cfr1 (SPAC6G9.12)

Gene Standard Namecfr1 ChromosomeI
Systematic IDSPAC6G9.12 Gene Start3270191
Synonyms Gene End3272367
ProductChs five related protein Cfr1 Gene Length2177
Feature Typeprotein coding CDS Start3270235
Name Description CDS End3272097
Characterisation Statuspublished CDS Length1863

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopycfr1delta (deletion)deletionPMID:20473289
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
NOT GO:0006031chitin biosynthetic processIMPPMID:16598689
GO:0006893Golgi to plasma membrane transportISOSGD:S000004322GO_REF:0000024
NOT GO:0009250glucan biosynthetic processIMPPMID:16598689
GO:0032219cell wall macromolecule catabolic process involved in cytogamyIMPPMID:16598689
different_pathwayIGIfus1PMID:16598689
GO:0032220plasma membrane fusion involved in cytogamyIMPPMID:16598689
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0005794Golgi apparatusIDAPMID:16598689
GO:0005829cytosolIDAPMID:16823372
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
132701913272367

References

Region Start End Reference
five_prime_UTR32701913270234PMID:21511999
three_prime_UTR32720983272367PMID:21511999
three_prime_UTR32720983272367PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00533 IPR001357 Pfam BRCT domain 171 242 8
SM00060 IPR003961 SMART Fibronectin, type III 79 157 1
SM00292 IPR001357 SMART BRCT domain 169 246 12
PS50853 IPR003961 Prosite Profiles Fibronectin, type III 80 166 1
PS50172 IPR001357 Prosite Profiles BRCT domain 172 256 13
G3DSA:3.40.50.10190 Gene3D 172 258 12
G3DSA:2.60.40.10 IPR013783 Gene3D 81 167 2
SSF49265 IPR003961 SuperFamily 73 168 1
SSF52113 IPR001357 SuperFamily 171 256 12
Coil ncoils Rabaptin coiled-coil domain 434 458 974
PTHR13561 hmmpanther 1 620 2
PTHR13561:SF1 hmmpanther 1 620 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000443BRCT domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000443

Protein Properties

Ave. residue weight 108.44 Da
Charge -64.00
Isoelectric point 4.00
Molecular weight 67.23 kDa
Number of residues 620
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide14046.74PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide14814.87PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide0.91PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide4.6PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi only
conserved in fungi
conserved in eukaryotes
Manually curated orthologous groups
SpeciesGeneDescription

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
fus1formin Fus1 Phenotypic EnhancementPMID:16598689
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
rxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
whi5cell cycle transcriptional repressor Whi5 (predicted) Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC6G9.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC6G9.12 Retrieval of eukaryotic orthologs
BioGrid SPAC6G9.12 BioGRID Interaction Datasets
Bähler Lab SPAC6G9.12 Cell Cycle Expression Profile
Bähler Lab SPAC6G9.12 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC6G9.12 Pheromone response/mating expression profiles
Bähler Lab SPAC6G9.12 Environmental stress expression profiles
Bähler Lab SPAC6G9.12 Bähler Lab Transcriptome Viewer
Cyclebase SPAC6G9.12 Cell Cycle Data
PInt SPAC6G9.12 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC6G9.12 Entrez Gene
WikiGene2541978Chs five related protein Cfr1
Uniprot_genenameCFR1
EntrezGene2541978Chs five related protein Cfr1
SPD / RIKEN26/26C05Orfeome Localization Data
UniProtKB/SwissProtQ92357Cell fusion protein cfr1
ModBaseQ92357Database of comparative protein structure models
Pfam Protein DomainsQ92357Pfam Domain Arrangement
RefSeq PeptideNP_594121Chs five related protein Cfr1
RefSeq mRNANM_001019545972h- Chs five related protein Cfr1 (cfr1), mRNA
European Nucleotide ArchiveCAB03614ENA Protein Mapping
UniParcUPI0000127924UniProt Archive

Literature for cfr1

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013