pht1 (SPBC11B10.10c)

Synonymspi001 ChromosomeII
Producthistone H2A variant H2A.Z, Pht1 Gene Start1503468
Feature Typeprotein coding Gene End1502203
Name Description CDS Start1503061
Characterisation Statuspublished CDS End1502642

Ensembl Gene Location
rsp1 sws1 ivn1 prl24 SPBC11B10.08 SPNCRNA.1438 cdc2 > pht1 < SPBTRNATHR.06 SPRRNA.33 shy1 naa25 SPNCRNA.351 ucp8
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
115034681502203

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF00125 Pfam Histone core 27 100 79.7 12
47113 Superfamily 11 108 128.4 26
SM00414 Smart Histone H2A 11 131 246.5 3
PS00046 scanprosite Histone H2A 30 36 3
PR00620 Prints Histone H2A 108 126 58.45 3
PR00620 Prints Histone H2A 67 80 90.54 3
PR00620 Prints Histone H2A 52 67 70.77 3
PR00620 Prints Histone H2A 81 95 65.78 3
PR00620 Prints Histone H2A 22 44 62.32 3

Protein Properties

Ave. residue weight 108.10 Da
Charge 12.00
Isoelectric point 10.78
Molecular weight 15.03 kDa
Number of residues 139
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

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Biological Process
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0006338chromatin remodelingIPI GO:0031011Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006338
GO:0043486histone exchangeIPI GO:0000812Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0043486
GO:0051276chromosome organizationIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0051276

Cellular Component
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000812Swr1 complexIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000812
GO:0005634nucleusIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005634
GO:0005739mitochondrionIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005739
GO:0031011Ino80 complexIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0031011

Gene Expression

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DescriptionSourceAll Genes
deletion mutant expression profiling Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000206

Warning

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DescriptionSourceAll Genes
gene structure updated Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000070

Protein Family

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DescriptionSourceAll Genes
histone foldTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000297

Species Distribution

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DescriptionSourceAll Genes
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in Eukaryotes onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000096
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094

Manually Curated Orthologs

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SpeciesGeneDescription

Interactions

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Genetic Interactions from BioGRID

