tom70 (SPAC6B12.12)


Gene Standard Nametom70 Characterisation Statusbiological_role_inferred
Systematic IDSPAC6B12.12 Feature Typeprotein coding
Synonyms Name Description
Productmitochondrial TOM complex subunit Tom70 (predicted) Product Size625aa, 69.52 kDa
Genomic Location Chromosome I, 2433332-2435623 (2292nt); CDS:2433392-2435269 (1878nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein transporter activity41
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
protein import into mitochondrial inner membrane12
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
integral component of membrane1018
Annotation ExtensionEvidenceWith/FromReference
mitochondrial outer membrane translocase complex6
Annotation ExtensionEvidenceWith/FromReference
mitochondrion761
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
abolished cell population growth on glycerol carbon sourcetom70ΔNull67
decreased mating efficiencytom70ΔNull249
decreased vegetative cell population growthtom70ΔNull472
sensitive to cadmiumtom70ΔNull246
sensitive to hydrogen peroxidetom70ΔNull137
sensitive to salt stresstom70ΔNull88
slow vegetative cell population growthtom70ΔNull321
viable vegetative cell populationtom70ΔNull3792

Cell Phenotype

Term NameAlleleExpressionCount
decreased protein level during cellular response to hypoxia3
affecting sre1tom70+ (wild type)Overexpression
decreased transcription from SRE promotertom70+ (wild type)Overexpression3
elongated telomerestom70ΔNull167
increased cellular pigment accumulation during cellular response to cadmium ion14
colour PATO:0000324tom70ΔNull
viable vegetative cell with normal cell morphologytom70ΔNull3092
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2433332..2435623
mRNA2433332..2435623
5' UTR2433332..2433391PMID:21511999
CDS2433392..2435269
3' UTR2435270..2435623PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF13414 Pfam 534 588 18
PF13414 Pfam 150 214 18
PF00515 Pfam IPR001440 Tetratricopeptide TPR1 416 447 13
PF07719 Pfam IPR013105 Tetratricopeptide TPR2 484 514 8
SM00028 SMART IPR019734 Tetratricopeptide repeat 415 448 26
SM00028 SMART IPR019734 Tetratricopeptide repeat 523 557 26
SM00028 SMART IPR019734 Tetratricopeptide repeat 558 591 26
SM00028 SMART IPR019734 Tetratricopeptide repeat 483 516 26
SM00028 SMART IPR019734 Tetratricopeptide repeat 151 184 26
SM00028 SMART IPR019734 Tetratricopeptide repeat 449 482 26
SM00028 SMART IPR019734 Tetratricopeptide repeat 347 380 26
SM00028 SMART IPR019734 Tetratricopeptide repeat 185 217 26
TMhelix TMHMM 32 51 959
PS50005 Prosite Profiles IPR019734 Tetratricopeptide repeat 558 591 23
PS50005 Prosite Profiles IPR019734 Tetratricopeptide repeat 184 217 23
PS50005 Prosite Profiles IPR019734 Tetratricopeptide repeat 483 516 23
PS50005 Prosite Profiles IPR019734 Tetratricopeptide repeat 381 414 23
PS50005 Prosite Profiles IPR019734 Tetratricopeptide repeat 449 482 23
PS50005 Prosite Profiles IPR019734 Tetratricopeptide repeat 415 448 23
PS50005 Prosite Profiles IPR019734 Tetratricopeptide repeat 347 380 23
PS50293 Prosite Profiles IPR013026 Tetratricopeptide repeat-containing domain 184 238 27
PS50293 Prosite Profiles IPR013026 Tetratricopeptide repeat-containing domain 347 591 27
PS50293 Prosite Profiles IPR013026 Tetratricopeptide repeat-containing domain 151 184 27
PTHR22904 HMMPANTHER 68 621 8
PTHR22904:SF304 HMMPANTHER 68 621 1
1.25.40.10 Gene3D IPR011990 Tetratricopeptide-like helical domain 442 502 62
1.25.40.10 Gene3D IPR011990 Tetratricopeptide-like helical domain 346 441 62
1.25.40.10 Gene3D IPR011990 Tetratricopeptide-like helical domain 148 240 62
1.25.40.10 Gene3D IPR011990 Tetratricopeptide-like helical domain 503 601 62
SSF48452 SuperFamily 308 423 50
SSF48452 SuperFamily 391 588 50
SSF48452 SuperFamily 150 241 50

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000245TPR repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000245

Protein Properties

Ave. residue weight 111.23 Da
Charge 9.00
Isoelectric point 8.22
Molecular weight 69.52 kDa
Number of residues 625
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS129
present during mitotic M phaseS271
present during mitotic M phaseS272
present during mitotic M phaseS128
present during mitotic M phaseS93
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S93 PMID:21712547
present during mitotic M phase experimental evidence S128 PMID:21712547
present during mitotic M phase experimental evidence S129 PMID:21712547
present during mitotic M phase experimental evidence S271 PMID:21712547
present during mitotic M phase experimental evidence S272 PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
49800during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
48929during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
50755during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
46172during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
16491.47during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
50000during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
11869.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
9.8during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
1.6during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byfic1C2 domain protein Fic1 Affinity Capture-MSPMID:19139265
affinity captured byhhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
affinity captured byhhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
affinity captured byrng2IQGAP Affinity Capture-MSPMID:20603077
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
affinity captured byubp11ubiquitin C-terminal hydrolase Ubp11 Affinity Capture-MSPMID:20838651
affinity captured byubp11ubiquitin C-terminal hydrolase Ubp11 Affinity Capture-WesternPMID:20838651
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withabc4glutathione S-conjugate-exporting ATPase Abc4 Positive GeneticPMID:22681890
positive genetic interaction withaca1L-azetidine-2-carboxylic acid acetyltransferase Aca1 Positive GeneticPMID:22681890
negative genetic interaction withade3phosphoribosylformylglycinamidine synthase Ade3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withadn2transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withadn3transcription factor (predicted) Negative GeneticPMID:22681890
positive genetic interaction withair1zinc knuckle TRAMP complex subunit Air1 Positive GeneticPMID:22681890
positive genetic interaction withalb1pre-60S shuttling factor Alb1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withalg12dolichyl pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase Alg12 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withalg6glucosyltransferase Alg6 Positive GeneticPMID:22681890
