idi1 (SPBC106.15)


Gene Standard Nameidi1 Characterisation Statuspublished
Systematic IDSPBC106.15 Feature Typeprotein coding
Synonyms Name Description
Productisopentenyl-diphosphate delta-isomerase Idi1 Product Size229aa, 27.11 kDa
Genomic Location Chromosome II, 406839-407908 (1070nt); CDS:406868-407677 (810nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0016787hydrolase activityIEAIPR000086GO_REF:0000002845
GO:0004452isopentenyl-diphosphate delta-isomerase activityISOSGD:S000006038GO_REF:00000241
IDAPMID:7744766
GO:0046872metal ion bindingIEAUniProtKB-KW:KW-0479GO_REF:0000037748
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0050992dimethylallyl diphosphate biosynthetic processIEA UniPathway:UPA00059GO_REF:00000411
GO:0006696ergosterol biosynthetic processISOSGD:S000006038GO_REF:000002439
GO:0008299isoprenoid biosynthetic processIEAUniProtKB-KW:KW-0414GO_REF:000003715
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722319
ISOSGD:S000006038GO_REF:0000024
GO:0005634nucleusIDAPMID:168233722737
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyidi1ΔNullPMID:204732891337
Microscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002280inviable after spore germination, single cell divisionMicroscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:2369780660
FYPO:0000310inviable after spore germination, without cell division, with normal germ tube morphologyMicroscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:23697806303
FYPO:0002151inviable sporeMicroscopyidi1ΔNullPECO:0000005, PECO:0000137PMID:23697806462
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1406839406991
2407056407394
3407451407908
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00293 Pfam IPR000086 NUDIX hydrolase domain 54 201 8
PS51462 Prosite Profiles IPR000086 NUDIX hydrolase domain 52 202 8
PTHR10885 HMMPANTHER IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 3 229 1
PTHR10885:SF0 HMMPANTHER 3 229 1
3.90.79.10 Gene3D IPR015797 NUDIX hydrolase domain-like 16 222 9
SSF55811 SuperFamily IPR015797 NUDIX hydrolase domain-like 22 215 9
PIRSF018427 PIRSF IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 2 226 1
TIGR02150 tigrfam IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 24 204 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 118.38 Da
Charge -4.50
Isoelectric point 5.59
Molecular weight 27.11 kDa
Number of residues 229
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
113739during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
124780during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
122510during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
116611during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
25041.08during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
115206during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
7160.83during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.2during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.52during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Complementation
DescriptionQualifierReference
functionally complements S. cerevisiae IDI1full PMID:7744766
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999432
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4599
conserved in eukaryotes4514
conserved in bacteria1002
conserved in metazoa3428
conserved in vertebrates3402
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC106.15 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC106.15 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC106.15 BioGRID Interaction Datasets
Expression Viewer SPBC106.15 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC106.15 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC106.15 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC106.15 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC106.15 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC106.15 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC106.15 Cell Cycle Data
GEO SPBC106.15 GEO profiles
PInt SPBC106.15 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC106.15 Peptides identified in tandem mass spectrometry proteomics experiments
IntEnz5.3.3.2Integrated relational Enzyme database
Rhea5.3.3.2Annotated reactions database
SPD / RIKEN10/10C01Orfeome Localization Data
UniProtKB/SwissProtQ10132Isopentenyl-diphosphate Delta-isomerase
ModBaseQ10132Database of comparative protein structure models
STRINGQ10132Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595164isopentenyl-diphosphate delta-isomerase Idi1
RefSeq mRNANM_001021073972h- isopentenyl-diphosphate delta-isomerase Idi1 (idi1), mRNA
European Nucleotide ArchiveU21154ENA EMBL mapping
European Nucleotide ArchiveCAB53731.2ENA Protein Mapping
MetaCycPWY-5123Trans, trans-farnesyl diphosphate biosynthesis
MetaCycPWY-6174Mevalonate pathway II (archaea)
MetaCycPWY-6383Mono-trans, poly-cis decaprenyl phosphate biosynthesis
MetaCycPWY-6859All-trans-farnesol biosynthesis
MetaCycPWY-7102Bisabolene biosynthesis
MetaCycPWY-922Mevalonate pathway I
UniParcUPI000228F492UniProt Archive
UniPathwayUPA00059Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1

Literature for idi1

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014