SPAC9G1.05

Gene Standard NameUnassigned ChromosomeI
Systematic IDSPAC9G1.05 Gene Start1976706
Synonyms Gene End1979209
Productactin cortical patch component Aip1 (predicted) Gene Length2504
Feature Typeprotein coding CDS Start1976902
Name Description CDS End1979061
Characterisation Statusbiological_role_inferred CDS Length2160

Ensembl Gene Location
  1. wis4
  2. rpl3001
  3. oxa101
  4. SPAC9G1.05
  5. cyk3
  6. SPAC9G1.07
  7. SPAC9G1.08c
  8. mzt1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000088sensitive to hydroxyureacompetitive growth assay evidenceSPAC9G1.05delta (deletion)deletionPMID:20537132
FYPO:0000266sensitive to DNA damaging agentscompetitive growth assay evidenceSPAC9G1.05delta (deletion)deletionPMID:20537132
FYPO:0001491viable vegetative cellMicroscopySPAC9G1.05delta (deletion)deletionPMID:20473289
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0030042actin filament depolymerizationISOSGD:S000004698GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusISOSGD:S000004698GO_REF:0000024
IDAPMID:16823372
GO:0005737cytoplasmISOSGD:S000004698GO_REF:0000024
GO:0005829cytosolIDAPMID:16823372
GO:0030479actin cortical patchISOSGD:S000004698GO_REF:0000024
GO:0032153cell division siteIDAPMID:16823372
GO:0043234protein complexNASGO_REF:0000051
GO:0051286cell tipIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
119767061977006
219770681977191
319772621977363
419774041977449
519775561977601
619776511978592
719786391979209

References

Region Start End Reference
three_prime_UTR19790621979209PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00400 IPR001680 Pfam WD40 repeat 222 259 104
PF00400 IPR001680 Pfam WD40 repeat 54 86 104
PF00400 IPR001680 Pfam WD40 repeat 521 550 104
PF00400 IPR001680 Pfam WD40 repeat 474 507 104
PF00400 IPR001680 Pfam WD40 repeat 306 343 104
PF00400 IPR001680 Pfam WD40 repeat 183 217 104
SM00320 IPR001680 SMART WD40 repeat 135 175 120
SM00320 IPR001680 SMART WD40 repeat 347 384 120
SM00320 IPR001680 SMART WD40 repeat 468 507 120
SM00320 IPR001680 SMART WD40 repeat 304 343 120
SM00320 IPR001680 SMART WD40 repeat 511 550 120
SM00320 IPR001680 SMART WD40 repeat 220 259 120
SM00320 IPR001680 SMART WD40 repeat 178 217 120
SM00320 IPR001680 SMART WD40 repeat 47 86 120
SM00320 IPR001680 SMART WD40 repeat 554 592 120
SM00320 IPR001680 SMART WD40 repeat 419 463 120
PS50082 IPR001680 Prosite Profiles WD40 repeat 185 226 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 54 86 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 561 595 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 227 268 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 475 516 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 311 344 100
PS50294 IPR017986 Prosite Profiles WD40-repeat-containing domain 54 595 104
G3DSA:2.130.10.10 IPR015943 Gene3D 54 388 144
G3DSA:2.130.10.10 IPR015943 Gene3D 419 593 144
SSF50978 IPR017986 SuperFamily 283 389 135
SSF50978 IPR017986 SuperFamily 26 343 135
SSF50978 IPR017986 SuperFamily 422 593 135
PTHR19856 hmmpanther 1 595 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190

Protein Properties

Ave. residue weight 109.69 Da
Charge 0.00
Isoelectric point 6.50
Molecular weight 65.27 kDa
Number of residues 595
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide19028.57PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide17904.61PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide4.9PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
lub1WD repeat protein Lub1 Negative GeneticPMID:22681890
clp1Cdc14-related protein phosphatase Clp1/Flp1 Phenotypic EnhancementPMID:21931816
trt1telomerase reverse transcriptase 1 protein Trt1 Negative GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
prw1Clr6 histone deacetylase complex subunit Prw1 Positive GeneticPMID:22681890
sre2membrane-tethered transcription factor (predicted) Negative GeneticPMID:21504829
prp4serine/threonine protein kinase Prp4 Positive GeneticPMID:22681890
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Positive GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Negative GeneticPMID:22681890
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
adf1actin depolymerizing factor, cofilin Synthetic LethalityPMID:22024167
SPBC21C3.03ABC1 kinase family protein Negative GeneticPMID:22681890
pob3FACT complex subunit Pob3 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Negative GeneticPMID:22681890
vps5retromer complex subunit Vps5 Positive GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
res2MBF transcription factor complex subunit Res2 Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
SPAC29A4.02ctranslation elongation factor EF-1 gamma subunit Negative GeneticPMID:22681890
raf2Rik1-associated factor Raf2 Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
cid13poly(A) polymerase Cid13 Affinity Capture-MSPMID:12062100
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External References
Database Identifier Description
NBRP SPAC9G1.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC9G1.05 Retrieval of eukaryotic orthologs
BioGrid SPAC9G1.05 BioGRID Interaction Datasets
Bähler Lab SPAC9G1.05 Cell Cycle Expression Profile
Bähler Lab SPAC9G1.05 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC9G1.05 Pheromone response/mating expression profiles
Bähler Lab SPAC9G1.05 Environmental stress expression profiles
Bähler Lab SPAC9G1.05 Bähler Lab Transcriptome Viewer
Cyclebase SPAC9G1.05 Cell Cycle Data
PInt SPAC9G1.05 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC9G1.05 Entrez Gene
WikiGene2542795actin cortical patch component Aip1 (predicted)
EntrezGene2542795actin cortical patch component Aip1 (predicted)
SPD / RIKEN37/37F11Orfeome Localization Data
UniProtKB/SwissProtO14301Uncharacterized WD repeat-containing protein C9G1.05
ModBaseO14301Database of comparative protein structure models
Pfam Protein DomainsO14301Pfam Domain Arrangement
RefSeq PeptideNP_593560actin cortical patch component Aip1 (predicted)
RefSeq mRNANM_001018993972h- actin cortical patch component Aip1 (predicted) (SPAC9G1.05), mRNA
European Nucleotide ArchiveCAB11489ENA Protein Mapping
SPD / RIKEN37/37F11Orfeome Localization Data

Literature for SPAC9G1.05
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013