bdf2 (SPAC631.02)


Gene Standard Namebdf2 Characterisation Statuspublished
Systematic IDSPAC631.02 Feature Typeprotein coding
Synonymsnrc1 Name DescriptionNegative Regulator of Condensin
ProductBET family double bromodomain protein Bdf2 Product Size727aa, 81.03 kDa
Genomic Location Chromosome I, 2105472-2110519 (5048nt); CDS:2107940-2110123 (2184nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
chromatin binding29
Annotation ExtensionEvidenceWith/FromReference
nucleosomal histone binding4
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
chromatin remodeling156
Annotation ExtensionEvidenceWith/FromReference
negative regulation of extent of heterochromatin assembly2
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nuclear chromatin309
Annotation ExtensionEvidenceWith/FromReference
nucleus2695
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to cadmiumbdf2ΔNull246
viable vegetative cell populationbdf2ΔNull3795

Cell Phenotype

Term NameAlleleExpressionCount
decreased RNA level during vegetative growth146
affecting emc5bdf2ΔNull
heterochromatin assembly beyond boundary element IRC1Rbdf2ΔNull3
heterochromatin assembly beyond boundary element IRC3Lbdf2ΔNull1
heterochromatin assembly beyond boundary element IRRbdf2ΔNull1
increased gene silencing3
affecting emc5bdf2ΔNull
viable vegetative cell with normal cell morphologybdf2ΔNull3093
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2105472..2107367, 2107882..2110519
mRNA2105472..2110519
5' UTR2105472..2107367, 2107882..2107939PMID:21511999
CDS2107940..2110123
3' UTR2110124..2110519PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00439 Pfam IPR001487 Bromodomain 397 481 9
PF00439 Pfam IPR001487 Bromodomain 241 318 9
SM00297 SMART IPR001487 Bromodomain 227 337 9
SM00297 SMART IPR001487 Bromodomain 390 499 9
PS50014 Prosite Profiles IPR001487 Bromodomain 408 480 9
PS50014 Prosite Profiles IPR001487 Bromodomain 246 318 9
PS51525 Prosite Profiles IPR027353 NET domain 570 650 2
PS00633 Prosite Patterns IPR018359 Bromodomain, conserved site 413 472 7
PTHR22880 HMMPANTHER 40 726 4
1.20.920.10 Gene3D IPR001487 Bromodomain 216 352 10
1.20.920.10 Gene3D IPR001487 Bromodomain 387 500 10
SSF47370 SuperFamily IPR001487 Bromodomain 224 340 10
SSF47370 SuperFamily IPR001487 Bromodomain 386 505 10
Coil ncoils Rabaptin coiled-coil domain 537 558 968
PR00503 PRINTS IPR001487 Bromodomain 249 262 9
PR00503 PRINTS IPR001487 Bromodomain 443 461 9
PR00503 PRINTS IPR001487 Bromodomain 461 480 9
PR00503 PRINTS IPR001487 Bromodomain 427 443 9

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000496bromodomainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000496

Protein Properties

Ave. residue weight 111.46 Da
Charge -12.00
Isoelectric point 5.45
Molecular weight 81.03 kDa
Number of residues 727
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS667 1672
present during mitotic M phaseS135
present during mitotic M phaseS133
present during mitotic M phaseS667
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S133 PMID:21712547
present during mitotic M phase experimental evidence S135 PMID:21712547
experimental evidence S667 PMID:24763107
present during mitotic M phase experimental evidence S667 PMID:21712547
O-phospho-L-threonine 698
present during mitotic M phaseT669
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence T669 PMID:21712547
phosphorylated residue 1926
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
467during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
494during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
2421.36during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
593during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
2704.39during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
7.2during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
2.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Disease Association
DescriptionQualifierReferenceCount
cancercancer_census142
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999432
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturesanp1mannosyltransferase complex subunit, Anp family (predicted) Affinity Capture-MSPMID:24013502
affinity capturesapl4AP-1 adaptor complex gamma subunit Apl4 Affinity Capture-MSPMID:24013502
affinity capturesarp9SWI/SNF and RSC complex subunit Arp9 Affinity Capture-MSPMID:24013502
affinity capturesbdf1Swr1 complex bromodomain subunit Brf1 Affinity Capture-MSPMID:24013502
affinity capturesbrf1transcription factor TFIIIB complex subunit Brf1 Affinity Capture-MSPMID:24013502
affinity capturescgs1cAMP-dependent protein kinase regulatory subunit Cgs1 Affinity Capture-MSPMID:24013502
affinity capturescho2phosphatidylethanolamine N-methyltransferase Cho2 Affinity Capture-MSPMID:24013502
affinity capturescka1serine/threonine protein kinase Cka1 Affinity Capture-MSPMID:24013502
affinity capturesckb1CK2 family regulatory subunit Ckb1 Affinity Capture-MSPMID:24013502
