mdb1 (SPACUNK4.14)

Gene Standard Namemdb1 ChromosomeI
Systematic IDSPACUNK4.14 Gene Start2885542
Synonyms Gene End2882793
ProductBRCT domain protein Gene Length2750
Feature Typeprotein coding CDS Start2885220
Name Description CDS End2883184
Characterisation Statusconserved_unknown CDS Length2037

Ensembl Gene Location
  1. mug153
  2. SPACUNK4.16c
  3. SPACUNK4.15
  4. mdb1
  5. SPACUNK4.13c
  6. prl56
  7. mug138
  8. mpp6
  9. SPACUNK4.10
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopymdb1delta (deletion)deletionPMID:20473289
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
128855422884987
228849322884840
328847832883542
428834892882793

References

Region Start End Reference
three_prime_UTR28831832882793PMID:21511999
three_prime_UTR28831832882793PMID:21511999
five_prime_UTR28855422885221PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00533 IPR001357 Pfam BRCT domain 400 455 8
SM00292 IPR001357 SMART BRCT domain 380 458 12
PS50172 IPR001357 Prosite Profiles BRCT domain 400 468 13
G3DSA:3.40.50.10190 Gene3D 359 466 12
SSF52113 IPR001357 SuperFamily 392 485 12

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000443BRCT domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000443

Protein Properties

Ave. residue weight 112.50 Da
Charge -23.00
Isoelectric point 4.71
Molecular weight 70.20 kDa
Number of residues 624
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide452.13PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide809.46PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.5PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.53PMID:23101633
Warning
DescriptionQualifierReference
gene structure updated PMID:21270388
Species Distribution
DescriptionQualifierReference
orthologs cannot be distinguished
conserved in eukaryotes
conserved in eukaryotes only
Contact Curators
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
ark1aurora-B kinase Ark1 Biochemical ActivityPMID:21712547
Contact Curators
External References
Database Identifier Description
NBRP SPACUNK4.14 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPACUNK4.14 Retrieval of eukaryotic orthologs
BioGrid SPACUNK4.14 BioGRID Interaction Datasets
Bähler Lab SPACUNK4.14 Cell Cycle Expression Profile
Bähler Lab SPACUNK4.14 Meiosis/Sporulation Expression Profies
Bähler Lab SPACUNK4.14 Pheromone response/mating expression profiles
Bähler Lab SPACUNK4.14 Environmental stress expression profiles
Bähler Lab SPACUNK4.14 Bähler Lab Transcriptome Viewer
Cyclebase SPACUNK4.14 Cell Cycle Data
PInt SPACUNK4.14 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPACUNK4.14 Entrez Gene
WikiGene2542517BRCT domain protein
Uniprot_genenameMDB1
EntrezGene2542517BRCT domain protein
SPD / RIKEN35/35A01Orfeome Localization Data
UniProtKB/SwissProtO14079Uncharacterized protein mdb1
ModBaseO14079Database of comparative protein structure models
Pfam Protein DomainsO14079Pfam Domain Arrangement
RefSeq PeptideNP_593964BRCT domain protein
RefSeq mRNANM_001019391972h- BRCT domain protein (mdb1), mRNA
European Nucleotide ArchiveCAA20144ENA Protein Mapping
UniParcUPI000228F483UniProt Archive

Literature for mdb1
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013