set13 (SPAC688.14)

Gene Standard Nameset13 ChromosomeI
Systematic IDSPAC688.14 Gene Start3141223
Synonyms Gene End3143183
Productribosome L32 lysine methyltransferase Set13 Gene Length1961
Feature Typeprotein coding CDS Start3141463
Name Description CDS End3143034
Characterisation Statuspublished CDS Length1572

Ensembl Gene Location
  1. end4
  2. SPNCRNA.888
  3. SPNCRNA.889
  4. SPAC688.12c
  5. scn1
  6. SPNCRNA.890
  7. set13
  8. SPAC688.16
  9. SPNCRNA.891
  10. bet5
  11. fcf2
  12. sak1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopyset13delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0016279protein-lysine N-methyltransferase activity
has_direct_input rpl42IDAPMID:20444689
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006479protein methylationIDAPMID:20444689
GO:0043555regulation of translation in response to stressIMPPMID:20444689
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
IDAPMID:20444689
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
131412233141603
231416523142329
331423963142667
431427193143183

References

Region Start End Reference
three_prime_UTR31430353143183PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00856 IPR001214 Pfam SET domain 37 302 12
G3DSA:3.90.1410.10 Gene3D 255 316 5
G3DSA:3.90.1410.10 Gene3D 4 185 5
SSF82199 SuperFamily 4 187 13
SSF82199 SuperFamily 257 320 13
PIRSF011771 IPR011383 PIRSF RuBisCO-cytochrome methylase, RMS1 1 468 1
PTHR13271 hmmpanther 2 466 5

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0001327SET domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001327

Protein Properties

Ave. residue weight 115.43 Da
Charge -19.50
Isoelectric point 4.68
Molecular weight 54.02 kDa
Number of residues 468
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.35PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide1.3PMID:23101633
Warning
DescriptionQualifierReference
gene structure updated PMID:21511999
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
ppk9serine/threonine protein kinase Ppk9 (predicted) Positive GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:18818364
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
pof4elongin-A, F-box protein Pof4 (predicted) Positive GeneticPMID:18818364
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:18818364
raf1Rik1-associated factor Raf1 Positive GeneticPMID:18818364
SPAC19A8.11crecombination protein Irc6 (predicted) Negative GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Positive GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
rpl4260S ribosomal protein L36/L42 Biochemical ActivityPMID:20444689
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External References
Database Identifier Description
NBRP SPAC688.14 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC688.14 Retrieval of eukaryotic orthologs
BioGrid SPAC688.14 BioGRID Interaction Datasets
Bähler Lab SPAC688.14 Cell Cycle Expression Profile
Bähler Lab SPAC688.14 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC688.14 Pheromone response/mating expression profiles
Bähler Lab SPAC688.14 Environmental stress expression profiles
Bähler Lab SPAC688.14 Bähler Lab Transcriptome Viewer
Cyclebase SPAC688.14 Cell Cycle Data
PInt SPAC688.14 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC688.14 Entrez Gene
WikiGene2543346lysine methyltransferase (predicted)
Uniprot_genenameSET13
EntrezGene2543346lysine methyltransferase (predicted)
SPD / RIKEN25/25B03Orfeome Localization Data
UniProtKB/SwissProtQ9P6L2Ribosomal N-lysine methyltransferase 4
ModBaseQ9P6L2Database of comparative protein structure models
Pfam Protein DomainsQ9P6L2Pfam Domain Arrangement
RefSeq PeptideNP_594072lysine methyltransferase (predicted)
RefSeq mRNANM_001019496972h- lysine methyltransferase (predicted) (SPAC688.14), mRNA
European Nucleotide ArchiveCAB90780ENA Protein Mapping
SPD / RIKEN25/25B03Orfeome Localization Data

Literature for set13
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013