Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPAC8F11.04 Feature Typeprotein coding
Synonyms Name Description
ProductU3 snoRNP-associated protein Cic1/Utp30 family (predicted) Product Size373aa, 41.36 kDa
Genomic Location Chromosome I, 2859388-2861935 (2548nt); CDS:2859456-2860704 (1249nt)

Ensembl Gene Location
GO Biological Process

GO Slim Terms

ribosome biogenesis

Term NameCount
maturation of SSU-rRNA51
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationSPAC8F11.04Δ1468

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, single or double cell divisionSPAC8F11.04Δ107
inviable after spore germination, without cell division, with abnormal germ tube morphologySPAC8F11.04Δ153
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2859388..2859491, 2859619..2860878, 2860920..2861935
Intron2859492..2859618, 2860879..2860919
5' UTR2859388..2859455PMID:21511999
CDS2859456..2859491, 2859619..2860704
3' UTR2860705..2860878, 2860920..2861935PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1/ribosomal biogenesis protein 28 247 5
PTHR23105 HMMPANTHER 51 272 8
PTHR23105:SF31 HMMPANTHER 51 272 2 Gene3D IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich 110 167 4 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 168 251 5
SSF56808 SuperFamily IPR023674 Ribosomal protein L1-like 41 252 5

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.88 Da
Charge 30.00
Codon Adaptation Index 0.44
Isoelectric point 10.46
Molecular weight 41.36 kDa
Number of residues 373

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 2293
present during cellular response to thiabendazoleS279
S162, S279
Annotation ExtensionEvidenceResidueReference
present during cellular response to thiabendazole IDA S279 PMID:18257517
experimental evidence S279 PMID:24763107
IDA S162 PMID:25720772
Gene Expression

Qualitative Gene Expression

RNA leveldecreased in presence of methyl methanesulfonate expression microarray evidencePMID:12529438
decreased in presence of cadmium sulfate expression microarray evidencePMID:12529438
decreased during GO:0034605expression microarray evidencePMID:12529438
decreased during GO:0071470expression microarray evidencePMID:12529438
decreased during GO:0034599expression microarray evidencePMID:12529438

Quantitative Gene Expression

View graphical display of gene expression data for SPAC8F11.04

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
20104during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
21510during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
19546during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
18741during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
9696.87during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
21310during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
5186.73during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5.1during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473
conserved in eukaryotes only2525

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC8F11.04 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bycid14TRAMP complex poly(A) polymerase subunit Cid14 Affinity Capture-MSPMID:21436456
affinity captured byred5human ZC3H3 homolog Affinity Capture-MSPMID:24713849
affinity captured byclp1Cdc14-related protein phosphatase Clp1/Flp1 Affinity Capture-MSPMID:23297348
affinity captured bymlo3RNA binding protein Mlo3 Affinity Capture-MSPMID:21436456
affinity captured bymtl1TRAMP/MTREC complex subunit, ATP-dependent RNA helicase (predicted) Affinity Capture-MSPMID:24713849
affinity captured bypir2zf-C2H2 type zinc finger protein, implicated in RNAi (predicted) Affinity Capture-MSPMID:24713849
affinity captured byred1RNA elimination defective protein Red1 Affinity Capture-MSPMID:24713849
External References
Database Identifier Description
NBRP SPAC8F11.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC8F11.04 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC8F11.04 BioGRID Interaction Datasets
Expression Viewer SPAC8F11.04 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC8F11.04 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC8F11.04 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC8F11.04 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC8F11.04 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC8F11.04 Transcriptome Viewer (Bähler Lab)
GEO SPAC8F11.04 GEO profiles
PInt SPAC8F11.04 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC8F11.04 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC8F11.04 Fission yeast phenotypic data & analysis
Cyclebase SPAC8F11.04.1 Cell Cycle Data
SPD / RIKEN19/19H12Orfeome Localization Data
UniProtKB/SwissProtQ9UT32Putative ribosome biogenesis protein C8F11.04
ModBaseQ9UT32Database of comparative protein structure models
STRINGQ9UT32Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593953U3 snoRNP-associated protein Cic1/Utp30 family (predicted)
European Nucleotide ArchiveCAB52165.1ENA Protein Mapping
UniParcUPI000006973DUniProt Archive

Literature for SPAC8F11.04

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017