tfg2 (SPBC1198.13c)

Gene Standard Nametfg2 ChromosomeII
Systematic IDSPBC1198.13c Gene Start197189
SynonymsSPBC660.03c Gene End194038
Producttranscription factor TFIIF complex beta subunit Tfg2 (predicted) Gene Length3152
Feature Typeprotein coding CDS Start197075
Name Description CDS End195990
Characterisation Statusbiological_role_inferred CDS Length1086

Ensembl Gene Location
  1. SPBC1198.08
  2. slm5
  3. ubc16
  4. reb1
  5. tfg2
  6. mfr1
  7. SPNCRNA.1324
  8. fbp1
  9. SPNCRNA.1325
  10. SPNCRNA.1326
  11. SPBC660.05
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopytfg2delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0000991core RNA polymerase II binding transcription factor activityISSUniProtKB:P41896GO_REF:0000001
GO:0003677DNA bindingIEAUniProtKB:KW-0238GO_REF:0000037
GO:0004003ATP-dependent DNA helicase activityISMPFAM:PF02270GO_REF:0000001
GO:0005524ATP bindingISMPFAM:PF02270GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006355regulation of transcription, DNA-dependentIEAUniProtKB:KW-0805GO_REF:0000037
GO:0006367transcription initiation from RNA polymerase II promoterISSUniProtKB:P41896GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005674transcription factor TFIIF complexISSUniProtKB:P41896GO_REF:0000001
GO:0044732mitotic spindle pole bodyIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1197189196551
2196491196348
3196244194038

References

Region Start End Reference
five_prime_UTR197189197076PMID:21511999
three_prime_UTR195989194038PMID:21511999
three_prime_UTR195989194038PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF02270 IPR003196 Pfam Transcription initiation factor IIF, beta subunit 21 253 1
G3DSA:1.10.10.10 IPR011991 Gene3D 190 253 43
SSF50916 IPR011039 SuperFamily 17 124 2
SSF46785 SuperFamily 189 254 49
PTHR10445:SF0 hmmpanther 1 290 1
PTHR10445 IPR003196 hmmpanther Transcription initiation factor IIF, beta subunit 1 290 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.78 Da
Charge -7.00
Isoelectric point 4.88
Molecular weight 34.62 kDa
Number of residues 307
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide3533.66PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide880.94PMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide3PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
rpb3RNA polymerase II subunit 3 Affinity Capture-MSPMID:11839823
Co-purificationPMID:15620689
tfg3transcription factor TFIIF complex subunit Tfg3 Affinity Capture-WesternPMID:15616156
rpc10DNA-directed RNA polymerase I, II and III subunit Rpc10 Affinity Capture-WesternPMID:15743411
fcp1CTD phosphatase Fcp1 Affinity Capture-MSPMID:11839823
Affinity Capture-WesternPMID:15616156
rpb5DNA-directed RNA polymerase I, II and III subunit Rpb5 Affinity Capture-WesternPMID:15743411
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External References
Database Identifier Description
NBRP SPBC1198.13c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1198.13c Retrieval of eukaryotic orthologs
BioGrid SPBC1198.13c BioGRID Interaction Datasets
Bähler Lab SPBC1198.13c Cell Cycle Expression Profile
Bähler Lab SPBC1198.13c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1198.13c Pheromone response/mating expression profiles
Bähler Lab SPBC1198.13c Environmental stress expression profiles
Bähler Lab SPBC1198.13c Bähler Lab Transcriptome Viewer
Cyclebase SPBC1198.13c Cell Cycle Data
PInt SPBC1198.13c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1198.13c Entrez Gene
EntrezGene2539924transcription factor TFIIF complex beta subunit Tfg2 (predicted)
Uniprot_genenameTFG2
WikiGene2539924transcription factor TFIIF complex beta subunit Tfg2 (predicted)
UniProtKB/SwissProtO94424Transcription initiation factor IIF subunit beta
ModBaseO94424Database of comparative protein structure models
Pfam Protein DomainsO94424Pfam Domain Arrangement
RefSeq PeptideNP_595082transcription factor TFIIF complex beta subunit Tfg2 (predicted)
RefSeq mRNANM_001020988972h- transcription factor TFIIF complex beta subunit Tfg2 (predicted) (tfg2), mRNA
European Nucleotide ArchiveCAB91188ENA Protein Mapping
SPD / RIKEN16/16H07Orfeome Localization Data
UniParcUPI000006BB4AUniProt Archive

Literature for tfg2
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013