pcm2 (SPAC869.08)

Gene Standard Namepcm2 ChromosomeI
Systematic IDSPAC869.08 Gene Start5499280
Synonyms Gene End5497918
Productprotein-L-isoaspartate O-methyltransferase Pcm2 (predicted) Gene Length1363
Feature Typeprotein coding CDS Start5498965
Name DescriptionProtein Carboxyl Methyltransferase CDS End5498273
Characterisation Statusconserved_unknown CDS Length693

Ensembl Gene Location
  1. cat1
  2. SPNCRNA.1091
  3. put4
  4. SPNCRNA.1092
  5. SPAC869.09
  6. SPNCRNA.1093
  7. pcm2
  8. mel1
  9. SPAC869.06c
  10. SPNCRNA.279
  11. SPAC869.05c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopypcm2delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004719protein-L-isoaspartate (D-aspartate) O-methyltransferase activityISSUniProtKB:Q43209GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005737cytoplasmIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
154992805497918

References

Region Start End Reference
three_prime_UTR54982725497918PMID:21511999
five_prime_UTR54992805498966PMID:21511999
three_prime_UTR54982725497918PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01135 IPR000682 Pfam Protein-L-isoaspartate(D-aspartate) O-methyltransferase 9 223 1
G3DSA:3.40.50.150 Gene3D 8 225 65
SSF53335 SuperFamily 9 203 68
PTHR11579 IPR000682 hmmpanther Protein-L-isoaspartate(D-aspartate) O-methyltransferase 1 230 1
PTHR11579:SF0 hmmpanther 1 230 1
TIGR00080 IPR000682 tigrfam Protein-L-isoaspartate(D-aspartate) O-methyltransferase 9 223 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.14 Da
Charge 0.00
Isoelectric point 6.51
Molecular weight 25.33 kDa
Number of residues 230
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide0.18PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.53PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ppk14serine/threonine protein kinase Ppk14 (predicted) Negative GeneticPMID:22681890
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
rpl160160S ribosomal protein L13/L16 (predicted) Positive GeneticPMID:22681890
hus1checkpoint clamp complex protein Hus1 Positive GeneticPMID:22681890
dsk1SR protein-specific kinase Dsk1 Positive GeneticPMID:22681890
ers1RNA-silencing factor Ers1 Negative GeneticPMID:22681890
atb2tubulin alpha 2 Positive GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
vps35retromer complex subunit Vps35 Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPAC869.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC869.08 Retrieval of eukaryotic orthologs
BioGrid SPAC869.08 BioGRID Interaction Datasets
Bähler Lab SPAC869.08 Cell Cycle Expression Profile
Bähler Lab SPAC869.08 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC869.08 Pheromone response/mating expression profiles
Bähler Lab SPAC869.08 Environmental stress expression profiles
Bähler Lab SPAC869.08 Bähler Lab Transcriptome Viewer
Cyclebase SPAC869.08 Cell Cycle Data
PInt SPAC869.08 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC869.08 Entrez Gene
WikiGene2543383protein-L-isoaspartate O-methyltransferase Pcm2 (predicted)
Uniprot_genenamePCM2
EntrezGene2543383protein-L-isoaspartate O-methyltransferase Pcm2 (predicted)
IntEnz2.1.1.77
UniProtKB/SwissProtQ9URZ1Probable protein-L-isoaspartate O-methyltransferase
ModBaseQ9URZ1Database of comparative protein structure models
Pfam Protein DomainsQ9URZ1Pfam Domain Arrangement
RefSeq PeptideNP_595011protein-L-isoaspartate O-methyltransferase Pcm2 (predicted)
RefSeq mRNANM_001020442972h- protein-L-isoaspartate O-methyltransferase Pcm2 (predicted) (pcm2), mRNA
European Nucleotide ArchiveCAB60018ENA Protein Mapping
SPD / RIKEN08/08A11Orfeome Localization Data
UniParcUPI000006B5A9UniProt Archive

Literature for pcm2
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013