SPAC8F11.04


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC8F11.04 Feature Typeprotein coding
Synonyms Name Description
ProductU3 snoRNP-associated protein Cic1/Utp30 family (predicted) Product Size373aa, 41.36 kDa
Genomic Location Chromosome I, 2859388-2861935 (2548nt); CDS:2859456-2860704 (1249nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030490maturation of SSU-rRNAISOSGD:S000001768GO_REF:000002437
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005730nucleolusIDAPMID:16823372345
ISOSGD:S000001768GO_REF:0000024
GO:0005634nucleusISOSGD:S000001768GO_REF:00000242730
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopySPAC8F11.04ΔNullPECO:0000005, PECO:0000137PMID:236978061309
MicroscopySPAC8F11.04ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001042inviable after spore germination, single or double cell divisionMicroscopySPAC8F11.04ΔNullPECO:0000005, PECO:0000137PMID:2369780691
penetrance FYPO_EXT:0000003
FYPO:0000313inviable after spore germination, without cell division, with abnormal germ tube morphologyMicroscopySPAC8F11.04ΔNullPECO:0000005, PECO:0000137PMID:23697806144
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
128593882859491
228596192860878
328609202861935

UTRs

Region Start End Reference
three_prime_UTR28609202861935PMID:21511999
three_prime_UTR28607052860878PMID:21511999
five_prime_UTR28593882859455PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1 19 248 5
PTHR23105 HMMPANTHER 14 284 9
PTHR23105:SF3 HMMPANTHER 14 284 1
G3DSA:3.40.50.790 Gene3D IPR016095 110 177 4
SSF56808 SuperFamily IPR023674 41 252 5
Low complexity (SEG) seg 161 172
Low complexity (SEG) seg 286 300
Low complexity (SEG) seg 362 372

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.88 Da
Charge 30.00
Isoelectric point 10.46
Molecular weight 41.36 kDa
Number of residues 373
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residuePMID:182575171192
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA leveldecreasedexpression microarray evidencePMID:12529438
during GO:0071470
decreased,
in presence of methyl methanesulfonate
expression microarray evidencePMID:12529438
decreasedexpression microarray evidencePMID:12529438
during GO:0034599
decreased,
in presence of cadmium sulfate
expression microarray evidencePMID:12529438
decreasedexpression microarray evidencePMID:12529438
during GO:0034605

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
5186.73during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
9696.87during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
5.1during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
clp1Cdc14-related protein phosphatase Clp1/Flp1 Affinity Capture-MSPMID:23297348
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:21436456
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
mlo3RNA binding protein Mlo3 Affinity Capture-MSPMID:21436456
External References
Database Identifier Description
NBRP SPAC8F11.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC8F11.04 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC8F11.04 BioGRID Interaction Datasets
Expression Viewer SPAC8F11.04 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC8F11.04 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC8F11.04 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC8F11.04 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC8F11.04 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC8F11.04 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC8F11.04 Cell Cycle Data
GEO SPAC8F11.04 GEO profiles
PInt SPAC8F11.04 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2543438U3 snoRNP-associated protein Cic1/Utp30 family (predicted)
EntrezGene2543438U3 snoRNP-associated protein Cic1/Utp30 family (predicted)
SPD / RIKEN19/19H12Orfeome Localization Data
UniProtKB/SwissProtQ9UT32Putative ribosome biogenesis protein C8F11.04
ModBaseQ9UT32Database of comparative protein structure models
StringQ9UT32Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593953U3 snoRNP-associated protein Cic1/Utp30 family (predicted)
RefSeq mRNANM_001019380972h- U3 snoRNP-associated protein Cic1/Utp30 family (predicted) (SPAC8F11.04), mRNA
European Nucleotide ArchiveCAB52165ENA Protein Mapping
UniParcUPI000006973DUniProt Archive

Literature for SPAC8F11.04

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014