tim14 (SPAC824.06)

Gene Standard Nametim14 ChromosomeI
Systematic IDSPAC824.06 Gene Start1694906
Synonyms Gene End1696484
ProductTIM23 translocase complex subunit Tim14 (predicted) Gene Length1579
Feature Typeprotein coding CDS Start1695102
Name Description CDS End1695624
Characterisation Statusbiological_role_inferred CDS Length523

Ensembl Gene Location
  1. bst1
  2. SPAC824.03c
  3. SPNCRNA.755
  4. SPAC824.04
  5. vps16
  6. tim14
  7. SPAC824.07
  8. gda1
  9. SPAC824.09c
  10. SPNCRNA.177
  11. swi6
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0001671ATPase activator activityISOSGD:S000003998GO_REF:0000024
GO:0015450P-P-bond-hydrolysis-driven protein transmembrane transporter activity
contributes_toISSUniProtKB:Q07914GO_REF:0000001
GO:0030544Hsp70 protein bindingISMPFAM:PF00226GO_REF:0000001
GO:0051082unfolded protein bindingISOSGD:S000003998GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006457protein foldingNASGO_REF:0000051
GO:0030150protein import into mitochondrial matrixISOSGD:S000003998GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0001405presequence translocase-associated import motorISOSGD:S000003998GO_REF:0000024
GO:0005739mitochondrionIDAPMID:16823372
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
116949061695104
216951521695199
316952531696484

References

Region Start End Reference
three_prime_UTR16956251696484PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00226 IPR001623 Pfam DnaJ domain 54 108 24
SM00271 IPR001623 SMART DnaJ domain 50 105 25
PS50076 IPR001623 Prosite Profiles DnaJ domain 51 113 24
G3DSA:1.10.287.110 IPR001623 Gene3D 41 103 26
SSF46565 IPR001623 SuperFamily 41 103 25
PTHR12763:SF5 hmmpanther 1 139 1
PTHR12763 hmmpanther 1 139 1
SignalP-noTM signalp 1 17 212

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.08 Da
Charge 15.00
Isoelectric point 11.25
Molecular weight 15.27 kDa
Number of residues 140
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1804.64PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide3827.42PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.5PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide1.9PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPAC824.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC824.06 Retrieval of eukaryotic orthologs
BioGrid SPAC824.06 BioGRID Interaction Datasets
Bähler Lab SPAC824.06 Cell Cycle Expression Profile
Bähler Lab SPAC824.06 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC824.06 Pheromone response/mating expression profiles
Bähler Lab SPAC824.06 Environmental stress expression profiles
Bähler Lab SPAC824.06 Bähler Lab Transcriptome Viewer
Cyclebase SPAC824.06 Cell Cycle Data
PInt SPAC824.06 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC824.06 Entrez Gene
WikiGene2542780TIM23 translocase complex subunit Tim14
Uniprot_genenamePAM18
EntrezGene2542780TIM23 translocase complex subunit Tim14
SPD / RIKEN05/05C01Orfeome Localization Data
UniProtKB/SwissProtQ9UT37Mitochondrial import inner membrane translocase subunit tim14
ModBaseQ9UT37Database of comparative protein structure models
Pfam Protein DomainsQ9UT37Pfam Domain Arrangement
RefSeq PeptideNP_593445TIM23 translocase complex subunit Tim14
RefSeq mRNANM_001018878972h- TIM23 translocase complex subunit Tim14 (tim14), mRNA
European Nucleotide ArchiveCAB57336ENA Protein Mapping
SPD / RIKEN05/05C01Orfeome Localization Data

Literature for tim14
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013