idi1 (SPBC106.15)


Gene Standard Nameidi1 Characterisation Statuspublished
Systematic IDSPBC106.15 Feature Typeprotein coding
Synonyms Name Description
Productisopentenyl-diphosphate delta-isomerase Idi1 Product Size229aa, 27.11 kDa
Genomic Location Chromosome II, 406839-407908 (1070nt); CDS:406868-407677 (810nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0016787hydrolase activityIEAIPR000086GO_REF:0000002842
GO:0004452isopentenyl-diphosphate delta-isomerase activityIDAPMID:77447661
ISOSGD:S000006038GO_REF:0000024
GO:0046872metal ion bindingIEAUniProtKB-KW:KW-0479GO_REF:0000037747
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0050992dimethylallyl diphosphate biosynthetic processIEA UniPathway:UPA00059GO_REF:00000411
GO:0006696ergosterol biosynthetic processISOSGD:S000006038GO_REF:000002439
GO:0008299isoprenoid biosynthetic processIEAUniProtKB-KW:KW-0414GO_REF:000003714
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolISOSGD:S000006038GO_REF:00000242317
IDAPMID:16823372
GO:0005634nucleusIDAPMID:168233722730
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyidi1ΔNullPMID:204732891309
Microscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002280inviable after spore germination, single cell divisionMicroscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:2369780656
FYPO:0000310inviable after spore germination, without cell division, with normal germ tube morphologyMicroscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:23697806303
FYPO:0002151inviable sporeMicroscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:23697806447
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1406839406991
2407056407394
3407451407908

UTRs

Region Start End Reference
five_prime_UTR406839406867PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00293 Pfam IPR000086 NUDIX hydrolase domain 54 201 8
PS51462 Prosite Profiles IPR000086 NUDIX hydrolase domain 52 202 8
PTHR10885:SF0 HMMPANTHER 3 229 1
PTHR10885 HMMPANTHER IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 3 229 1
G3DSA:3.90.79.10 Gene3D IPR015797 16 222 9
SSF55811 SuperFamily IPR015797 22 215 9
PIRSF018427 PIRSF IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 2 226 1
TIGR02150 tigrfam IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 24 204 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 118.38 Da
Charge -4.50
Isoelectric point 5.59
Molecular weight 27.11 kDa
Number of residues 229
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
25041.08during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
7160.83during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
4.2during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.52during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Complementation
DescriptionQualifierReferenceCount
functionally complements S. cerevisiae IDI1full PMID:77447661
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999426
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in bacteria1001
conserved in metazoa3419
conserved in vertebrates3394
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC106.15 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC106.15 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC106.15 BioGRID Interaction Datasets
Expression Viewer SPBC106.15 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC106.15 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC106.15 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC106.15 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC106.15 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC106.15 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC106.15 Cell Cycle Data
GEO SPBC106.15 GEO profiles
PInt SPBC106.15 Protein-Protein Interaction Predictor (Bähler Lab)
IntEnz5.3.3.2Integrated relational Enzyme database
Rhea5.3.3.2Annotated reactions database
EntrezGene2540174isopentenyl-diphosphate delta-isomerase Idi1
WikiGene2540174isopentenyl-diphosphate delta-isomerase Idi1
SPD / RIKEN10/10C01Orfeome Localization Data
UniProtKB/SwissProtQ10132Isopentenyl-diphosphate Delta-isomerase
ModBaseQ10132Database of comparative protein structure models
StringQ10132Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595164isopentenyl-diphosphate delta-isomerase Idi1
RefSeq mRNANM_001021073972h- isopentenyl-diphosphate delta-isomerase Idi1 (idi1), mRNA
European Nucleotide ArchiveAAA80596ENA Protein Mapping
European Nucleotide ArchiveCAB53731ENA Protein Mapping
UniParcUPI000228F492UniProt Archive

Literature for idi1

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014