rps602 (SPAPB1E7.12)

Gene Standard Namerps602 Characterisation Statusbiological_role_inferred
Systematic IDSPAPB1E7.12 Feature Typeprotein coding
Synonymsrps6, rps6-2 Name Description
Product40S ribosomal protein S6 (predicted) Product Size239aa, 27.48 kDa
Genomic Location Chromosome I, 3319189-3320060 (872nt); CDS:3319260-3319979 (720nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation465
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis338
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit65
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationrps602ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyrps602ΔNull3094
Target Of
FYPO affected by mutation in isp7 2-OG-Fe(II) oxygenase superfamily protein
FYPO affected by mutation in npr2 SEA/Iml1/Npr2/3 complex subunit Npr2 (predicted)
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR3319189..3319259PMID:21511999
3' UTR3319980..3320060PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01092 Pfam IPR001377 Ribosomal protein S6e 1 126 2
PS00578 Prosite Patterns IPR018282 Ribosomal protein S6e, conserved site 52 63 2
PTHR11502:SF6 HMMPANTHER 2 239 2
PTHR11502 HMMPANTHER IPR001377 Ribosomal protein S6e 2 239 2
PIRSF002129 PIRSF IPR014401 Ribosomal protein S6, eukaryotic 1 239 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.96 Da
Charge 34.00
Isoelectric point 11.44
Molecular weight 27.48 kDa
Number of residues 239

Protein Modifications

Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
98391.89during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
8129.28during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
120during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
8.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in archaea238

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bycid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
affinity captured bygad8AGC family protein kinase Gad8 Affinity Capture-MSPMID:23213482
binds DNA-binding domain construct withish1LEA domain protein Two-hybridPMID:11751918
binds activation domain construct withnap2nucleosome assembly protein Nap2 Two-hybridPMID:23695164
modified bypsk1serine/threonine protein kinase Psk1 Biochemical ActivityPMID:22976295
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
enhances phenotype ofrps60140S ribosomal protein S6 Phenotypic EnhancementPMID:20144990
External References
Database Identifier Description
NBRP SPAPB1E7.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAPB1E7.12 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAPB1E7.12 BioGRID Interaction Datasets
Expression Viewer SPAPB1E7.12 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAPB1E7.12 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAPB1E7.12 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAPB1E7.12 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAPB1E7.12 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAPB1E7.12 Transcriptome Viewer (Bähler Lab)
GEO SPAPB1E7.12 GEO profiles
PInt SPAPB1E7.12 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAPB1E7.12 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAPB1E7.12 Fission yeast phenotypic data & analysis
Cyclebase SPAPB1E7.12.1 Cell Cycle Data
UniProtKB/SwissProtQ9C0Z740S ribosomal protein S6-B
ModBaseQ9C0Z7Database of comparative protein structure models
STRINGQ9C0Z7Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59413840S ribosomal protein S6
RefSeq mRNANM_001019562972h- 40S ribosomal protein S6 (rps602), mRNA
European Nucleotide ArchiveCAC36929.1ENA Protein Mapping
UniParcUPI0000135088UniProt Archive

Literature for rps602

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015