nup155 (SPAC890.06)


Gene Standard Namenup155 Characterisation Statuspublished
Systematic IDSPAC890.06 Feature Typeprotein coding
Synonymsnup157, nup170 Name Description
Productnucleoporin Nup155 Product Size1315aa, 147.63 kDa
Genomic Location Chromosome I, 5011683-5016066 (4384nt); CDS:5011732-5015786 (4055nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of nuclear pore3
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
nucleocytoplasmic transport110
Annotation ExtensionEvidenceWith/FromReference
rRNA export from nucleus8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
inviable cell populationnup155Δ1467
viable vegetative cell populationnup155Δ3837

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologynup155Δ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons5011683..5011864, 5011916..5012020, 5012077..5016066
Intron5011865..5011915, 5012021..5012076
5' UTR5011683..5011731PMID:21511999
3' UTR5015787..5016066PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03177 Pfam IPR007187 Nucleoporin, Nup133/Nup155-like, C-terminal 755 1188 3
PF08801 Pfam IPR014908 Nucleoporin, Nup133/Nup155-like, N-terminal 60 511 3
PTHR10350 HMMPANTHER IPR004870 Nucleoporin, Nup155-like 396 1315 1
PTHR10350 HMMPANTHER IPR004870 Nucleoporin, Nup155-like 1 380 1
PTHR10350:SF6 HMMPANTHER 396 1315 1
PTHR10350:SF6 HMMPANTHER 1 380 1
2.130.10.10 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 100 127 145
2.130.10.10 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 164 276 145
2.130.10.10 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 309 352 145
SSF101898 SuperFamily 101 272 2
SSF101898 SuperFamily 305 352 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.27 Da
Charge -17.50
Codon Adaptation Index 0.44
Isoelectric point 5.30
Molecular weight 147.63 kDa
Number of residues 1315
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for nup155 (SPAC890.06)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
21586during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
25338during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
22972during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
23257during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
9673.22during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
23559during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
5089.84during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.8during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.76during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Disease Association
DescriptionQualifierReferenceCount
heart disease3
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4605
conserved in eukaryotes4515
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2505
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC890.06 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds DNA-binding domain construct withman1LEM domain protein Man1, Sad1 interacting factor Two-hybridPMID:26771498
binds DNA-binding domain construct withtvp15COPI-coated vesicle associated protein (predicted) Two-hybridPMID:26771498
binds activation domain construct withrtn1reticulon-like protein Rtn1 Two-hybridPMID:26771498
binds activation domain construct withmge1mitochondrial GrpE domain chaperone protein (predicted) Two-hybridPMID:26771498
binds activation domain construct withsad1spindle pole body protein Sad1 Two-hybridPMID:26771498
binds activation domain construct withyop1ER membrane protein DP1/Yop1 Two-hybridPMID:26771498
binds activation domain construct withima1inner nuclear membrane protein Ima1 Two-hybridPMID:26771498
External References
Database Identifier Description
NBRP SPAC890.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC890.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC890.06 BioGRID Interaction Datasets
Expression Viewer SPAC890.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC890.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC890.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC890.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC890.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC890.06 Transcriptome Viewer (Bähler Lab)
GEO SPAC890.06 GEO profiles
PInt SPAC890.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC890.06 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC890.06 Fission yeast phenotypic data & analysis
Cyclebase SPAC890.06.1 Cell Cycle Data
SPD / RIKEN30/30F01Orfeome Localization Data
UniProtKB/SwissProtQ9URX8Probable nucleoporin C890.06
ModBaseQ9URX8Database of comparative protein structure models
STRINGQ9URX8Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594824nucleoporin Nup155
RefSeq mRNANM_001020253972h- nucleoporin Nup155 (nup155), mRNA

Literature for nup155

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016