positive genetic interaction withalm1medial ring protein Alm1 Positive GeneticPMID:22681890
negative genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
positive genetic interaction withalp16gamma tubulin complex subunit Alp16 Positive GeneticPMID:22681890
negative genetic interaction withamk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:22681890
positive genetic interaction withany1arrestin-related endocytic adaptor Any1 Positive GeneticPMID:22681890
positive genetic interaction withaph1bis(5'-nucleosidyl)-tetraphosphatase Positive GeneticPMID:22681890
positive genetic interaction withapt1adenine phosphoribosyltransferase (APRT) (predicted) Positive GeneticPMID:22681890
negative genetic interaction witharf6ADP-ribosylation factor, Arf family Arf6 Negative GeneticPMID:22681890
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
positive genetic interaction withasp1inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withatf31transcription factor Atf31 Negative GeneticPMID:22681890
positive genetic interaction withatg20sorting nexin Atg20 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatg4Atg8 deconjugator Atg4 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withatg6beclin family protein, involved in autophagy Negative GeneticPMID:22681890
negative genetic interaction withath1ataxin-2 homolog Negative GeneticPMID:22681890
negative genetic interaction withatp11mitochondrial F1-ATPase chaperone Atp11 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withbdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:22681890
negative genetic interaction withbdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:22681890
positive genetic interaction withbio2biotin synthase Positive GeneticPMID:22681890
negative genetic interaction withblt1ubiquitin domain-like protein Blt1 Negative GeneticPMID:22681890
positive genetic interaction withbob1prefoldin subunit 5 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withbop1ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withbtb2BTB/POZ domain protein Btb2 Positive GeneticPMID:22681890
negative genetic interaction withbun107WD repeat protein, human WDR48 family Bun107 Negative GeneticPMID:22681890
negative genetic interaction withbun62WD repeat protein, human WDR20 family, Bun62 Negative GeneticPMID:22681890
positive genetic interaction withcat1cationic amino acid transmembrane transporter Cat1 Positive GeneticPMID:22681890
positive genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withcgi121EKC/KEOPS complex subunit Cgi121 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withcir2mitochondrial electron transfer flavoprotein-ubiquinone oxidoreductase Cir2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withcmk1calcium/calmodulin-dependent protein kinase Cmk1 Negative GeneticPMID:22681890
negative genetic interaction withcmk2MAPK-activated protein kinase Cmk2 Negative GeneticPMID:22681890
negative genetic interaction withcox8cytochrome c oxidase subunit VIII (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
positive genetic interaction withcrb2DNA repair protein Rad9 homolog Crb2 Positive GeneticPMID:22681890
negative genetic interaction withcsi2mitotic chromosome segregation protein Csi2 Negative GeneticPMID:22681890
negative genetic interaction withcsk1cyclin-dependent kinase/ cyclin-dependent kinase activating kinase Csk1 Negative GeneticPMID:22681890
positive genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Positive GeneticPMID:22681890
positive genetic interaction withcta3P-type ATPase, potassium exporting Cta3 Positive GeneticPMID:22681890
positive genetic interaction withctp1CtIP-related endonuclease Positive GeneticPMID:22681890
positive genetic interaction withctu2cytosolic thiouridylase subunit Ctu2 Positive GeneticPMID:22681890
negative genetic interaction withcwf18complexed with Cdc5 protein Cwf18 Negative GeneticPMID:22681890
positive genetic interaction withcyp3cyclophilin family peptidyl-prolyl cis- trans isomerase Cyp3 Positive GeneticPMID:22681890
positive genetic interaction withcyp4cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withcys11cysteine synthase Positive GeneticPMID:22681890
negative genetic interaction withdad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
negative genetic interaction withdad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
positive genetic interaction withdbl6double strand break localizing protein Dbl6 Positive GeneticPMID:22681890
positive genetic interaction withdbl7Schizosaccharomyces specific protein, double strand break localizing Dbl7 Positive GeneticPMID:22681890
positive genetic interaction withdcd1deoxycytidylate deaminase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withdip1WISH/DIP/SPIN90 ortholog Dip1 Negative GeneticPMID:22681890
positive genetic interaction withdmc1RecA family ATPase Dmc1 Positive GeneticPMID:22681890
positive genetic interaction withdoa10ER-localized ubiquitin-protein ligase E3 Doa10 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withdph6diphthamide synthetase Dph6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withdsd1dihydroceramide delta-4 desaturase Positive GeneticPMID:22681890
positive genetic interaction withdsk1SR protein-specific kinase Dsk1 Positive GeneticPMID:22681890
negative genetic interaction withduo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
positive genetic interaction withdus2tRNA dihydrouridine synthase Dus2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction witheif21translation initiation factor eIF2A (predicted) Positive GeneticPMID:22681890
negative genetic interaction witheis1eisosome assembly protein eis1 Negative GeneticPMID:22681890
positive genetic interaction withelp1elongator subunit Elp1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withelp6elongator complex subunit Elp6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withely5nuclear pore protein Ely5 Positive GeneticPMID:22681890
negative genetic interaction witheri1double-strand siRNA ribonuclease Eri1 Negative GeneticPMID:22681890
positive genetic interaction witherp2COPII-coated vesicle component Erp2/3/4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withexg1glucan 1,6-beta-glucosidase Exg1 Positive GeneticPMID:22681890
positive genetic interaction withexg3glucan 1,3-beta-glucosidase Exg3 Positive GeneticPMID:22681890
positive genetic interaction withexo1exonuclease I Exo1 Positive GeneticPMID:22681890
synthetic lethal withfan1Fanconi-associated nuclease Fan1 Synthetic LethalityPMID:24192486
