SPBC1198.01

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC1198.01 Gene Start172378
Synonyms Gene End174315
Productglutathione-dependent formaldehyde dehydrogenase (predicted) Gene Length1938
Feature Typeprotein coding CDS Start172991
Name Description CDS End174262
Characterisation Statusbiological_role_inferred CDS Length1272

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPBC1198.01delta (deletion)deletionPMID:20473289
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0008270zinc ion bindingIEAIPR002085, IPR013149, IPR002328GO_REF:0000002
GO:0016491oxidoreductase activityIEAUniProtKB:KW-0560GO_REF:0000037
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0005794Golgi apparatusIDAPMID:16823372
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1172378174315

References

Region Start End Reference
five_prime_UTR172378172990PMID:21511999
three_prime_UTR174263174315PMID:21511999
three_prime_UTR174263174315PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF08240 IPR013154 Pfam Alcohol dehydrogenase GroES-like 61 188 9
PF00107 IPR013149 Pfam Alcohol dehydrogenase, C-terminal 232 308 12
PS00059 IPR002328 Prosite Patterns Alcohol dehydrogenase, zinc-type, conserved site 96 110 5
G3DSA:3.90.180.10 Gene3D 35 222 12
G3DSA:3.40.50.720 IPR016040 Gene3D 223 376 98
SSF51735 SuperFamily 201 383 88
SSF50129 IPR011032 SuperFamily 36 215 13
PTHR11695 IPR002085 hmmpanther Alcohol dehydrogenase superfamily, zinc-type 1 418 12
PTHR11695:SF281 hmmpanther 1 418 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.79 Da
Charge -7.00
Isoelectric point 5.44
Molecular weight 46.44 kDa
Number of residues 423
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide1977.3PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014
population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide0.67PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide0.55PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi
conserved in eukaryotes
Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
hip1hira protein, histone chaperone Hip1 Positive GeneticPMID:22681890
srb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Positive GeneticPMID:22681890
pob3FACT complex subunit Pob3 Negative GeneticPMID:22681890
ppk21serine/threonine protein kinase Ppk21 Positive GeneticPMID:22681890
SPAC17H9.13cglutamate 5-kinase (predicted) Positive GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Positive GeneticPMID:22681890
prw1Clr6 histone deacetylase complex subunit Prw1 Negative GeneticPMID:22681890
sep1forkhead transcription factor Sep1 Negative GeneticPMID:22681890
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
vps35retromer complex subunit Vps35 Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPBC1198.01 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1198.01 Retrieval of eukaryotic orthologs
BioGrid SPBC1198.01 BioGRID Interaction Datasets
Bähler Lab SPBC1198.01 Cell Cycle Expression Profile
Bähler Lab SPBC1198.01 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1198.01 Pheromone response/mating expression profiles
Bähler Lab SPBC1198.01 Environmental stress expression profiles
Bähler Lab SPBC1198.01 Bähler Lab Transcriptome Viewer
Cyclebase SPBC1198.01 Cell Cycle Data
PInt SPBC1198.01 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1198.01 Entrez Gene
WikiGene2540059glutathione-dependent formaldehyde dehydrogenase (predicted)
EntrezGene2540059glutathione-dependent formaldehyde dehydrogenase (predicted)
SPD / RIKEN20/20D04Orfeome Localization Data
UniProtKB/SwissProtQ9P6I8Zinc-type alcohol dehydrogenase-like protein C1198.01
ModBaseQ9P6I8Database of comparative protein structure models
Pfam Protein DomainsQ9P6I8Pfam Domain Arrangement
RefSeq PeptideNP_595070glutathione-dependent formaldehyde dehydrogenase (predicted)
RefSeq mRNANM_001020976972h- glutathione-dependent formaldehyde dehydrogenase (predicted) (SPBC1198.01), mRNA
European Nucleotide ArchiveCAB91176ENA Protein Mapping
UniParcUPI0000069AC0UniProt Archive

Literature for SPBC1198.01

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013