affinity capturescnd2condensin complex non-SMC subunit Cnd2 Affinity Capture-MSPMID:24013502
affinity capturescwf22splicing factor Cwf22 Affinity Capture-MSPMID:24013502
affinity capturesdbp5cytoplasmic ATP-dependent RNA helicase Dbp5 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesdbp9ATP-dependent RNA helicase Dbp9 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesddx27ATP-dependent RNA helicase Ddx27/Drs1 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesdhx29ATP-dependent RNA helicase, human DHX29 ortholog (predicted) Affinity Capture-MSPMID:24013502
affinity capturesdnf1Trans-golgi network aminophospholipid translocase (flippase), Dnf1 (predicted) Affinity Capture-MSPMID:24013502
affinity captured byepe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-WesternPMID:24013502
affinity captured byepe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
binds activation domain construct withepe1Jmjc domain chromatin associated protein Epe1 Two-hybridPMID:24013502
affinity capturesepe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
affinity captureserp5COPII vesicle coat component Erp5/Erp6 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesfml2ATP-dependent 3' to 5' DNA helicase (predicted) Affinity Capture-MSPMID:24013502
binds to peptidehhf1histone H4 h4.1 Protein-peptidePMID:24013502
binds to peptidehht1histone H3 h3.1 Protein-peptidePMID:24013502
binds to peptidehta1histone H2A alpha Protein-peptidePMID:24013502
binds to peptidehtb1histone H2B Htb1 Protein-peptidePMID:24013502
affinity captureskin1microtubule affinity-regulating kinase Kin1 Affinity Capture-MSPMID:24013502
affinity capturesmcm2MCM complex subunit Mcm2 Affinity Capture-MSPMID:24013502
affinity capturesmms19Dos2 silencing complex subunit Mms19 Affinity Capture-MSPMID:24013502
affinity capturesnap2nucleosome assembly protein Nap2 Affinity Capture-MSPMID:24013502
affinity capturespmk1MAP kinase Pmk1 Affinity Capture-MSPMID:24013502
affinity capturespsm1mitotic cohesin complex subunit Psm1 Affinity Capture-MSPMID:24013502
affinity capturesptr6transcription factor TFIID complex subunit Taf7 Affinity Capture-MSPMID:24013502
affinity capturesrer2cis-prenyltransferase Affinity Capture-MSPMID:24013502
affinity capturesrmn1RNA-binding protein Affinity Capture-MSPMID:24013502
affinity capturesrnp24RNA-binding protein Rnp24 Affinity Capture-MSPMID:24013502
affinity capturesrpb1RNA polymerase II large subunit Rpb1 Affinity Capture-MSPMID:24013502
affinity capturesrpc1DNA-directed RNA polymerase III complex large subunit Rpc1 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesrpc19DNA-directed RNA polymerase I and III subunit Rpc19 Affinity Capture-MSPMID:24013502
affinity capturesrpc37DNA-directed RNA polymerase III complex subunit Rpc37 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesrrp2ATP-dependent DNA helicase, ubiquitin-protein ligase E3 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesrrp9U3 snoRNP-associated protein Rrp9 (predicted) Affinity Capture-MSPMID:24013502
affinity capturessac11inositol polyphosphate phosphatase (predicted) Affinity Capture-MSPMID:24013502
affinity capturessnf21ATP-dependent DNA helicase Snf21 Affinity Capture-MSPMID:24013502
affinity capturessnt2Lid2 complex subunit Snt2 Affinity Capture-MSPMID:24013502
affinity capturesSPAC11D3.02cELLA family acetyltransferase (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPAC11D3.04cpolyketide cyclase SnoaL-like domain protein Affinity Capture-MSPMID:24013502
affinity capturesSPAC25B8.12cnucleotide-sugar phosphatase (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPAC27F1.06cFKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPAC5H10.03phosphoglycerate mutase family Affinity Capture-MSPMID:24013502
affinity capturesSPAC683.02czf-CCHC type zinc finger protein (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPBC1683.03ctransmembrane transporter (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPBC30D10.14dienelactone hydrolase family (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPCC1223.01ubiquitin-protein ligase E3 (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPCC18.05cnotchless-like protein (predicted) Affinity Capture-MSPMID:24013502
affinity capturesSPCC1827.05cnucleolar RNA-binding protein NIFK (predicted) Affinity Capture-MSPMID:24013502
affinity capturesspo15sporulation protein Spo15 Affinity Capture-MSPMID:24013502
affinity capturesspt5DSIF transcription elongation factor complex subunit Spt5 Affinity Capture-MSPMID:24013502
affinity capturesspt6nucleosome remodeling protein Spt6 Affinity Capture-MSPMID:24013502
affinity capturesssr3SWI/SNF and RSC complex subunit Ssr3 Affinity Capture-MSPMID:24013502
affinity capturestaf10SAGA complex/transcription factor TFIID complex subunit Taf10 Affinity Capture-MSPMID:24013502
affinity capturestaf11transcription factor TFIID complex subunit Taf11 (predicted) Affinity Capture-MSPMID:24013502