positive genetic interaction withfft1SMARCAD1 family ATP-dependent DNA helicase Fft1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfis1mitochondrial fission protein Fis1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfma1methionine aminopeptidase Fma1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfrp1ferric-chelate reductase Frp1 Positive GeneticPMID:22681890
positive genetic interaction withfsv1SNARE Fsv1 Positive GeneticPMID:22681890
positive genetic interaction withftp105Ubp5 interacting protein Ftp105 Positive GeneticPMID:22681890
positive genetic interaction withgar2nucleolar protein required for rRNA processing Positive GeneticPMID:22681890
negative genetic interaction withght4hexose transmembrane transporter Ght4 Negative GeneticPMID:22681890
positive genetic interaction withgim3prefoldin subunit 4, Gim3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withgma12alpha-1,2-galactosyltransferase Gma12 Negative GeneticPMID:22681890
negative genetic interaction withgmh2alpha-1,2-galactosyltransferase Gmh2 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withgmh4alpha-1,2-galactosyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withgyp51GTPase activating protein Gyp51 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withhcr1translation initiation factor eIF3j (p35) Positive GeneticPMID:22681890
positive genetic interaction withhhp2serine/threonine protein kinase Hhp2 Positive GeneticPMID:22681890
negative genetic interaction withhmt2sulfide-quinone oxidoreductase Negative GeneticPMID:22681890
positive genetic interaction withhob3BAR adaptor protein Hob3 Positive GeneticPMID:22681890
positive genetic interaction withhop1linear element associated protein Hop1 Positive GeneticPMID:22681890
negative genetic interaction withhrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:22681890
positive genetic interaction withhus1checkpoint clamp complex protein Hus1 Positive GeneticPMID:22681890
positive genetic interaction withibp1Cdc25 family phosphatase Ibp1 Positive GeneticPMID:22681890
negative genetic interaction withies4Ino80 complex subunit Ies4 Negative GeneticPMID:22681890
positive genetic interaction withime4mRNA (N6-adenosine)-methyltransferase Ime4 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withjmj2histone demethylase Jmj2 Negative GeneticPMID:22681890
positive genetic interaction withklp2minus end-directed kinesin-14, Klp2 Positive GeneticPMID:22681890
negative genetic interaction withknd1Cullin-associated NEDD8-dissociated protein Knd1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withknk1AAA family ATPase kink, Knk1 Negative GeneticPMID:22681890
negative genetic interaction withlsg1Lsk1 complex gamma subunit Lsg1 Negative GeneticPMID:22681890
positive genetic interaction withlub1WD repeat protein Lub1 Positive GeneticPMID:22681890
positive genetic interaction withlys3saccharopine dehydrogenase Lys3 Positive GeneticPMID:22681890
negative genetic interaction withmag1DNA-3-methyladenine glycosylase Mag1 Negative GeneticPMID:22681890
negative genetic interaction withmak1histidine kinase Mak1 Negative GeneticPMID:22681890
positive genetic interaction withmak10NatC N-acetyltransferase complex subunit Mak10 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmak3histidine kinase Mak3 Positive GeneticPMID:22681890
positive genetic interaction withmal1maltase alpha-glucosidase Mal1 Positive GeneticPMID:22681890
positive genetic interaction withmca1transcription factor, zf-fungal binuclear cluster type Mca1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmcp1microtubule binding protein Mcp1 Positive GeneticPMID:22681890
positive genetic interaction withmei4meiotic forkhead transcription factor Mei4 Positive GeneticPMID:22681890
positive genetic interaction withmet14adenylyl-sulfate kinase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmet8siroheme synthase Met8 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmeu22amino acid transmembrane transporter, predicted Meu22 Positive GeneticPMID:22681890
negative genetic interaction withmeu27UPF0300 family protein 5 Negative GeneticPMID:22681890
positive genetic interaction withmid1medial ring protein Mid1 Positive GeneticPMID:22681890
positive genetic interaction withmis20centromere protein Mis20/Eic2 Positive GeneticPMID:22681890
positive genetic interaction withmlh1MutL family protein Mlh1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withmmb1mitochondrial microtubule binder Mmb1 Negative GeneticPMID:22681890
negative genetic interaction withmms1E3 ubiquitin ligase complex subunit Mms1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmms19Dos2 silencing complex subunit Mms19 Positive GeneticPMID:22681890
positive genetic interaction withmod21gamma tubulin complex subunit Mod21 Positive GeneticPMID:22681890
positive genetic interaction withmok11alpha-1,3-glucan synthase Mok11 Positive GeneticPMID:22681890
positive genetic interaction withmpc1mitochondrial pyruvate transmembrane transporter subunit Mpc1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withmsc1multi-copy suppressor of Chk1 Negative GeneticPMID:22681890
positive genetic interaction withmso1endocytic docking protein Mso1 Positive GeneticPMID:22681890
positive genetic interaction withmss1mitochondrial GTPase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmug10Rho guanine nucleotide exchange factor (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmug117conserved fungal protein Mug117 Positive GeneticPMID:22681890
positive genetic interaction withmug122PX/PXA domain protein Positive GeneticPMID:22681890
positive genetic interaction withmug124Schizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
positive genetic interaction withmug129Schizosaccharomyces specific protein Mug129 Positive GeneticPMID:22681890
negative genetic interaction withmug147Schizosaccharomyces specific protein Mug147 Negative GeneticPMID:22681890
positive genetic interaction withmug150Schizosaccharomyces pombe specific protein Mug150 Positive GeneticPMID:22681890
positive genetic interaction withmug154conserved fungal protein Positive GeneticPMID:22681890
negative genetic interaction withmug166Schizosaccharomyces specific protein Mug166 Negative GeneticPMID:22681890
positive genetic interaction withmug20Schizosaccharomyces specific protein Mug20 Positive GeneticPMID:22681890
negative genetic interaction withmug27meiosis specific protein kinase Mug27/Slk1 Negative GeneticPMID:22681890
negative genetic interaction withmug37conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withmug62AMP binding enzyme (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmug63TLDc domain protein 1 Positive GeneticPMID:22681890
