cys2 (SPBC106.17c)

Gene Standard Namecys2 ChromosomeII
Systematic IDSPBC106.17c Gene Start412795
Synonyms Gene End410720
Producthomoserine O-acetyltransferase (predicted) Gene Length2076
Feature Typeprotein coding CDS Start412634
Name Description CDS End411120
Characterisation Statuspublished CDS Length1515

Ensembl Gene Location
  1. sda1
  2. SPNCRNA.1354
  3. idi1
  4. pre6
  5. cys2
  6. SPNCRNA.1355
  7. rpl2501
  8. SPBC106.19
  9. exo70
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000037growth auxotrophic for cysteineno_name (unrecorded)unrecordedPMID:17622533
FYPO:0002060viable vegetative cell populationcys2delta (deletion)deletionPMID:12618370
Microscopycys2delta (deletion)deletionPMID:20473289
GO Molecular Function

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0004414homoserine O-acetyltransferase activityIEAIPR008220GO_REF:0000002
GO Biological Process

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0009086methionine biosynthetic processIEAIPR008220GO_REF:0000002
GO:0019344cysteine biosynthetic processIMPPMID:17622533
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmISSUniProtKB:P08465GO_REF:0000001
GO:0005739mitochondrionIDAPMID:16823372
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1412795410720

References

Region Start End Reference
three_prime_UTR411119410720PMID:21511999
five_prime_UTR412795412635PMID:21511999
three_prime_UTR411119410720PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00561 IPR000073 Pfam Alpha/beta hydrolase fold-1 158 395 5
G3DSA:3.40.50.1820 Gene3D 371 372 40
G3DSA:3.40.50.1820 Gene3D 100 287 40
G3DSA:3.40.50.1820 Gene3D 434 481 40
SSF53474 SuperFamily 422 501 42
SSF53474 SuperFamily 83 363 42
PIRSF000443 IPR008220 PIRSF Homoserine acetyltransferase 22 504 2
PTHR10992:SF262 hmmpanther 68 502 1
PTHR10992 hmmpanther 68 502 5
TIGR01392 IPR008220 tigrfam Homoserine acetyltransferase 87 371 2

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000646abhydrolase familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000646

Protein Properties

Ave. residue weight 111.83 Da
Charge 4.00
Isoelectric point 6.89
Molecular weight 56.36 kDa
Number of residues 504
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide40045.98PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide3486.84PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide15PMID:23101633
Experimental Tools
DescriptionQualifierReference
selectable marker, amino acid auxotroph PMID:17622533
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi
conserved in eukaryotes
conserved in bacteria
Contact Curators
External References
Database Identifier Description
NBRP SPBC106.17c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC106.17c Retrieval of eukaryotic orthologs
BioGrid SPBC106.17c BioGRID Interaction Datasets
Bähler Lab SPBC106.17c Cell Cycle Expression Profile
Bähler Lab SPBC106.17c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC106.17c Pheromone response/mating expression profiles
Bähler Lab SPBC106.17c Environmental stress expression profiles
Bähler Lab SPBC106.17c Bähler Lab Transcriptome Viewer
Cyclebase SPBC106.17c Cell Cycle Data
PInt SPBC106.17c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC106.17c Entrez Gene
WikiGene2539905homoserine O-acetyltransferase (predicted)
Uniprot_genenameCYS2
EntrezGene2539905homoserine O-acetyltransferase (predicted)
IntEnz2.3.1.-
UniProtKB/SwissProtQ10341Probable serine-O-acetyltransferase cys2
ModBaseQ10341Database of comparative protein structure models
Pfam Protein DomainsQ10341Pfam Domain Arrangement
RefSeq PeptideNP_595166homoserine O-acetyltransferase (predicted)
RefSeq mRNANM_001021075972h- homoserine O-acetyltransferase (predicted) (cys2), mRNA
European Nucleotide ArchiveCAB53733ENA Protein Mapping
SPD / RIKEN44/44H01Orfeome Localization Data
UniParcUPI000013A3ACUniProt Archive

Literature for cys2
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013