rpl1002 (SPAP7G5.05)


Gene Standard Namerpl1002 Characterisation Statuspublished
Systematic IDSPAP7G5.05 Feature Typeprotein coding
Synonymsrpl10, rpl10-2 Name Description
Product60S ribosomal protein L10 Product Size221aa, 25.36 kDa
Genomic Location Chromosome I, 3744043-3744906 (864nt); CDS:3744164-3744829 (666nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000004065GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0042254ribosome biogenesisISOSGD:S000004065GO_REF:0000024326
GO:0006412translationISOSGD:S000004065GO_REF:0000024597
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
GO:0022625cytosolic large ribosomal subunitISOSGD:S000004065GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrpl1002ΔNullPMID:204732893760
Microscopyrpl1002ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001Microscopyrpl1002ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
137440433744906

UTRs

Region Coordinates Reference
five_prime_UTR3744043..3744163PMID:21511999
three_prime_UTR3744830..3744906PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00252 Pfam IPR016180 Ribosomal protein L10e/L16 5 166 3
PS01257 Prosite Patterns IPR018255 Ribosomal protein L10e, conserved site 108 129 2
PTHR11726 HMMPANTHER 2 217 2
3.90.1170.10 Gene3D IPR016180 Ribosomal protein L10e/L16 4 173 3
SSF54686 SuperFamily IPR016180 Ribosomal protein L10e/L16 4 173 3
PIRSF005590 PIRSF IPR001197 Ribosomal protein L10e 1 188 2
TIGR00279 tigrfam IPR001197 Ribosomal protein L10e 1 172 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.75 Da
Charge 25.50
Isoelectric point 10.61
Molecular weight 25.36 kDa
Number of residues 221
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
86913.59during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
4545.43during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
50during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
4.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in bacteria1001
conserved in metazoa3419
conserved in vertebrates3393
conserved in archaea237
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
sre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
srp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
ppk14serine/threonine protein kinase Ppk14 (predicted) Negative GeneticPMID:22681890
apc10anaphase-promoting complex subunit Apc10 Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
dad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
SPBC19G7.04HMG box protein Negative GeneticPMID:22681890
ago1argonaute Positive GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
hri1eIF2 alpha kinase Hri1 Negative GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
fan1Fanconi-associated nuclease Fan1 Synthetic LethalityPMID:24192486
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
mug154conserved fungal protein Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
External References
Database Identifier Description
NBRP SPAP7G5.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAP7G5.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAP7G5.05 BioGRID Interaction Datasets
Expression Viewer SPAP7G5.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAP7G5.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAP7G5.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAP7G5.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAP7G5.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAP7G5.05 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAP7G5.05 Cell Cycle Data
GEO SPAP7G5.05 GEO profiles
PInt SPAP7G5.05 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene254167860S ribosomal protein L10
EntrezGene254167860S ribosomal protein L10
UniProtKB/SwissProtQ9P76960S ribosomal protein L10-B
ModBaseQ9P769Database of comparative protein structure models
STRINGQ9P769Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59431560S ribosomal protein L10
RefSeq mRNANM_001019738972h- 60S ribosomal protein L10 (rpl1002), mRNA
European Nucleotide ArchiveCAB88272ENA Protein Mapping
European Nucleotide ArchiveCAB88272.1ENA Protein Mapping
UniParcUPI0000133CD6UniProt Archive

Literature for rpl1002

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014