rps602 (SPAPB1E7.12)

Gene Standard Namerps602 Characterisation Statusbiological_role_inferred
Systematic IDSPAPB1E7.12 Feature Typeprotein coding
Synonymsrps6, rps6-2 Name Description
Product40S ribosomal protein S6 (predicted) Product Size239aa, 27.48 kDa
Genomic Location Chromosome I, 3319189-3320060 (872nt); CDS:3319260-3319979 (720nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000006011GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0042254ribosome biogenesisISOSGD:S000005693GO_REF:0000024327
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0022627cytosolic small ribosomal subunitISOSGD:S000006011GO_REF:000002463
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrps602ΔNullPECO:0000005, PECO:0000137PMID:236978063755

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopyrps602ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01092 Pfam IPR001377 Ribosomal protein S6e 1 126 2
PS00578 Prosite Patterns IPR018282 Ribosomal protein S6e 52 63 2
PTHR11502 HMMPANTHER IPR001377 Ribosomal protein S6e 1 239 2
Low complexity (SEG) seg 67 78
Low complexity (SEG) seg 216 234
PIRSF002129 PIRSF IPR014401 Ribosomal protein S6, eukaryotic 1 239 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.96 Da
Charge 34.00
Isoelectric point 11.44
Molecular weight 27.48 kDa
Number of residues 239

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residueIDAPMID:239348891192
present_during single-celled organism vegetative growth phase
absent_during cellular response to nitrogen starvationIDAPMID:23934889
absent_during cellular response to rapamycinIDAPMID:23934889
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
98391.89during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
8129.28during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
8.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
120during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in archaea237

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rps60140S ribosomal protein S6 Phenotypic EnhancementPMID:20144990
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
ish1LEA domain protein Two-hybridPMID:11751918
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
nap2nucleosome assembly protein Nap2 (predicted) Two-hybridPMID:23695164
psk1serine/threonine protein kinase Psk1 Biochemical ActivityPMID:22976295
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
gad8AGC family protein kinase Gad8 Affinity Capture-MSPMID:23213482
External References
Database Identifier Description
NBRP SPAPB1E7.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAPB1E7.12 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAPB1E7.12 BioGRID Interaction Datasets
Expression Viewer SPAPB1E7.12 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAPB1E7.12 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAPB1E7.12 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAPB1E7.12 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAPB1E7.12 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAPB1E7.12 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAPB1E7.12 Cell Cycle Data
GEO SPAPB1E7.12 GEO profiles
PInt SPAPB1E7.12 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene254358140S ribosomal protein S6
EntrezGene254358140S ribosomal protein S6
UniProtKB/SwissProtQ9C0Z740S ribosomal protein S6-B
ModBaseQ9C0Z7Database of comparative protein structure models
StringQ9C0Z7Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59413840S ribosomal protein S6
RefSeq mRNANM_001019562972h- 40S ribosomal protein S6 (rps602), mRNA
European Nucleotide ArchiveCAC36929ENA Protein Mapping
UniParcUPI0000135088UniProt Archive

Literature for rps602

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014