negative genetic interaction withmug65spore wall assembly protein Mug65 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmug81ATP-dependent RNA helicase Slh1, human ASCC3 ortholog (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmug9conserved fungal protein Positive GeneticPMID:22681890
negative genetic interaction withmvp1sorting nexin Mvp1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnap1nucleosome assembly protein Nap1 Negative GeneticPMID:22681890
negative genetic interaction withnfs1mitochondrial cysteine desulfurase Nfs1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withnmt14-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase Nmt1 Positive GeneticPMID:22681890
positive genetic interaction withnop10snoRNP pseudouridylase box H/ACA snoRNP complex protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withnop52nucleolar protein Nop52 family (predicted) Positive GeneticPMID:22681890
positive genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withnrm1MBF complex corepressor Nrm1 Negative GeneticPMID:22681890
positive genetic interaction withnts1Schizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withnud3nuclear distribution protein NUDC homolog Positive GeneticPMID:22681890
positive genetic interaction withnup124nucleoporin Nup124 Positive GeneticPMID:22681890
positive genetic interaction withnup97nucleoporin Nic96 homolog Positive GeneticPMID:22681890
positive genetic interaction withofd22 OG-Fe(II) oxygenase superfamily protein Ofd2 Positive GeneticPMID:22681890
positive genetic interaction withoga1Stm1 homolog Oga1 Positive GeneticPMID:22681890
positive genetic interaction withomh6alpha-1,2-mannosyltransferase Omh6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpab2poly(A) binding protein Pab2 Positive GeneticPMID:22681890
positive genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpar1protein phosphatase regulatory subunit Par1 Positive GeneticPMID:22681890
negative genetic interaction withpdi5protein disulfide isomerase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withpds5mitotic cohesin-associated protein Pds5 Positive GeneticPMID:22681890
positive genetic interaction withpdt1Nramp family manganese ion transmembrane transporter Positive GeneticPMID:22681890
negative genetic interaction withpet127mitochondrial RNA metabolism pathway protein Pet127 Negative GeneticPMID:22681890
negative genetic interaction withpet801mitochondrial S-adenosylmethionine transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpex5peroxisomal targeting signal receptor Pex5 Negative GeneticPMID:22681890
positive genetic interaction withpex6peroxin-6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpfl7cell surface glycoprotein (predicted), DIPSY family Positive GeneticPMID:22681890
positive genetic interaction withpha2phrenate dehydratase Positive GeneticPMID:22681890
negative genetic interaction withphp5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
negative genetic interaction withplb1phospholipase B homolog Plb1 Negative GeneticPMID:22681890
positive genetic interaction withplg7phospholipase A2, PAF family homolog Positive GeneticPMID:22681890
positive genetic interaction withpmp1dual-specificity MAP kinase phosphatase Pmp1 Positive GeneticPMID:22681890
positive genetic interaction withpmr1P-type ATPase, calcium transporting Pmr1 Positive GeneticPMID:22681890
positive genetic interaction withpng2ING family homolog Png2 Positive GeneticPMID:22681890
positive genetic interaction withpnu1mitochondrial endodeoxyribonuclease Pnu1 Positive GeneticPMID:22681890
positive genetic interaction withpof3F-box protein Pof3 Positive GeneticPMID:22681890
positive genetic interaction withpof9F-box protein Pof9 Positive GeneticPMID:22681890
positive genetic interaction withpom1DYRK family protein kinase Pom1 Positive GeneticPMID:22681890
positive genetic interaction withpop2F-box/WD repeat protein Pop2 Positive GeneticPMID:22681890
negative genetic interaction withppe1serine/threonine protein phosphatase Ppe1 Negative GeneticPMID:22681890
negative genetic interaction withppk16serine/threonine protein kinase Ppk16 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withppk21serine/threonine protein kinase Ppk21 Positive GeneticPMID:22681890
positive genetic interaction withppk26protein kinase like PAN complex subunit Ppk26 Positive GeneticPMID:22681890
negative genetic interaction withppk27serine/threonine protein kinase Ppk27 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withppk29Ark1/Prk1 family protein kinase Ppk29 Positive GeneticPMID:22681890
positive genetic interaction withpsk1serine/threonine protein kinase Psk1 Positive GeneticPMID:22681890
negative genetic interaction withptc2protein phosphatase 2C Ptc2 Negative GeneticPMID:22681890
negative genetic interaction withpth1mitochondrial peptidyl-tRNA hydrolase Pth1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withptl2triacylglycerol lipase ptl2 Positive GeneticPMID:22681890
negative genetic interaction withptr2PTR family peptide transmembrane transporter Ptr2 Negative GeneticPMID:22681890
positive genetic interaction withpuf6Puf family RNA-binding protein Puf6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpus3tRNA pseudouridine synthase Pus3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpvg2galactose residue biosynthesis protein Pvg2 Positive GeneticPMID:22681890
positive genetic interaction withpxd1structure-specific DNA nuclease regulator Pxd1 Positive GeneticPMID:22681890
negative genetic interaction withqcr8ubiquinol-cytochrome-c reductase complex subunit 7 Negative GeneticPMID:22681890
positive genetic interaction withrad17RFC related checkpoint protein Rad17 Positive GeneticPMID:22681890
positive genetic interaction withrav1RAVE complex subunit Rav1 Positive GeneticPMID:22681890
positive genetic interaction withrcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Positive GeneticPMID:22681890
negative genetic interaction withrep1MBF transcription factor activator Rep1 Negative GeneticPMID:22681890
positive genetic interaction withrex3exonuclease Rex3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrga3Rho-type GTPase activating protein Rga3 Negative GeneticPMID:22681890
positive genetic interaction withrho3Rho family GTPase Rho3 Positive GeneticPMID:22681890
positive genetic interaction withrmn1RNA-binding protein Positive GeneticPMID:22681890
positive genetic interaction withrmt3type I ribosomal protein arginine N-methyltransferase Rmt3 Positive GeneticPMID:22681890