Gene Feature Evidence Source
SPBC337.03RNA polymerase II transcription termination factor (predicted) Synthetic Growth Defect
SPAC4F10.04protein phosphatase type 2A, intrinsic regulator (predicted) Negative Genetic
cwf21complexed with Cdc5 protein Cwf21 Negative Genetic
SPAC637.06alpha-1,2-galactosyltransferase (predicted) Positive Genetic
clr4histone H3 methyltransferase Clr4 Negative Genetic
sdc1Dpy-30 domain protein Sdc1 Negative Genetic
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Negative Genetic
rok1ATP-dependent RNA helicase Rok1 (predicted) Negative Genetic
est1telomerase regulator Est1 Negative Genetic
fin1serine/threonine protein kinase, NIMA related Fin1 Synthetic Growth Defect
Negative Genetic
ash2Ash2-trithorax family protein Synthetic Growth Defect
Negative Genetic
set1histone lysine methyltransferase Set1 Negative Genetic
mst2histone acetyltransferase Mst2 Negative Genetic
rap1telomere binding protein Rap1 Negative Genetic
mph1dual specificity protein kinase Mph1 Negative Genetic
hip1hira protein, histone chaperone Hip1 Synthetic Growth Defect
Negative Genetic
mcl1DNA polymerase alpha accessory factor Mcl1 Negative Genetic
SPAC26H5.05IPT/TIG ankyrin repeat containing transcription regulator of fatty acid biosynthesis (predicted) Negative Genetic
SPCC1919.13cribosome biogenesis protein (predicted) Negative Genetic
spc34DASH complex subunit Spc34 Negative Genetic
alp16gamma tubulin complex subunit Alp16 Negative Genetic
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative Genetic
pmc2mediator complex subunit Pmc2/Med1 Negative Genetic
med7mediator complex subunit Med7 Negative Genetic
aut12autophagy associated protein Aut12 (predicted) Negative Genetic
ase1antiparallel microtubule cross-linking factor Ase1 Positive Genetic
SPBC1861.07elongin C (predicted) Negative Genetic
pmk1MAP kinase Pmk1 Negative Genetic
pof3F-box protein Pof3 Synthetic Growth Defect
rhp14XP-A family homolog Rhp14 Negative Genetic
SPACUNK4.16calpha,alpha-trehalose-phosphate synthase (predicted) Positive Genetic
dad2DASH complex subunit Dad2 Negative Genetic
spf1Set1C PHD Finger protein Spf1 Negative Genetic
dad1DASH complex subunit Dad1 Negative Genetic
arp42SWI/SNF and RSC complex subunit Arp42 Negative Genetic
pnk1DNA kinase/phosphatase Pnk1 Positive Genetic
caf1CCR4-Not complex CAF1 family ribonuclease subunit Caf1 Negative Genetic
swr1SNF2 family helicase Swr1 Positive Genetic
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative Genetic
bdc1bromodomain containing protein 1, Bdc1 Negative Genetic
mis6inner centromere protein, CENP-I ortholog Mis6 Synthetic Growth Defect
pzh1serine/threonine protein phosphatase Pzh1 Phenotypic Enhancement
swc3Swr1 complex subunit Swc3 Positive Genetic
msh1mitochondrial MutS protein Msh1 (predicted) Positive Genetic
dsc1ubiquitin-protein ligase E3 (predicted) Negative Genetic
SPBC36B7.08cnucleosome assembly protein (predicted) Negative Genetic
set3histone lysine methyltransferase Set3 Negative Genetic
par1protein phosphatase regulatory subunit Par1 Negative Genetic
res2MBF transcription factor complex subunit Res2 Positive Genetic
ppk30Ark1/Prk1 family protein kinase Ppk30 Positive Genetic
swd3WD repeat protein Swd3 Negative Genetic
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative Genetic
SPAC23A1.19cRecQ type DNA helicase Hrq1 (predicted) Negative Genetic
asp1inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Phenotypic Enhancement
rsc1RSC complex subunit Rsc1 Phenotypic Enhancement
SPBC13E7.08cRNA polymerase II associated Paf1 complex (predicted) Synthetic Growth Defect
Negative Genetic
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative Genetic
rnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative Genetic
SPAC4H3.07cprotein phosphatase Fmp31 (predicted) Negative Genetic
pom1DYRK family protein kinase Pom1 Negative Genetic
ies2Ino80 complex subunit Ies2 Synthetic Growth Defect
Negative Genetic
for3formin For3 Synthetic Growth Defect
raf2Rik1-associated factor Raf2 Negative Genetic
mis12kinetochore protein Mis12 Synthetic Growth Defect
air1zinc knuckle TRAMP complex subunit Air1 Negative Genetic
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Phenotypic Enhancement
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative Genetic
ubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Positive Genetic
swc5Swr1 complex subunit Swc5 Positive Genetic
pho24-nitrophenylphosphatase Negative Genetic
hif2Set3 complex subunit Hif2 Negative Genetic
vps71Swr1 complex subunit Vps71 Positive Genetic
elp2elongator complex subunit Elp2 (predicted) Negative Genetic
vps8WD repeat protein Vps8 (predicted) Phenotypic Enhancement
SPAC1952.02ribosome biogenesis protein (predicted) Negative Genetic
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative Genetic
swc2Swr1 complex complex subunit Swc2 Positive Genetic
fft3fun thirty related protein Fft3 Negative Genetic
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative Genetic
SPAC23A1.07ubiquitin-protein ligase E3 (predicted) Positive Genetic
SPAC824.04WD repeat protein (predicted) Negative Genetic
swd1Set1C complex subunit Swd1 Negative Genetic
not2CCR4-Not complex subunit Not2 (predicted) Negative Genetic
amo1nuclear rim protein Amo1 Negative Genetic
nto1histone acetyltransferase complex subunit Nto1 (predicted) Negative Genetic
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative Genetic
dbr1RNA lariat debranching enzyme Dbr1 Negative Genetic
tim13TIM22 inner membrane protein import complex subunit Tim13 (predicted) Negative Genetic
hos2histone deacetylase (class I) Hos2 Synthetic Growth Defect
Negative Genetic
nse6Smc5-6 complex non-SMC subunit Nse6 Synthetic Growth Defect
raf1Rik1-associated factor Raf1 Negative Genetic
snt2Lid2 complex subunit Snt2 Negative Genetic
srb11cyclin CycC, Srb mediator subunit Srb11 Positive Genetic
SPAC631.02bromodomain protein (predicted) Negative Genetic
rpb9DNA-directed RNA polymerase II complex subunit Rpb9 Negative Genetic
sgf29SAGA complex subunit Sgf29 Positive Genetic
slm9hira protein Slm9 Synthetic Growth Defect
ryh1GTPase Ryh1 Synthetic Growth Defect
Negative Genetic
mms19TFIIH regulator Mms19 Negative Genetic
not3CCR4-Not complex subunit Not3/5 (predicted) Negative Genetic
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative Genetic
elp4elongator complex subunit Elp4 (predicted) Negative Genetic
arp6actin-like protein Arp6 Positive Genetic
arp8actin-like protein Arp8 Negative Genetic
msc1multi-copy suppressor of Chk1 Positive Genetic
png2ING family homolog Png2 Synthetic Growth Defect
kap114karyopherin Kap14 Negative Genetic
rik1silencing protein Rik1 Negative Genetic
oca2serine/threonine protein kinase Oca2 Negative Genetic
cpd1tRNA (m1A) methyltransferase complex catalytic subunit Cpd1 Negative Genetic
SPBC31F10.10czf-MYND type zinc finger protein Negative Genetic
iki1elongator complex subunit Iki1 (predicted) Negative Genetic
yaf9YEATS family histone acetyltransferase subunit Yaf9 Positive Genetic
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative Genetic
hip4histone promoter control protein Hip4 Negative Genetic

