rpl1002 (SPAP7G5.05)


Gene Standard Namerpl1002 Characterisation Statuspublished
Systematic IDSPAP7G5.05 Feature Typeprotein coding
Synonymsrpl10, rpl10-2 Name Description
Product60S ribosomal protein L10 Product Size221aa, 25.36 kDa
Genomic Location Chromosome I, 3744043-3744906 (864nt); CDS:3744164-3744829 (666nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation465
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis338
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
increased cell population growth raterpl1002ΔNull247
viable vegetative cell populationrpl1002ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyrpl1002ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3744043..3744906
mRNA3744043..3744906
5' UTR3744043..3744163PMID:21511999
CDS3744164..3744829
3' UTR3744830..3744906PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00252 Pfam IPR016180 Ribosomal protein L10e/L16 5 166 3
PS01257 Prosite Patterns IPR018255 Ribosomal protein L10e, conserved site 108 129 2
PTHR11726 HMMPANTHER 2 217 2
3.90.1170.10 Gene3D IPR016180 Ribosomal protein L10e/L16 4 173 3
SSF54686 SuperFamily IPR016180 Ribosomal protein L10e/L16 4 173 3
PIRSF005590 PIRSF IPR001197 Ribosomal protein L10e 1 182 2
TIGR00279 tigrfam IPR001197 Ribosomal protein L10e 1 172 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.75 Da
Charge 25.50
Isoelectric point 10.61
Molecular weight 25.36 kDa
Number of residues 221
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
86913.59during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
4545.43during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
50during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
4.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4603
conserved in eukaryotes4514
conserved in bacteria1001
conserved in metazoa3424
conserved in vertebrates3399
conserved in archaea238
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bynak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withago1argonaute Positive GeneticPMID:22681890
negative genetic interaction withapc10anaphase-promoting complex substrate recognition subunit Apc10 Negative GeneticPMID:22681890
negative genetic interaction withdad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
negative genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
negative genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
negative genetic interaction withduo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
synthetic lethal withfan1Fanconi-associated nuclease Fan1 Synthetic LethalityPMID:24192486
negative genetic interaction withhri1eIF2 alpha kinase Hri1 Negative GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:22681890
positive genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
negative genetic interaction withppk14serine/threonine protein kinase Ppk14 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
negative genetic interaction withrad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
negative genetic interaction withres1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
negative genetic interaction withSPBC19G7.04HMG box protein Negative GeneticPMID:22681890
negative genetic interaction withsre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
negative genetic interaction withsre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:22681890
negative genetic interaction withsrp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
negative genetic interaction withusp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAP7G5.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAP7G5.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAP7G5.05 BioGRID Interaction Datasets
Expression Viewer SPAP7G5.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAP7G5.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAP7G5.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAP7G5.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAP7G5.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAP7G5.05 Transcriptome Viewer (Bähler Lab)
GEO SPAP7G5.05 GEO profiles
PInt SPAP7G5.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAP7G5.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAP7G5.05 Fission yeast phenotypic data & analysis
Cyclebase SPAP7G5.05.1 Cell Cycle Data
UniProtKB/SwissProtQ9P76960S ribosomal protein L10-B
ModBaseQ9P769Database of comparative protein structure models
STRINGQ9P769Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59431560S ribosomal protein L10
RefSeq mRNANM_001019738972h- 60S ribosomal protein L10 (rpl1002), mRNA
European Nucleotide ArchiveCAB88272.1ENA Protein Mapping
UniParcUPI0000133CD6UniProt Archive

Literature for rpl1002

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015