affinity capturestaf111transcription factor TFIID complex subunit Taf111 Affinity Capture-MSPMID:24013502
affinity capturestaf2TATA-binding protein associated factor Taf2 (predicted) Affinity Capture-MSPMID:24013502
affinity capturestaf4transcription factor TFIID complex subunit Taf4 (predicted) Affinity Capture-MSPMID:24013502
affinity capturestaf5SAGA complex subunit/TATA-binding protein associated factor/transcription factor TFIID complex subunit Taf5 Affinity Capture-MSPMID:24013502
affinity capturestaf6histone H4-like TAF Taf6, SAGA complex subunit Affinity Capture-MSPMID:24013502
affinity capturestaf73transcription factor TFIID complex subunit Taf5-like Affinity Capture-MSPMID:24013502
affinity capturestaf9SAGA complex/ transcription initiation factor Taf9 Affinity Capture-MSPMID:24013502
affinity capturestif224translation initiation factor eIF2B delta subunit (predicted) Affinity Capture-MSPMID:24013502
affinity capturestma23ribosome biogenesis protein Tma23 (predicted) Affinity Capture-MSPMID:24013502
affinity capturestop2DNA topoisomerase II Affinity Capture-MSPMID:24013502
affinity capturestpp2tripeptidyl-peptidase II Tpp2 Affinity Capture-MSPMID:24013502
affinity capturesuaf2U2AF small subunit, U2AF-23 Affinity Capture-MSPMID:24013502
affinity capturesubp15ubiquitin C-terminal hydrolase Ubp15 Affinity Capture-MSPMID:24013502
affinity capturesubp2ubiquitin C-terminal hydrolase Ubp2 Affinity Capture-MSPMID:24013502
affinity capturesutp14U3 snoRNP protein Utp14 (predicted) Affinity Capture-MSPMID:24013502
affinity captureszhf1zinc ion transmembrane transporter Zhf1 Affinity Capture-MSPMID:24013502
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withago1argonaute Negative GeneticPMID:18818364
negative genetic interaction withago1argonaute Negative GeneticPMID:22681890
negative genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
enhances phenotype ofalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Phenotypic EnhancementPMID:19547744
negative genetic interaction withalp16gamma tubulin complex subunit Alp16 Negative GeneticPMID:18818364
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:18818364
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
negative genetic interaction withash2Ash2-trithorax family protein Negative GeneticPMID:22681890
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
positive genetic interaction withatp11mitochondrial F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withaut12autophagy associated protein Aut12 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withbdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:18818364
synthetic lethal withbdf1Swr1 complex bromodomain subunit Brf1 Synthetic LethalityPMID:22095079
negative genetic interaction withbdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:22681890
negative genetic interaction withbob1prefoldin subunit 5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withbyr2MAP kinase kinase kinase Byr2 Negative GeneticPMID:18818364
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
synthetic growth defect withcds1replication checkpoint kinase Cds1 Synthetic Growth DefectPMID:22095079
synthetically rescuescds1replication checkpoint kinase Cds1 Synthetic RescuePMID:22095079
synthetically rescueschk1Chk1 protein kinase Synthetic RescuePMID:22095079
synthetic growth defect withchk1Chk1 protein kinase Synthetic Growth DefectPMID:22095079
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:18818364
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
synthetically rescuescrb2DNA repair protein Rad9 homolog Crb2 Synthetic RescuePMID:22095079
negative genetic interaction withcwf15complexed with Cdc5 protein Cwf15 Negative GeneticPMID:22681890
negative genetic interaction withcwf19complexed with Cdc5 protein Cwf19 Negative GeneticPMID:22681890
negative genetic interaction withcwf28splicing factor Cwf28 Negative GeneticPMID:22681890
negative genetic interaction withcwf5RNA-binding protein Cwf5 Negative GeneticPMID:22681890
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:18818364
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:18818364
negative genetic interaction withdad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
negative genetic interaction withdad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
negative genetic interaction withdam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
negative genetic interaction withdcr1dicer Negative GeneticPMID:18818364
negative genetic interaction withdcr1dicer Negative GeneticPMID:22681890
negative genetic interaction withdim1U4/U6 x U5 tri-snRNP complex subunit Dim1 Negative GeneticPMID:22681890
negative genetic interaction withduo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withelp3elongator complex subunit Elp3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:18818364
