rpl3001 (SPAC9G1.03c)

Gene Standard Namerpl3001 Characterisation Statusbiological_role_inferred
Systematic IDSPAC9G1.03c Feature Typeprotein coding
Synonymsrpl30, rpl30-1 Name Description
Product60S ribosomal protein L30 (predicted) Product Size109aa, 11.59 kDa
Genomic Location Chromosome I, 1974092-1973479 (614nt); CDS:1974054-1973666 (389nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation470
Annotation ExtensionEvidenceWith/FromReference
rRNA processing194
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to tacrolimus81
expressivity FYPO_EXT:0000003rpl3001ΔNull
viable vegetative cell populationrpl3001ΔNull3781

Cell Phenotype

Term NameAlleleExpressionCount
abnormal actin cytoskeletonrpl3001ΔNull43
abnormal microtubule cytoskeletonrpl3001ΔNull225
abnormal microtubule cytoskeleton morphology during mitotic interphase186
penetrance FYPO_EXT:0000002rpl3001ΔNull
abolished activation of bipolar cell growthrpl3001ΔNull13
decreased pre-mRNA level1
affecting rpl3002rpl3001::kanMX6 (disruption)Not specified
elongated telomeres160
expressivity FYPO_EXT:0000003rpl3001ΔNull
single microtubule bundlerpl3001ΔNull10
viable vegetative cell, abnormal cell shape, normal cell size215
penetrance FYPO_EXT:0000001, expressivity FYPO_EXT:0000003rpl3001ΔNull
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01248 Pfam IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 15 107 7
PS00993 Prosite Patterns IPR022991 Ribosomal protein L30e, conserved site 82 102 2
PS00709 Prosite Patterns IPR022991 Ribosomal protein L30e, conserved site 26 50 2
PTHR11449:SF1 HMMPANTHER 3 109 2
PTHR11449 HMMPANTHER IPR000231 Ribosomal protein L30e 3 109 2
3.30.1330.30 Gene3D IPR029064 50S ribosomal protein L30e-like 8 107 10
SSF55315 SuperFamily IPR029064 50S ribosomal protein L30e-like 15 107 10

View domain organization at Pfam

Protein Properties

Ave. residue weight 106.35 Da
Charge 10.00
Isoelectric point 10.25
Molecular weight 11.59 kDa
Number of residues 109

Protein Modifications

Term NameResidueCount
phosphorylated residue 1922
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
276697during GO:0000080PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
251282during GO:0000084PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
228835during GO:0000085PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
266670during GO:0000087PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
258070during GO:0072690PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
138909.29during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
48435.93during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
62during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
5.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4604
conserved in eukaryotes4516
conserved in bacteria1000
conserved in metazoa3432
conserved in vertebrates3407

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
fic1C2 domain protein Fic1 Affinity Capture-MSPMID:19139265
sog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
pab2poly(A) binding protein Pab2 Affinity Capture-MSPMID:19336419
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
pmc1mediator complex subunit Pmc1 Negative GeneticPMID:22681890
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
cwf18complexed with Cdc5 protein Cwf18 Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
cwf28splicing factor Cwf28 Negative GeneticPMID:22681890
cdr2serine/threonine protein kinase Cdr2 Negative GeneticPMID:22681890
srp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
SPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
aar2U5 snRNP-associated protein Aar2 (predicted) Positive GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
spc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
gcn20AAA family ATPase Gcn20 (predicted) Negative GeneticPMID:22681890
not2CCR4-Not complex subunit Not2 (predicted) Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
int6eIF3e subunit Int6 Negative GeneticPMID:22681890
swr1SNF2 family ATP-dependent DNA helicase Swr1 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
sif1Sad1 interacting factor 1 Positive GeneticPMID:22681890
pfd1prefoldin subunit 1 (predicted) Negative GeneticPMID:22681890
prp19ubiquitin-protein ligase E4 Negative GeneticPMID:22681890
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
SPAC1952.06cspliceosomal complex subunit (predicted) Negative GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC9G1.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC9G1.03c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC9G1.03c BioGRID Interaction Datasets
Expression Viewer SPAC9G1.03c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC9G1.03c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC9G1.03c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC9G1.03c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC9G1.03c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC9G1.03c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC9G1.03c Cell Cycle Data
GEO SPAC9G1.03c GEO profiles
PInt SPAC9G1.03c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC9G1.03c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC9G1.03c Fission yeast phenotypic data & analysis
SPD / RIKEN02/02H06Orfeome Localization Data
UniProtKB/SwissProtP5280860S ribosomal protein L30-1
ModBaseP52808Database of comparative protein structure models
STRINGP52808Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59355860S ribosomal protein L30
RefSeq mRNANM_001018991972h- 60S ribosomal protein L30 (rpl3001), mRNA
European Nucleotide ArchiveU97398ENA EMBL mapping
European Nucleotide ArchiveAAB17132.1ENA Protein Mapping
European Nucleotide ArchiveCAB11499.1ENA Protein Mapping
UniParcUPI0000132F9BUniProt Archive

Literature for rpl3001

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015