rlp7 (SPAC664.06)


Gene Standard Namerlp7 Characterisation Statusbiological_role_inferred
Systematic IDSPAC664.06 Feature Typeprotein coding
Synonymsrpl7, rpl7-3, rpl703 Name Description
Productribosomal protein L7-like Rlp7 involved in ribosome biogenesis (predicted) Product Size249aa, 29.17 kDa
Genomic Location Chromosome I, 1712784-1713921 (1138nt); CDS:1712817-1713783 (967nt)

Ensembl Gene Location
GO Biological Process

GO Slim Terms

ribosome biogenesis


Term NameCount
ribosomal large subunit biogenesis41
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nucleolus343
Annotation ExtensionEvidenceWith/FromReference
preribosome, large subunit precursor15
Annotation ExtensionEvidenceWith/FromReference
ribosome283
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyrlp7ΔNullPMID:204732891338
Microscopyrlp7ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002151inviable spore465
penetrance FYPO_EXT:0000001Microscopyrlp7ΔNullPECO:0000005, PECO:0000137PMID:23697806
Target Of
OntologyRelationshipGeneProductReference
FYPO affected by mutation in dbr1 RNA lariat debranching enzyme Dbr1 PMID:9001235
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
117127841712939
217131571713921

UTRs

Region Coordinates Reference
five_prime_UTR1712784..1712816PMID:21511999
three_prime_UTR1713784..1713921PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF08079 Pfam IPR012988 Ribosomal protein L30, N-terminal 18 86 3
PF00327 Pfam IPR016082 Ribosomal protein L30, ferredoxin-like fold domain 89 140 4
PS00634 Prosite Patterns IPR018038 Ribosomal protein L30, conserved site 108 140 3
PTHR11524 HMMPANTHER 13 249 3
3.30.1390.20 Gene3D IPR016082 Ribosomal protein L30, ferredoxin-like fold domain 90 145 4
3.30.1390.20 Gene3D IPR016082 Ribosomal protein L30, ferredoxin-like fold domain 209 247 4
SSF55129 SuperFamily IPR016082 Ribosomal protein L30, ferredoxin-like fold domain 89 248 4
Coil ncoils Rabaptin coiled-coil domain 23 51 968
TIGR01310 tigrfam IPR005998 Ribosomal protein L7, eukaryotic 15 248 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 117.13 Da
Charge 24.50
Isoelectric point 10.76
Molecular weight 29.17 kDa
Number of residues 249
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA leveldecreased in presence of methyl methanesulfonate expression microarray evidencePMID:12529438
decreased during GO:0034605expression microarray evidencePMID:12529438
decreased during GO:0071470expression microarray evidencePMID:12529438
decreased during GO:0034599expression microarray evidencePMID:12529438
decreased in presence of cadmium sulfate expression microarray evidencePMID:12529438

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
19037during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
19999during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
20003during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
19892during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
18259during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
14236.5during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
5421.45during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
18during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
4.3during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
ncRNA in intron16
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4600
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3425
conserved in vertebrates3400
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC664.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC664.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC664.06 BioGRID Interaction Datasets
Expression Viewer SPAC664.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC664.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC664.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC664.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC664.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC664.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC664.06 Cell Cycle Data
GEO SPAC664.06 GEO profiles
PInt SPAC664.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC664.06 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC664.06 Fission yeast phenotypic data & analysis
SPD / RIKEN13/13G06Orfeome Localization Data
UniProtKB/SwissProtP1793760S ribosomal protein L7-A
ModBaseP17937Database of comparative protein structure models
STRINGP17937Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593454ribosome biogenesis protein rlp7
RefSeq mRNANM_001018887972h- ribosome biogenesis protein rlp7 (rlp7), mRNA
European Nucleotide ArchiveCAA37639.1ENA Protein Mapping
European Nucleotide ArchiveCAB65807.1ENA Protein Mapping
UniParcUPI0000134187UniProt Archive

Literature for rlp7

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014