swc4 (SPAC9G1.13c)

Gene Standard Nameswc4 ChromosomeI
Systematic IDSPAC9G1.13c Gene Start1996858
Synonyms Gene End1995130
ProductSwr1 complex subunit Swc4 Gene Length1729
Feature Typeprotein coding CDS Start1996683
Name Description CDS End1995208
Characterisation Statuspublished CDS Length1476

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopyswc4delta (deletion)deletionPMID:20473289
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0003677DNA bindingISOSGD:S000003234GO_REF:0000024
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
GO:0006281DNA repairISOSGD:S000003234GO_REF:0000024
GO:0006338chromatin remodelingISOSGD:S000003234GO_REF:0000024
GO:0006355regulation of transcription, DNA-dependentIEAUniProtKB:KW-0805GO_REF:0000037
GO:0016573histone acetylationICGO:0035267GO_REF:0000001
GO:0043486histone exchangeIPIGO:0000812PMID:19040720
GO:0043967histone H4 acetylationIEAIPR027109GO_REF:0000002
GO:0043968histone H2A acetylationIEAIPR027109GO_REF:0000002
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0000790nuclear chromatinICGO_REF:0000001
GO:0000812Swr1 complexIDAPMID:19040720
GO:0005634nucleusIDAPMID:16823372
GO:0035267NuA4 histone acetyltransferase complexIDAPMID:19040720
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
119968581996478
219964131996325
319962681996191
419961481995130

References

Region Start End Reference
five_prime_UTR19968581996684PMID:21511999
five_prime_UTR19968581996684PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
SM00717 IPR001005 SMART SANT/Myb domain 124 178 15
Coil ncoils Rabaptin coiled-coil domain 391 412 974
PTHR12855:SF1 hmmpanther 2 436 1
PTHR12855 hmmpanther SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 2 436 1

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0001260Myb familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001260

Protein Properties

Ave. residue weight 115.30 Da
Charge 10.00
Isoelectric point 9.30
Molecular weight 50.38 kDa
Number of residues 437
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000005,
PECO:0000014
population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_widePMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005
population_wide2.2PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide0.48PMID:23101633
Misc
DescriptionQualifierReference
proteome hyperlink PMID:19040720
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
msc1multi-copy suppressor of Chk1 Affinity Capture-MSPMID:19910462
Affinity Capture-MSPMID:20858896
swr1SNF2 family helicase Swr1 Affinity Capture-MSPMID:19910462
tra2NuA4 complex phosphatidylinositol pseudokinase complex subunit Tra2 Affinity Capture-MSPMID:21642955
External References
Database Identifier Description
NBRP SPAC9G1.13c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC9G1.13c Retrieval of eukaryotic orthologs
BioGrid SPAC9G1.13c BioGRID Interaction Datasets
Bähler Lab SPAC9G1.13c Cell Cycle Expression Profile
Bähler Lab SPAC9G1.13c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC9G1.13c Pheromone response/mating expression profiles
Bähler Lab SPAC9G1.13c Environmental stress expression profiles
Bähler Lab SPAC9G1.13c Bähler Lab Transcriptome Viewer
Cyclebase SPAC9G1.13c Cell Cycle Data
PInt SPAC9G1.13c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC9G1.13c Entrez Gene
WikiGene2542412Swr1 complex subunit Swc4
Uniprot_genenameSWC4
EntrezGene2542412Swr1 complex subunit Swc4
UniProtKB/SwissProtO14308SWR1-complex protein 4
ModBaseO14308Database of comparative protein structure models
Pfam Protein DomainsO14308Pfam Domain Arrangement
RefSeq PeptideNP_593568Swr1 complex subunit Swc4
RefSeq mRNANM_001019001972h- Swr1 complex subunit Swc4 (swc4), mRNA
European Nucleotide ArchiveCAB11497ENA Protein Mapping
SPD / RIKEN44/44G09Orfeome Localization Data
UniParcUPI0001B062A9UniProt Archive

Literature for swc4

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013