SPAC8F11.04


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC8F11.04 Feature Typeprotein coding
Synonyms Name Description
ProductU3 snoRNP-associated protein Cic1/Utp30 family (predicted) Product Size373aa, 41.36 kDa
Genomic Location Chromosome I, 2859388-2861935 (2548nt); CDS:2859456-2860704 (1249nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030490maturation of SSU-rRNAISOSGD:S000001768GO_REF:000002438
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005730nucleolusIDAPMID:16823372357
ISOSGD:S000001768GO_REF:0000024
GO:0005634nucleusISOSGD:S000001768GO_REF:00000242737
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopySPAC8F11.04ΔNullPMID:204732891337
MicroscopySPAC8F11.04ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001042inviable after spore germination, single or double cell division96
penetrance FYPO_EXT:0000003MicroscopySPAC8F11.04ΔNullPECO:0000005, PECO:0000137PMID:23697806
FYPO:0000313inviable after spore germination, without cell division, with abnormal germ tube morphology146
penetrance FYPO_EXT:0000001MicroscopySPAC8F11.04ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
128593882859491
228596192860878
328609202861935
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1/ribosomal biogenesis protein 19 248 5
PTHR23105 HMMPANTHER 14 284 9
PTHR23105:SF3 HMMPANTHER 14 284 1
3.40.50.790 Gene3D IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich 110 167 4
3.30.190.20 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 168 251 5
SSF56808 SuperFamily IPR023674 Ribosomal protein L1-like 41 252 5

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.88 Da
Charge 30.00
Isoelectric point 10.46
Molecular weight 41.36 kDa
Number of residues 373
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS279PMID:247631071670
present during cellular response to thiabendazoleIDAS279PMID:18257517
MOD:00696phosphorylated residueNASPMID:182575171922
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA leveldecreased during GO:0071470expression microarray evidencePMID:12529438
decreased during GO:0034605expression microarray evidencePMID:12529438
decreased in presence of cadmium sulfate expression microarray evidencePMID:12529438
decreased during GO:0034599expression microarray evidencePMID:12529438
decreased in presence of methyl methanesulfonate expression microarray evidencePMID:12529438

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
20104during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
21510during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
19546during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
18741during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
9696.87during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
21310during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
5186.73during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5.1during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4599
conserved in eukaryotes4514
conserved in metazoa3428
conserved in vertebrates3402
conserved in eukaryotes only2498
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
clp1Cdc14-related protein phosphatase Clp1/Flp1 Affinity Capture-MSPMID:23297348
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:21436456
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
mlo3RNA binding protein Mlo3 Affinity Capture-MSPMID:21436456
External References
Database Identifier Description
NBRP SPAC8F11.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC8F11.04 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC8F11.04 BioGRID Interaction Datasets
Expression Viewer SPAC8F11.04 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC8F11.04 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC8F11.04 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC8F11.04 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC8F11.04 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC8F11.04 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC8F11.04 Cell Cycle Data
GEO SPAC8F11.04 GEO profiles
PInt SPAC8F11.04 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC8F11.04 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN19/19H12Orfeome Localization Data
UniProtKB/SwissProtQ9UT32Putative ribosome biogenesis protein C8F11.04
ModBaseQ9UT32Database of comparative protein structure models
STRINGQ9UT32Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593953U3 snoRNP-associated protein Cic1/Utp30 family (predicted)
European Nucleotide ArchiveCAB52165.1ENA Protein Mapping
UniParcUPI000006973DUniProt Archive

Literature for SPAC8F11.04

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014