SPAC631.02

Synonyms ChromosomeI
Productbromodomain protein (predicted) Gene Start2105472
Feature Typeprotein coding Gene End2110519
Name Description CDS Start2107940
Characterisation Statusbiological_role_inferred CDS End2110123

Ensembl Gene Location
fft3 SPAC25A8.02 acp2 > SPAC631.02 < utp5 SPNCRNA.795 dsc3 tfs1
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
121054722107367
221078822110519

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF00439 Pfam Bromodomain 397 481 76.9 9
PF00439 Pfam Bromodomain 241 318 71.1 9
47370 Superfamily 208 348 121.9 9
47370 Superfamily 366 510 126.7 9
SM00297 Smart Bromodomain 390 499 164.4 9
SM00297 Smart Bromodomain 227 337 129.1 9
PS50014 PROSITE Bromodomain 246 318 19.813 9
PS50014 PROSITE Bromodomain 408 480 19.385 9
PS00633 scanprosite Bromodomain 413 472 7
PR00503 Prints Bromodomain 249 262 41.93 9
PR00503 Prints Bromodomain 427 443 53.84 9
PR00503 Prints Bromodomain 443 461 26.2 9
PR00503 Prints Bromodomain 461 480 38.15 9


Protein Modifications

Term IDDescriptionSourceAll Genes
MOD:00696phosphorylated residueTemporary processing gif - replaced by AJAX with count of genes annotated with the term MOD:00696

Protein Properties

Ave. residue weight 111.46 Da
Charge -12.00
Isoelectric point 5.45
Molecular weight 81.03 kDa
Number of residues 727
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

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Biological Process
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0006338chromatin remodelingISS SGD:S000004391GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006338

Cellular Component
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000790nuclear chromatinISS PFAM:PF00439GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000790
GO:0005634nucleusISS SGD:S000004391GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005634
IDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year reference

Disease Association

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DescriptionSourceAll Genes
cancerTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000239

Warning

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DescriptionSourceAll Genes
gene structure updated Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000070

Protein Family

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DescriptionSourceAll Genes
bromodomainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000496

Species Distribution

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DescriptionSourceAll Genes
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in Eukaryotes onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000096
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094

Manually Curated Orthologs

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SpeciesGeneDescription

Interactions

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Genetic Interactions from BioGRID

Gene Feature Evidence Source
SPBC337.03RNA polymerase II transcription termination factor (predicted) Negative Genetic
sdc1Dpy-30 domain protein Sdc1 Negative Genetic
rok1ATP-dependent RNA helicase Rok1 (predicted) Negative Genetic
fin1serine/threonine protein kinase, NIMA related Fin1 Negative Genetic
rap1telomere binding protein Rap1 Negative Genetic
mph1dual specificity protein kinase Mph1 Negative Genetic
mcl1DNA polymerase alpha accessory factor Mcl1 Negative Genetic
SPCC1919.13cribosome biogenesis protein (predicted) Negative Genetic
mug154conserved fungal protein Negative Genetic
ago1argonaute Negative Genetic
alp16gamma tubulin complex subunit Alp16 Negative Genetic
spc34DASH complex subunit Spc34 Negative Genetic
aut12autophagy associated protein Aut12 (predicted) Negative Genetic
pmc2mediator complex subunit Pmc2/Med1 Negative Genetic
med7mediator complex subunit Med7 Negative Genetic
SPBC1861.07elongin C (predicted) Negative Genetic
ask1DASH complex subunit Ask1 Negative Genetic
bdf1Swr1 complex bromodomain subunit Brf1 Negative Genetic
spf1Set1C PHD Finger protein Spf1 Negative Genetic
dad2DASH complex subunit Dad2 Negative Genetic
arp42SWI/SNF and RSC complex subunit Arp42 Negative Genetic
dad1DASH complex subunit Dad1 Negative Genetic
set11ribosomal protein lysine methyltransferase Set11 Negative Genetic
swr1SNF2 family helicase Swr1 Negative Genetic
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative Genetic
ngg1SAGA complex subunit Ngg1 Negative Genetic
SPBC36B7.08cnucleosome assembly protein (predicted) Negative Genetic
set3histone lysine methyltransferase Set3 Negative Genetic
pob3FACT complex component Pob3 Negative Genetic
par1protein phosphatase regulatory subunit Par1 Negative Genetic
res2MBF transcription factor complex subunit Res2 Positive Genetic
SPAC3A11.13prefoldin subunit 6 (predicted) Negative Genetic
bob1prefoldin subunit 5 (predicted) Negative Genetic
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative Genetic
rnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative Genetic
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative Genetic
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Phenotypic Enhancement
swc5Swr1 complex subunit Swc5 Negative Genetic
hif2Set3 complex subunit Hif2 Negative Genetic
vps71Swr1 complex subunit Vps71 Negative Genetic
hrp3ATP-dependent DNA helicase Hrp3 Positive Genetic
elp2elongator complex subunit Elp2 (predicted) Positive Genetic
swc2Swr1 complex complex subunit Swc2 Negative Genetic
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative Genetic
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative Genetic
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative Genetic
scs7sphingosine hydroxylase Scs7 Positive Genetic
klp6kinesin-like protein Klp6 Negative Genetic
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative Genetic
hos2histone deacetylase (class I) Hos2 Negative Genetic
pac10prefoldin subunit 3 Pac10 (predicted) Negative Genetic
ura5orotate phosphoribosyltransferase Ura5 Negative Genetic
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative Genetic
rpb9DNA-directed RNA polymerase II complex subunit Rpb9 Negative Genetic
sgf29SAGA complex subunit Sgf29 Negative Genetic
mms19TFIIH regulator Mms19 Negative Genetic
not3CCR4-Not complex subunit Not3/5 (predicted) Negative Genetic
rox3mediator complex subunit Med19/Rox3 Negative Genetic
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative Genetic
pht1histone H2A variant H2A.Z, Pht1 Negative Genetic
dcr1dicer Negative Genetic
pab2poly(A) binding protein Pab2 Negative Genetic
byr2MAP kinase kinase kinase Byr2 Negative Genetic
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative Genetic

Physical Interactions from BioGRID

Gene Feature Evidence Source
stc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-MS

External References

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Database Identifier Description
NBRP SPAC631.02 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC631.02 Retrieval of eukaryotic orthologs
BioGrid SPAC631.02 BioGRID Interaction Datasets
Bähler Lab SPAC631.02 Cell Cycle Expression Profile
Bähler Lab SPAC631.02 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC631.02 Pheromone response/mating expression profiles
Bähler Lab SPAC631.02 Environmental stress expression profiles
Bähler Lab SPAC631.02 Bähler Lab Transcriptome Viewer
Cyclebase SPAC631.02 Cell Cycle Data
Entrez Gene SPAC631.02 Link to Entrez Gene
SPD / RIKEN39/39F08Orfeome Localization Data
UniProtKB/SwissProtQ9HGP4Bromodomain-containing protein C631.02
ArrayExpressQ9HGP4Link to ArrayExpress
RefSeq PeptideNP_593620bromodomain protein
RefSeq mRNANM_001019051972h- bromodomain protein (SPAC631.02), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveD89157ENA EMBL mapping
European Nucleotide ArchiveBAA13819ENA Protein Mapping
European Nucleotide ArchiveCAC05484ENA Protein Mapping
UniParcUPI00000695BEUniProt Archive

Literature for SPAC631.02

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Search: UK PMC or PubMed