positive genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Positive GeneticPMID:22681890
positive genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Positive GeneticPMID:22681890
positive genetic interaction withrpl160160S ribosomal protein L13/L16 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl190260S ribosomal protein L19 Positive GeneticPMID:22681890
positive genetic interaction withrpl210260S ribosomal protein L21 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl230160S ribosomal protein L23 Positive GeneticPMID:22681890
positive genetic interaction withrpl240260S ribosomal protein L24 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl250260S ribosomal protein L25 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl270160S ribosomal protein L27 Positive GeneticPMID:22681890
positive genetic interaction withrpl35b60S ribosomal protein L35a (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl370260S ribosomal protein L37 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrpl410160S ribosomal protein L41 Positive GeneticPMID:22681890
positive genetic interaction withrpl430260S ribosomal protein L37a (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrpl4460S ribosomal protein L28/L44 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withrpl70260S ribosomal protein L7 Positive GeneticPMID:22681890
positive genetic interaction withrpp20160S acidic ribosomal protein A2 Positive GeneticPMID:22681890
positive genetic interaction withrpp20360S acidic ribosomal protein A2 Positive GeneticPMID:22681890
positive genetic interaction withrps00140S ribosomal protein S0A (p40) Positive GeneticPMID:22681890
positive genetic interaction withrps10140S ribosomal protein S3a Positive GeneticPMID:22681890
positive genetic interaction withrps110240S ribosomal protein S11 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrps120140S ribosomal protein S12 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrps160240S ribosomal protein S16 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrps170140S ribosomal protein S17 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrps240140S ribosomal protein S24 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrps280240S ribosomal protein S28, Rps2802 Positive GeneticPMID:22681890
negative genetic interaction withrps340S ribosomal protein S3 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withrps40140S ribosomal protein S4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrps40240S ribosomal protein S4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrps40340S ribosomal protein S4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrrg1protein-lysine N-methyltransferase Rrg1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrrp1ATP-dependent DNA helicase/ ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrrp16rRNA processing protein Rrp16 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrtf2replication termination factor Rtf2 Negative GeneticPMID:22681890
positive genetic interaction withsaf5splicing factor Saf5 Positive GeneticPMID:22681890
negative genetic interaction withsap14U2 snRNP-associated protein SF3B14 Sap14 Negative GeneticPMID:22681890
positive genetic interaction withsck2serine/threonine protein kinase Sck2 Positive GeneticPMID:24463365
positive genetic interaction withsck2serine/threonine protein kinase Sck2 Positive GeneticPMID:22681890
positive genetic interaction withscs7sphingosine hydroxylase Scs7 Positive GeneticPMID:22681890
negative genetic interaction withsdh3succinate dehydrogenase (ubiquinone) cytochrome b subunit (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Negative GeneticPMID:22681890
positive genetic interaction withsdu1PPPDE peptidase family (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsec63ER protein translocation subcomplex subunit Sec63 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withsep1forkhead transcription factor Sep1 Negative GeneticPMID:22681890
negative genetic interaction withset11ribosomal protein lysine methyltransferase Set11 Negative GeneticPMID:22681890
positive genetic interaction withsfp1transcription factor Sfp1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withsgf29SAGA complex subunit Sgf29 Negative GeneticPMID:22681890
negative genetic interaction withshy1cytochrome c oxidase assembly protein Shy1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withsib1ferrichrome synthetase Sib1 Positive GeneticPMID:22681890
positive genetic interaction withsib2ornithine N5 monooxygenase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsif3Sad1 interacting factor Sif3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withskb5Shk1 kinase binding protein 5 Positive GeneticPMID:22681890
negative genetic interaction withsnd1RNA-binding protein, involved in chromatin silencing by small RNA, Snd1 Negative GeneticPMID:22681890
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
positive genetic interaction withsno1glutamine aminotransferase subunit Sno1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsnz1pyridoxine biosynthesis protein Positive GeneticPMID:22681890
negative genetic interaction withSPAC105.02cankyrin repeat protein, implicated in meiosis Negative GeneticPMID:22681890
negative genetic interaction withSPAC10F6.14cABC1 kinase family protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC11H11.03cATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity implicated in DNA repair (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC139.01cnuclease, XP-G family (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC1399.02transmembrane transporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC13G6.09SSU-rRNA maturation protein Tsr4 homolog 2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC15A10.06CPA1 sodium ion/proton antiporter (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1687.21phosphoglycerate mutase family (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1952.09cacetyl-CoA hydrolase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC1B3.02ctranscription elongation factor, Elf1 family (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1B3.04cmitochondrial GTPase involved in translation Guf1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC1B3.08COP9 signalosome complex subunit 12 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1B3.10cSEL1 repeat protein, unknown biological role Negative GeneticPMID:22681890