negative genetic interaction withfta6Mis6-Sim4 complex Fta6 Negative GeneticPMID:22681890
negative genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:18818364
negative genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:22681890
negative genetic interaction withgim1prefoldin subunit 6, Gim1 (predicted) Negative GeneticPMID:18818364
rescued byhhf1histone H4 h4.1 Phenotypic SuppressionPMID:24013502
negative genetic interaction withhif2Set3 complex subunit Hif2 Negative GeneticPMID:18818364
negative genetic interaction withhos2histone deacetylase (class I) Hos2 Negative GeneticPMID:18818364
negative genetic interaction withhos2histone deacetylase (class I) Hos2 Negative GeneticPMID:22681890
positive genetic interaction withhrp3ATP-dependent DNA helicase Hrp3 Positive GeneticPMID:18818364
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:18818364
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:18818364
negative genetic interaction withlsc1Lsk1 associated cyclin Negative GeneticPMID:22681890
negative genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:18818364
negative genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:22681890
negative genetic interaction withmcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:18818364
negative genetic interaction withmcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:22681890
negative genetic interaction withmed7mediator complex subunit Med7 Negative GeneticPMID:18818364
negative genetic interaction withmed7mediator complex subunit Med7 Negative GeneticPMID:22681890
negative genetic interaction withmms19Dos2 silencing complex subunit Mms19 Negative GeneticPMID:18818364
negative genetic interaction withmph1dual specificity protein kinase Mph1 Negative GeneticPMID:18818364
negative genetic interaction withmpr1histidine-containing response regulator phosphotransferase Mpr1 Negative GeneticPMID:22681890
synthetically rescuesmrc1mediator of replication checkpoint 1 Synthetic RescuePMID:22095079
synthetic growth defect withmrc1mediator of replication checkpoint 1 Synthetic Growth DefectPMID:22095079
rescuesmrc1mediator of replication checkpoint 1 Phenotypic SuppressionPMID:22095079
negative genetic interaction withmsc1multi-copy suppressor of Chk1 Negative GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:18818364
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withngg1SAGA complex subunit Ngg1 Negative GeneticPMID:18818364
negative genetic interaction withngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
negative genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withnup132nucleoporin Nup132 Negative GeneticPMID:22681890
negative genetic interaction withpab2poly(A) binding protein Pab2 Negative GeneticPMID:18818364
negative genetic interaction withpab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
negative genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withpar1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:18818364
negative genetic interaction withpar1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:22681890
negative genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:18818364
negative genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:18818364
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
negative genetic interaction withpmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:18818364
negative genetic interaction withpmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:22681890
negative genetic interaction withpob3FACT complex subunit Pob3 Negative GeneticPMID:18818364
negative genetic interaction withpob3FACT complex subunit Pob3 Negative GeneticPMID:22681890
negative genetic interaction withpom1DYRK family protein kinase Pom1 Negative GeneticPMID:22681890
negative genetic interaction withprp24RNA-binding protein Prp24 Negative GeneticPMID:22681890
negative genetic interaction withprw1Clr6 histone deacetylase complex subunit Prw1 Negative GeneticPMID:22681890
negative genetic interaction withpyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
synthetic growth defect withrad3ATR checkpoint kinase Rad3 Synthetic Growth DefectPMID:22095079
synthetically rescuesrad3ATR checkpoint kinase Rad3 Synthetic RescuePMID:22095079
negative genetic interaction withrap1telomere binding protein Rap1 Negative GeneticPMID:18818364
positive genetic interaction withres2MBF transcription factor complex subunit Res2 Positive GeneticPMID:18818364
positive genetic interaction withres2MBF transcription factor complex subunit Res2 Positive GeneticPMID:22681890
negative genetic interaction withrhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:18818364
negative genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:18818364
negative genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withrox3mediator complex subunit Med19/Rox3 Negative GeneticPMID:18818364
negative genetic interaction withrox3mediator complex subunit Med19/Rox3 Negative GeneticPMID:22681890
