idi1 (SPBC106.15)

Gene Standard Nameidi1 Characterisation Statuspublished
Systematic IDSPBC106.15 Feature Typeprotein coding
Synonyms Name Description
Productisopentenyl-diphosphate delta-isomerase Idi1 Product Size229aa, 27.11 kDa
Genomic Location Chromosome II, 406839-407908 (1070nt); CDS:406868-407677 (810nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
hydrolase activity932
Annotation ExtensionEvidenceWith/FromReference
isopentenyl-diphosphate delta-isomerase activity1
Annotation ExtensionEvidenceWith/FromReference
metal ion binding743
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
dimethylallyl diphosphate biosynthetic process1
Annotation ExtensionEvidenceWith/FromReference
ergosterol biosynthetic process45
Annotation ExtensionEvidenceWith/FromReference
isoprenoid biosynthetic process16
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationidi1Δ1443

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, single cell divisionidi1Δ63
inviable after spore germination, without cell division, with normal germ tube morphologyidi1Δ303
inviable sporeidi1Δ474
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons406839..406991, 407056..407394, 407451..407908
Intron406992..407055, 407395..407450
5' UTR406839..406867PMID:21511999
CDS406868..406991, 407056..407394, 407451..407677
3' UTR407678..407908SP21154
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00293 Pfam IPR000086 NUDIX hydrolase domain 54 201 8
PS51462 Prosite Profiles IPR000086 NUDIX hydrolase domain 52 202 8
PTHR10885:SF0 HMMPANTHER 1 229 1
PTHR10885 HMMPANTHER IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 1 229 1 Gene3D IPR015797 NUDIX hydrolase domain-like 16 222 9
SSF55811 SuperFamily IPR015797 NUDIX hydrolase domain-like 22 215 9
PIRSF018427 PIRSF IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 3 225 1
TIGR02150 tigrfam IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 24 204 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 118.38 Da
Charge -4.50
Codon Adpatation Index 0.54
Isoelectric point 5.59
Molecular weight 27.11 kDa
Number of residues 229
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
113739during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
124780during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
122510during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
116611during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
25041.08during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
115206during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
7160.83during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.2during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.52during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
functionally complements S. cerevisiae IDI1full PMID:7744766
gene structure updated PMID:21511999433
Taxonomic Conservation
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3421
conserved in vertebrates3396

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPBC106.15 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC106.15 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC106.15 BioGRID Interaction Datasets
Expression Viewer SPBC106.15 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC106.15 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC106.15 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC106.15 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC106.15 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC106.15 Transcriptome Viewer (Bähler Lab)
GEO SPBC106.15 GEO profiles
PInt SPBC106.15 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC106.15 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC106.15 Fission yeast phenotypic data & analysis
Cyclebase SPBC106.15.1 Cell Cycle Data
IntEnz5.3.3.2Integrated relational Enzyme database
Rhea5.3.3.2Annotated reactions database
SPD / RIKEN10/10C01Orfeome Localization Data
UniProtKB/SwissProtQ10132Isopentenyl-diphosphate Delta-isomerase
ModBaseQ10132Database of comparative protein structure models
STRINGQ10132Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595164isopentenyl-diphosphate delta-isomerase Idi1
RefSeq mRNANM_001021073972h- isopentenyl-diphosphate delta-isomerase Idi1 (idi1), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveU21154ENA EMBL mapping
European Nucleotide ArchiveAAA80596ENA Protein Mapping
European Nucleotide ArchiveCAB53731ENA Protein Mapping
European Nucleotide ArchiveCAB53731.2ENA Protein Mapping
MetaCycPWY-5123Trans, trans-farnesyl diphosphate biosynthesis
MetaCycPWY-6174Mevalonate pathway II (archaea)
MetaCycPWY-6383Mono-trans, poly-cis decaprenyl phosphate biosynthesis
MetaCycPWY-6859All-trans-farnesol biosynthesis
MetaCycPWY-7102Bisabolene biosynthesis
MetaCycPWY-7391Isoprene biosynthesis II (engineered)
MetaCycPWY-7524Mevalonate pathway III (archaea)
MetaCycPWY-7560Methylerythritol phosphate pathway II
MetaCycPWY-922Mevalonate pathway I
KEGG00900+ backbone biosynthesis
UniParcUPI000228F492UniProt Archive

Literature for idi1

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015