positive genetic interaction withSPAC222.13c6-phosphofructo-2-kinase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC23A1.14cuncharacterised trans-sulfuration enzyme (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC23C4.05cLEA domain protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC23G3.05cregulator of G-protein signaling (RGS) domain (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC26A3.11amidohydrolase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC26A3.14cDUF1748 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC29A4.02ctranslation elongation factor EF-1 gamma subunit Positive GeneticPMID:22681890
negative genetic interaction withSPAC29A4.17cmitochondrial FUN14 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPAC29B12.12helper of TIM (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC29E6.07Schizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPAC2C4.06ctRNA (cytosine-5-)-methyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC2E1P3.05cfungal cellulose binding domain protein Positive GeneticPMID:22681890
positive genetic interaction withSPAC2F3.11exopolyphosphatase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC30C2.04cofactor for methionyl-and glutamyl-tRNA synthetases (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC3A12.06csodium/calcium exchanger (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC3H8.04possible chromosome segregation protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC3H8.08ctranscription factor (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC4C5.01haloacid dehalogenase-like hydrolase Positive GeneticPMID:22681890
positive genetic interaction withSPAC4F10.16cP-type ATPase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC4G8.08mitochondrial iron ion transmembrane transporter (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC4H3.03cglucan 1,4-alpha-glucosidase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC57A10.08ccarboxylic ester hydrolase activity (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC57A7.13RNA-binding protein, involved in splicing (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC5H10.01DUF1445 family protein Positive GeneticPMID:22681890
positive genetic interaction withSPAC5H10.07Schizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPAC688.03chuman AMMECR1 homolog Positive GeneticPMID:22681890
positive genetic interaction withSPAC694.02DEAD/DEAH box helicase Positive GeneticPMID:22681890
positive genetic interaction withSPAC6G9.01cconserved protein Positive GeneticPMID:22681890
positive genetic interaction withSPAC750.04cS. pombe specific 5Tm protein family Positive GeneticPMID:22681890
positive genetic interaction withSPAC750.06cS. pombe specific DUF999 protein family 4 Positive GeneticPMID:22681890
positive genetic interaction withSPAC869.02cnitric oxide dioxygenase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC8C9.05D-Tyr-tRNA deacylase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC9.02cpolyamine N-acetyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC977.11CRCB domain protein Positive GeneticPMID:22681890
negative genetic interaction withSPAC977.15dienelactone hydrolase family Negative GeneticPMID:22681890
positive genetic interaction withSPAP8A3.07cphospho-2-dehydro-3-deoxyheptonate aldolase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAP8A3.13cVid24 family protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAPB1E7.11cSchizosaccharomyces specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPAPB24D3.08cNADP-dependent oxidoreductase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAPB2C8.01cell surface glycoprotein, adhesion molecule (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAPB8E5.08Schizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPAPB8E5.10conserved fungal protein, with meiosis specific splicing Positive GeneticPMID:22681890
positive genetic interaction withSPAPJ695.01cS. pombe specific UPF0321 family protein 3 Positive GeneticPMID:22681890
positive genetic interaction withSPBC106.12cTHO complex subunit (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC106.13ubiquitin ligase complex subunit, involved in proteasome-dependent catabolite inactivation of FBPase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC115.03gfo/idh/mocA family oxidoreductase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC11B10.08WW domain containing conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC1271.03cNLI interacting factor family phosphatase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC1271.05czf-AN1 type zinc finger protein Positive GeneticPMID:22681890
positive genetic interaction withSPBC1271.14glutamate N-acetyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC1348.01S. pombe specific DUF999 protein family 5 Positive GeneticPMID:22681890
negative genetic interaction withSPBC1348.10cphospholipase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC14C8.11cSchizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC14C8.15triglyceride lipase-cholesterol esterase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC16C6.03cribosome assembly protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC16C6.05mitochondrial translation initiation factor (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC16E9.02cCUE domain protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC16H5.12cconserved fungal protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Positive GeneticPMID:22681890
positive genetic interaction withSPBC1778.05chuman LAMTOR2 ortholog Positive GeneticPMID:22681890
positive genetic interaction withSPBC1778.09GTPase activating protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC17A3.06phosphoprotein phosphatase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC17A3.08TatD homolog (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC18H10.18cSchizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPBC1921.04cdubious Positive GeneticPMID:22681890
positive genetic interaction withSPBC1E8.02ubiquitin family protein (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC20F10.03conserved eukaryotic protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC215.01GTPase activating protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC21B10.08cantibiotic biosynthesis monooxygenase-like domain (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC21C3.06Schizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC25B2.10Usp (universal stress protein) family protein Positive GeneticPMID:22681890