Physical Interactions from BioGRID

Gene Feature Evidence Source
swr1SNF2 family helicase Swr1 Affinity Capture-MS
stc1LIM-like protein linking chromatin modification to RNAi, Stc1 Affinity Capture-MS
mst1KAT5 family histone acetyltransferase Mst1 Biochemical Activity
msc1multi-copy suppressor of Chk1 Affinity Capture-MS

External References

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Database Identifier Description
NBRP SPBC11B10.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC11B10.10c Retrieval of eukaryotic orthologs
BioGrid SPBC11B10.10c BioGRID Interaction Datasets
Bähler Lab SPBC11B10.10c Cell Cycle Expression Profile
Bähler Lab SPBC11B10.10c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC11B10.10c Pheromone response/mating expression profiles
Bähler Lab SPBC11B10.10c Environmental stress expression profiles
Bähler Lab SPBC11B10.10c Bähler Lab Transcriptome Viewer
Cyclebase SPBC11B10.10c Cell Cycle Data
Entrez Gene SPBC11B10.10c Link to Entrez Gene
SPD / RIKEN41/41D01Orfeome Localization Data
UniProtKB/SwissProtP48003Histone H2A.Z
ArrayExpressP48003Link to ArrayExpress
RefSeq PeptideNP_595630histone H2A variant Pht1
RefSeq mRNANM_001021524972h- histone H2A variant Pht1 (pht1), mRNA
European Nucleotide ArchiveAB004534ENA EMBL mapping
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveS74633ENA EMBL mapping
European Nucleotide ArchiveAAB32938ENA Protein Mapping
European Nucleotide ArchiveBAA21378ENA Protein Mapping
European Nucleotide ArchiveCAC37514ENA Protein Mapping
UniParcUPI000228F3A2UniProt Archive

Literature for pht1

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Search: UK PMC or PubMed