nup155 (SPAC890.06)


Gene Standard Namenup155 Characterisation Statuspublished
Systematic IDSPAC890.06 Feature Typeprotein coding
Synonymsnup157, nup170 Name Description
Productnucleoporin Nup155 Product Size1315aa, 147.63 kDa
Genomic Location Chromosome I, 5011683-5016066 (4384nt); CDS:5011732-5015786 (4055nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0017056structural constituent of nuclear poreIEAIPR004870GO_REF:00000023
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006407rRNA export from nucleusISOSGD:S000000907GO_REF:00000249
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005737cytoplasmIDAPMID:168233724201
GO:0005635nuclear envelopeIDAPMID:16823372137
GO:0005643nuclear poreISOSGD:S000000907GO_REF:000002454
during meiotic cell cycleIDAPMID:20970342
during mitotic cell cycleIDAPMID:20970342
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopynup155ΔNullPMID:204732893730
Microscopynup155ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopynup155ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
150116835011864
250119165012020
350120775016066

UTRs

Region Coordinates Reference
five_prime_UTR5011683..5011731PMID:21511999
three_prime_UTR5015787..5016066PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03177 Pfam IPR007187 Nucleoporin, Nup133/Nup155-like, C-terminal 668 1189 2
PF08801 Pfam IPR014908 Nucleoporin, Nup133/Nup155-like, N-terminal 66 511 3
PTHR10350 HMMPANTHER IPR004870 Nucleoporin, Nup155-like 1 1315 1
2.130.10.10 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 164 276 145
2.130.10.10 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 309 352 145
2.130.10.10 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 100 127 145
SSF101898 SuperFamily 101 272 2
SSF101898 SuperFamily 305 352 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.27 Da
Charge -17.50
Isoelectric point 5.30
Molecular weight 147.63 kDa
Number of residues 1315
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
21586during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
25338during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
22972during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
23257during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
23559during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
9673.22during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
5089.84during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
3.8during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.76during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Disease Association
DescriptionQualifierReferenceCount
heart disease1
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPAC890.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC890.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC890.06 BioGRID Interaction Datasets
Expression Viewer SPAC890.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC890.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC890.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC890.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC890.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC890.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC890.06 Cell Cycle Data
GEO SPAC890.06 GEO profiles
PInt SPAC890.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC890.06 Peptides identified in tandem mass spectrometry proteomics experiments
WikiGene2543502nucleoporin Nup157/170
EntrezGene2543502nucleoporin Nup157/170
SPD / RIKEN30/30F01Orfeome Localization Data
UniProtKB/SwissProtQ9URX8Probable nucleoporin C890.06
ModBaseQ9URX8Database of comparative protein structure models
STRINGQ9URX8Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594824nucleoporin Nup157/170
RefSeq mRNANM_001020253972h- nucleoporin Nup157/170 (SPAC890.06), mRNA
European Nucleotide ArchiveBAA87192ENA Protein Mapping
European Nucleotide ArchiveBAA87192.1ENA Protein Mapping
European Nucleotide ArchiveCAB63497ENA Protein Mapping
European Nucleotide ArchiveCAB63497.1ENA Protein Mapping
UniParcUPI000006C80FUniProt Archive

Literature for nup155

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014