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
negative genetic interaction withrpb9DNA-directed RNA polymerase II complex subunit Rpb9 Negative GeneticPMID:18818364
negative genetic interaction withrpb9DNA-directed RNA polymerase II complex subunit Rpb9 Negative GeneticPMID:22681890
negative genetic interaction withrxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
negative genetic interaction withsap114U2 snRNP subunit Sap114 Negative GeneticPMID:22681890
positive genetic interaction withscs7sphingosine hydroxylase Scs7 Positive GeneticPMID:18818364
negative genetic interaction withsdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:18818364
negative genetic interaction withsdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:22681890
negative genetic interaction withset11ribosomal protein lysine methyltransferase Set11 Negative GeneticPMID:18818364
negative genetic interaction withset11ribosomal protein lysine methyltransferase Set11 Negative GeneticPMID:22681890
negative genetic interaction withset3histone lysine methyltransferase Set3 Negative GeneticPMID:18818364
negative genetic interaction withset3histone lysine methyltransferase Set3 Negative GeneticPMID:22681890
negative genetic interaction withsgf29SAGA complex subunit Sgf29 Negative GeneticPMID:18818364
rescuessir2Sirtuin family histone deacetylase Sir2 Phenotypic SuppressionPMID:24013502
negative genetic interaction withsnu66U4/U6 x U5 tri-snRNP complex subunit Snu66 Negative GeneticPMID:22681890
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:18818364
negative genetic interaction withSPBC1861.07elongin C (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
negative genetic interaction withspc34DASH complex subunit Spc34 Negative GeneticPMID:18818364
negative genetic interaction withspc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
negative genetic interaction withSPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:18818364
negative genetic interaction withspf30splicing factor Spf30 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsrp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
negative genetic interaction withssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsty1MAP kinase Sty1 Negative GeneticPMID:22681890
negative genetic interaction withswc2Swr1 complex complex subunit Swc2 Negative GeneticPMID:18818364
negative genetic interaction withswc5Swr1 complex subunit Swc5 Negative GeneticPMID:18818364
negative genetic interaction withswd3WD repeat protein Swd3 Negative GeneticPMID:22681890
synthetically rescuesswi1replication fork protection complex subunit Swi1 Synthetic RescuePMID:22095079
negative genetic interaction withswr1SNF2 family ATP-dependent DNA helicase Swr1 Negative GeneticPMID:18818364
negative genetic interaction withswr1SNF2 family ATP-dependent DNA helicase Swr1 Negative GeneticPMID:22681890
negative genetic interaction withtps1alpha,alpha-trehalose-phosphate synthase Negative GeneticPMID:22681890
negative genetic interaction withura5orotate phosphoribosyltransferase Ura5 Negative GeneticPMID:18818364
negative genetic interaction withusp109U1 snRNP-associated protein Usp109 Negative GeneticPMID:22681890
negative genetic interaction withvps35retromer complex subunit Vps35 Negative GeneticPMID:22681890
negative genetic interaction withvps5retromer complex subunit Vps5 Negative GeneticPMID:22681890
negative genetic interaction withvps71Swr1 complex subunit Vps71 Negative GeneticPMID:18818364
negative genetic interaction withvrp1verprolin Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC631.02 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC631.02 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC631.02 BioGRID Interaction Datasets
Expression Viewer SPAC631.02 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC631.02 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC631.02 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC631.02 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC631.02 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC631.02 Transcriptome Viewer (Bähler Lab)
GEO SPAC631.02 GEO profiles
PInt SPAC631.02 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC631.02 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC631.02 Fission yeast phenotypic data & analysis
Cyclebase SPAC631.02.1 Cell Cycle Data
SPD / RIKEN39/39F08Orfeome Localization Data
UniProtKB/SwissProtQ9HGP4Bromodomain-containing protein C631.02
ModBaseQ9HGP4Database of comparative protein structure models
STRINGQ9HGP4Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593620bromodomain protein (predicted)
European Nucleotide ArchiveD89157ENA EMBL mapping
European Nucleotide ArchiveCAC05484.3ENA Protein Mapping
UniParcUPI00000695BEUniProt Archive

Literature for bdf2

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Release Version: PomBase:26_51 - 07 Apr 2015