

Ave. residue weight 116.82 Da
Charge -17.50
Isoelectric point 5.13
Molecular weight 86.79 kDa
Number of residues 743
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2597.64PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1079.63PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.4PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.2PMID:23101633
expression microarray evidenceincreasedPMID:22840777
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
prp1U4/U6 x U5 tri-snRNP complex subunit Prp1 Positive GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:22681890
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
mid1medial ring protein Mid1 Negative GeneticPMID:22681890
SPBC1861.07elongin C (predicted) Positive GeneticPMID:22681890
SPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
pst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
atg6beclin family protein, involved in autophagy Negative GeneticPMID:22681890
fft3fun thirty related protein Fft3 Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPAC630.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC630.05 Retrieval of eukaryotic orthologs
BioGrid SPAC630.05 BioGRID Interaction Datasets
Bähler Lab SPAC630.05 Cell Cycle Expression Profile
Bähler Lab SPAC630.05 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC630.05 Pheromone response/mating expression profiles
Bähler Lab SPAC630.05 Environmental stress expression profiles
Bähler Lab SPAC630.05 Bähler Lab Transcriptome Viewer
Cyclebase SPAC630.05 Cell Cycle Data
PInt SPAC630.05 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC630.05 Entrez Gene
SPD / RIKEN38/38A11Orfeome Localization Data
WikiGene2543609GTPase activating protein Gyp7 (predicted)
Uniprot_genenameGYP7
EntrezGene2543609GTPase activating protein Gyp7 (predicted)
UniProtKB/SwissProtQ9UUH7GTPase-activating protein gyp7
ModBaseQ9UUH7Database of comparative protein structure models
Pfam Protein DomainsQ9UUH7Pfam Domain Arrangement
RefSeq PeptideNP_592900GTPase activating protein Gyp7 (predicted)
RefSeq mRNANM_001018300972h- GTPase activating protein Gyp7 (predicted) (gyp7), mRNA
European Nucleotide ArchiveCAB52727ENA Protein Mapping
UniParcUPI000006ADB6UniProt Archive

Literature for gyp7
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013