positive genetic interaction withSPBC25H2.03vacuolar protein involved in phosphoinositide metabolism (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC25H2.09DUF1690 family protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC25H2.15SSU-rRNA maturation protein Tsr4 homolog 1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC28E12.02RNA-binding protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC28E12.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC30D10.05csepiapterin reductase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC31F10.03ChaC-like protein, predicted cation transport regulator Negative GeneticPMID:22681890
positive genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC32H8.01cconserved fungal protein, involved in endocytic trafficking (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC359.01amino acid transmembrane transporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC3B8.05diphthamide biosynthesis protein Dph1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC3E7.05chuman mitofilin ortholog (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC3E7.11cDNAJ protein Caj1/Djp1-type (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC418.02NatA N-acetyltransferase complex subunit (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC4C3.09acetylglucosaminyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC543.02cDNAJ/TPR domain protein DNAJC7 family Positive GeneticPMID:22681890
positive genetic interaction withSPBC660.17cSchizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withSPBC713.03mitochondrial D-lactate dehydrogenase, cytochrome (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC800.11inosine-uridine preferring nucleoside hydrolase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC839.02arrestin Aly1 related, implicated in endocytosis Negative GeneticPMID:22681890
positive genetic interaction withSPBC839.03cneddylation protein Dcn1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC947.06cspermidine family transmembrane transporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBP22H7.06nicotinamide riboside kinase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBP35G2.12ADP-ribose diphosphatase, NudF subfamily (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBP4H10.16cphosphatase activator (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBP4H10.18cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
positive genetic interaction withSPBPB10D8.05ctransmembrane transporter (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBPB2B2.09c2-dehydropantoate 2-reductase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBPB2B2.11nucleotide-sugar 4,6-dehydratase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBPB2B2.17cS. pombe specific 5Tm protein family Positive GeneticPMID:22681890
positive genetic interaction withSPBPJ4664.05conserved fungal protein Positive GeneticPMID:22681890
negative genetic interaction withspc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
positive genetic interaction withspc2signal peptidase subunit Spc2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withspc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
negative genetic interaction withSPCC126.08clectin family glycoprotein receptor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1281.07cglutathione S-transferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1450.09cphospholipase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC1620.12cGTPase activating protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC16A11.01plasma membrane protein involved in inositol lipid-mediated signaling Sfk1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC16A11.03cDUF2009 protein Negative GeneticPMID:22681890
positive genetic interaction withSPCC1739.06curoporphyrin methyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC1739.08cshort chain dehydrogenase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC1795.10cSed5 Vesicle Protein Svp26 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC18.17cproteasome assembly chaperone (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC1827.03cacetyl-CoA ligase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC1840.05cphosphoglucomutase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC18B5.05cphosphomethylpyrimidine kinase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC23B6.02cpre-ribosomal factor (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC24B10.16cproteasome assembly chaperone 4 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC320.03transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC330.03cNADPH-hemoprotein reductase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC550.03cSki complex RNA helicase Ski2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPCC550.07acetamidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC569.07aromatic aminotransferase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC584.11cSvf1 family protein Svf1 Positive GeneticPMID:22681890
positive genetic interaction withSPCC61.05S. pombe specific multicopy membrane protein family 1 Positive GeneticPMID:22681890
negative genetic interaction withSPCC613.02transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC63.03DNAJ domain protein, DNAJC11 family Negative GeneticPMID:22681890
positive genetic interaction withSPCC63.06human WDR89 family WD repeat protein Positive GeneticPMID:22681890
negative genetic interaction withSPCC663.09cshort chain dehydrogenase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC663.15cconserved fungal protein Positive GeneticPMID:22681890
positive genetic interaction withSPCC736.02Schizosaccharomyces specific protein Positive GeneticPMID:22681890
negative genetic interaction withSPCC777.04amino acid transmembrane transporter (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPCC794.03amino acid permease (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC965.13pyridoxal family transmembrane transporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCP20C8.02cS. pombe specific UPF0321 family protein 1 Positive GeneticPMID:22681890
negative genetic interaction withSPCP31B10.04conserved fungal protein Negative GeneticPMID:22681890
positive genetic interaction withspd1ribonucleotide reductase (RNR) inhibitor Positive GeneticPMID:22681890
positive genetic interaction withspf31DNAJ protein Spf31 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withspn2mitotic and meiotic (sporulation) septin Spn2 Negative GeneticPMID:22681890
positive genetic interaction withspo20sec14 cytosolic factor family Sec14 Positive GeneticPMID:22681890
positive genetic interaction withspo6Spo4-Spo6 kinase complex regulatory subunit Spo6 Positive GeneticPMID:22681890
