his3 (SPBC11B10.02c)

Gene Standard Namehis3 ChromosomeII
Systematic IDSPBC11B10.02c Gene Start1489773
Synonymspi009, SPACTOKYO_453.27 Gene End1488036
Producthistidinol-phosphate aminotransferase imidazole acetol phosphate transaminase His3 Gene Length1738
Feature Typeprotein coding CDS Start1489664
Name Description CDS End1488211
Characterisation Statuspublished CDS Length1454

Ensembl Gene Location
  1. mok12
  2. alg2
  3. his3
  4. SPNCRNA.1437
  5. cog8
  6. mrps28
  7. rsp1
  8. sws1
  9. ivn1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyhis3delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004400histidinol-phosphate transaminase activityIEAEC:2.6.1.9GO_REF:0000003
GO:0030170pyridoxal phosphate bindingIEAIPR004839, IPR015422, IPR015421GO_REF:0000002
GO:0080130L-phenylalanine:2-oxoglutarate aminotransferase activityIEAEC:2.6.1.9GO_REF:0000003
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000105histidine biosynthetic processIEAUniProtKB:KW-0368GO_REF:0000037
GO:0010045response to nickel cationIMPPMID:10748059
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
114897731489597
214895411489530
314893441488733
414886731488036

References

Region Start End Reference
three_prime_UTR14882101488036PMID:21511999
three_prime_UTR14882101488036PMID:21511999
five_prime_UTR14897731489665PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00155 IPR004839 Pfam Aminotransferase, class I/classII 45 373 11
PS00599 IPR001917 Prosite Patterns Aminotransferase, class-II, pyridoxal-phosphate binding site 220 229 3
G3DSA:3.90.1150.10 IPR015422 Gene3D 254 374 23
G3DSA:3.40.640.10 IPR015421 Gene3D 48 253 31
SSF53383 IPR015424 SuperFamily 17 374 31
PTHR11751 hmmpanther 2 384 6
PTHR11751:SF3 hmmpanther 2 384 1
TIGR01141 IPR005861 tigrfam Histidinol-phosphate aminotransferase family 9 374 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744
PMID:18257517

Protein Properties

Ave. residue weight 111.29 Da
Charge -1.50
Isoelectric point 5.89
Molecular weight 42.73 kDa
Number of residues 384
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide28190.3PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide17001.41PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide13PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.9PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in bacteria
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPBC11B10.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC11B10.02c Retrieval of eukaryotic orthologs
BioGrid SPBC11B10.02c BioGRID Interaction Datasets
Bähler Lab SPBC11B10.02c Cell Cycle Expression Profile
Bähler Lab SPBC11B10.02c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC11B10.02c Pheromone response/mating expression profiles
Bähler Lab SPBC11B10.02c Environmental stress expression profiles
Bähler Lab SPBC11B10.02c Bähler Lab Transcriptome Viewer
Cyclebase SPBC11B10.02c Cell Cycle Data
PInt SPBC11B10.02c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC11B10.02c Entrez Gene
WikiGene2539698histidinol-phosphate aminotransferase imidazole acetol phosphate transaminase His3
Uniprot_genenameHIS3
EntrezGene2539698histidinol-phosphate aminotransferase imidazole acetol phosphate transaminase His3
IntEnz2.6.1.9
SPD / RIKEN50/50G02Orfeome Localization Data
UniProtKB/SwissProtP36605Histidinol-phosphate aminotransferase
ModBaseP36605Database of comparative protein structure models
Pfam Protein DomainsP36605Pfam Domain Arrangement
RefSeq PeptideNP_595622histidinol-phosphate aminotransferase imidazole acetol phosphate transaminase His3
RefSeq mRNANM_001021516972h- histidinol-phosphate aminotransferase imidazole acetol phosphate transaminase His3 (his3), mRNA
European Nucleotide ArchiveAAA67316ENA Protein Mapping
European Nucleotide ArchiveAAA86664ENA Protein Mapping
European Nucleotide ArchiveBAA21386ENA Protein Mapping
European Nucleotide ArchiveCAC37506ENA Protein Mapping
UniParcUPI000012C89DUniProt Archive

Literature for his3
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013