rps002 (SPAPJ698.02c)


Gene Standard Namerps002 Characterisation Statuspublished
Systematic IDSPAPJ698.02c Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S0B Product Size287aa, 31.42 kDa
Genomic Location Chromosome I, 4037624-4036533 (1092nt); CDS:4037586-4036723 (864nt)

Ensembl Gene Location
  1. mak2
  2. rfc3
  3. rps002
  4. prp12
  5. cut20
GO Molecular Function
Term NameCount
protein binding862
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation469
Annotation ExtensionEvidenceWith/FromReference
ribosomal small subunit assembly5
Annotation ExtensionEvidenceWith/FromReference
ribosomal small subunit biogenesis55
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit64
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationrps002Δ3831

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyrps002Δ3099
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4037624..4036533
5' UTR4037624..4037587PMID:21511999
3' UTR4036722..4036533AU007799
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00318 Pfam IPR001865 Ribosomal protein S2 21 116 3
PF00318 Pfam IPR001865 Ribosomal protein S2 118 185 3
PF16122 Pfam IPR032281 40S ribosomal protein SA, C-terminal domain 205 285 2
PS00963 Prosite Patterns IPR018130 Ribosomal protein S2, conserved site 122 146 2
PTHR11489 HMMPANTHER IPR005707 Ribosomal protein S2, eukaryotic/archaeal 6 265 2
3.40.50.10490 Gene3D Ribosomal protein S2, conserved site 35 218 5
SSF52313 SuperFamily IPR023591 Ribosomal protein S2, flavodoxin-like domain 15 203 3
Coil ncoils Predicted coiled-coil protein (DUF2205) 213 233 1050
MF_03015 hamap IPR027498 Ribosomal protein S2, eukaryotic 5 273 2
PR00395 PRINTS IPR001865 Ribosomal protein S2 18 36 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 48 57 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 97 114 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 122 139 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 139 150 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 160 174 3
TIGR01012 tigrfam IPR005707 Ribosomal protein S2, eukaryotic/archaeal 16 208 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.48 Da
Charge -9.50
Codon Adaptation Index 0.73
Isoelectric point 4.70
Molecular weight 31.42 kDa
Number of residues 287
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1675
present during cellular response to thiabendazoleT107
present during cellular response to thiabendazole, mitotic M phaseS46
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S46 PMID:21712547
present during cellular response to thiabendazole IDA S46 PMID:18257517
present during cellular response to thiabendazole IDA T107 PMID:18257517
phosphorylated residue 1930
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
ubiquitinylated lysineK60 512
Annotation ExtensionEvidenceResidueReference
IDA PMID:26412298
mass spectrometry evidence K60 PMID:26412298
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rps002 (SPAPJ698.02c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
664270during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
655292during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
670801during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
631216during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
247523.34during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
627915during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
55243.82during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
120during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
10during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3422
conserved in vertebrates3397
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load gene that interact physically with SPAPJ698.02c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds activation domain construct withcda1chitin deacetylase Cda1 Two-hybridPMID:15862318
affinity capturescda1chitin deacetylase Cda1 Affinity Capture-WesternPMID:15862318
Genetic Interactions

Source: BioGRID

Load gene that interact genetically with SPAPJ698.02c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withpyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
negative genetic interaction withrad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
negative genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
negative genetic interaction withSPAC1093.03inositol polyphosphate phosphatase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfml2ATP-dependent 3' to 5' DNA helicase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Positive GeneticPMID:22681890
positive genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
positive genetic interaction withprw1Clr6 histone deacetylase complex subunit Prw1 Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAPJ698.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAPJ698.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAPJ698.02c BioGRID Interaction Datasets
Expression Viewer SPAPJ698.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAPJ698.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAPJ698.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAPJ698.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAPJ698.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAPJ698.02c Transcriptome Viewer (Bähler Lab)
GEO SPAPJ698.02c GEO profiles
PInt SPAPJ698.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAPJ698.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAPJ698.02c Fission yeast phenotypic data & analysis
Cyclebase SPAPJ698.02c.1 Cell Cycle Data
UniProtKB/SwissProtQ9P54640S ribosomal protein S0-B
ModBaseQ9P546Database of comparative protein structure models
STRINGQ9P546Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59441340S ribosomal protein S0B
RefSeq mRNANM_001019843972h- 40S ribosomal protein S0B (rps002), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAB92099ENA Protein Mapping
UniParcUPI0000134B8FUniProt Archive

Literature for rps002

Search: Europe PMC or PubMed

Release Version: PomBase:30_57 - 27 Jan 2016