positive genetic interaction withspp27RNA polymerase I upstream activation factor complex subunit Spp27 Positive GeneticPMID:22681890
positive genetic interaction withsrb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Positive GeneticPMID:22681890
rescuessre1sterol regulatory element binding protein, transcription factor Sre1 Phenotypic SuppressionPMID:24327658
positive genetic interaction withssr3SWI/SNF and RSC complex subunit Ssr3 Positive GeneticPMID:22681890
positive genetic interaction withste20Rictor homolog, Ste20 Positive GeneticPMID:22681890
negative genetic interaction withstt41-phosphatidylinositol 4-kinase Stt4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsty1MAP kinase Sty1 Negative GeneticPMID:22681890
positive genetic interaction withsua1sulfate adenylyltransferase Positive GeneticPMID:22681890
positive genetic interaction withsum1translation initiation factor eIF3i Positive GeneticPMID:22681890
negative genetic interaction withswc5Swr1 complex subunit Swc5 Negative GeneticPMID:22681890
negative genetic interaction withsyj2inositol-polyphosphate 5-phosphatase, synaptojanin homolog 2 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withtcg1single-stranded telomeric binding protein Tgc1 Positive GeneticPMID:22681890
positive genetic interaction withtea2kinesin-like protein Tea2 Positive GeneticPMID:22681890
positive genetic interaction withtef101translation elongation factor EF-1 alpha Ef1a-a Positive GeneticPMID:22681890
negative genetic interaction withthi4bifunctional thiamine-phosphate dipyrophosphorylase/hydroxyethylthiazole kinase Negative GeneticPMID:22681890
positive genetic interaction withthi5transcription factor Thi5 Positive GeneticPMID:22681890
negative genetic interaction withtif213translation initiation factor eIF2 gamma subunit Negative GeneticPMID:22681890
negative genetic interaction withtim13TIM22 inner membrane protein import complex subunit Tim13 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withtls1splicing factor Tls1 Positive GeneticPMID:22681890
positive genetic interaction withtma20RNA-binding protein Tma20 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtos4FHA domain protein Tos4 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtpp1trehalose-6-phosphate phosphatase Tpp1 Positive GeneticPMID:22681890
negative genetic interaction withtps1alpha,alpha-trehalose-phosphate synthase Negative GeneticPMID:22681890
positive genetic interaction withtps2trehalose-phosphate synthase Tps2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtrm1tRNA (guanine-N2-)-methyltransferase Trm1 Negative GeneticPMID:22681890
positive genetic interaction withtrm112protein and tRNA methyltransferase regulatory subunit Trm112 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtrm12tRNA methyltransferase Trm12 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtrm8tRNA (guanine-N7-)-methyltransferase catalytic subunit Trm8 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtrs8502TRAPP complex subunit Trs85b (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtsf1mitochondrial translation elongation factor EF-Ts Tsf1 Negative GeneticPMID:22681890
positive genetic interaction withtup11transcriptional corepressor Tup11 Positive GeneticPMID:22681890
positive genetic interaction withuba42thiosulfate sulfurtransferase, URM1 activating enzyme E1-type Uba42 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withubx2UBX domain protein Ubx2 Positive GeneticPMID:22681890
positive genetic interaction withuch2ubiquitin C-terminal hydrolase Uch2 Positive GeneticPMID:22681890
negative genetic interaction withucp12ATP-dependent RNA helicase Ucp12 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withura3dihydroorotate dehydrogenase Ura3 Negative GeneticPMID:22681890
positive genetic interaction withurg2uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withutp16U3 snoRNP-associated protein Utp16 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withvms1Cdc48p-Npl4p-Vms1p AAA ATPase complex subunit involved in ER associated ubiquitin-dependent protein catabolic process Vms1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withvps1301chorein homolog Vps13a (predicted) Negative GeneticPMID:22681890
positive genetic interaction withvsl1vacuolar SNARE Vsl1/Vam7 Positive GeneticPMID:22681890
positive genetic interaction withwos2p23 homolog, predicted co-chaperone Wos2 Positive GeneticPMID:22681890
positive genetic interaction withwtf20wtf element Wtf20 Positive GeneticPMID:22681890
negative genetic interaction withwtf21wtf element Wtf21 Negative GeneticPMID:22681890
positive genetic interaction withxks1xylulose kinase Xks1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withyar1ribosome biogenesis protein Yar1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withyea6mitochondrial NAD transmembrane transporter Yea6 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withyip5Rab GTPase binding Yip5 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Positive GeneticPMID:22681890
negative genetic interaction withypt4GTPase Ypt4 Negative GeneticPMID:22681890
positive genetic interaction withzip2vacuolar membrane zinc transmembrane transporter (predicted) Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC6B12.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC6B12.12 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC6B12.12 BioGRID Interaction Datasets
Expression Viewer SPAC6B12.12 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC6B12.12 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC6B12.12 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC6B12.12 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC6B12.12 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC6B12.12 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC6B12.12 Cell Cycle Data
GEO SPAC6B12.12 GEO profiles
PInt SPAC6B12.12 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC6B12.12 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC6B12.12 Fission yeast phenotypic data & analysis
SPD / RIKEN36/36H11Orfeome Localization Data
UniProtKB/SwissProtO14217Probable mitochondrial import receptor subunit tom70
ModBaseO14217Database of comparative protein structure models
STRINGO14217Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593767mitochondrial TOM complex subunit Tom70 (predicted)
RefSeq mRNANM_001019197972h- mitochondrial TOM complex subunit Tom70 (predicted) (tom70), mRNA
European Nucleotide ArchiveCAB11072.1ENA Protein Mapping
UniParcUPI000006B58EUniProt Archive

Literature for tom70

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Release Version: PomBase:25_50 - 10 Mar 2015