adn2 (SPBC1289.10c)

Gene Standard Nameadn2 ChromosomeII
Systematic IDSPBC1289.10c Gene Start4402885
Synonyms Gene End4400383
Producttranscription factor (predicted) Gene Length2503
Feature Typeprotein coding CDS Start4402847
Name DescriptionADhesioN defective CDS End4400616
Characterisation Statusbiological_role_inferred CDS Length2232

Ensembl Gene Location
  1. ppr8
  2. rpc40
  3. uap1
  4. tim21
  5. adn2
  6. spf38
  7. usp109
  8. SPBC1289.13c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000010abolished cell-substrate adhesionadn2delta (deletion)deletionPMID:19542312
FYPO:0000551pseudohyphal growth abolishedadn2delta (deletion)deletionPMID:19542312
FYPO:0002060viable vegetative cell populationMicroscopyadn2delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingNASGO_REF:0000001
GO:0003697single-stranded DNA bindingISMPFAM:PF04503GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0010811positive regulation of cell-substrate adhesionIMPPMID:19542312
GO:0045944positive regulation of transcription from RNA polymerase II promoterISOSGD:S000000911GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusISOSGD:S000000911GO_REF:0000024
GO:0005737cytoplasmIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
144028854400383

References

Region Start End Reference
three_prime_UTR44006154400383PMID:21511999
five_prime_UTR44028854402848PMID:21511999
three_prime_UTR44006154400383PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF04503 IPR007591 Pfam Single-stranded DNA-binding protein, SSDP 156 700 1
PF08513 IPR013720 Pfam LisH dimerisation motif, subgroup 41 66 8
SM00667 IPR006594 SMART LisH dimerisation motif 38 70 11
PS50896 IPR006594 Prosite Profiles LisH dimerisation motif 38 70 11
Coil ncoils Rabaptin coiled-coil domain 451 472 974
Coil ncoils Rabaptin coiled-coil domain 250 271 974

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Protein Properties

Ave. residue weight 109.23 Da
Charge 6.50
Isoelectric point 7.21
Molecular weight 81.16 kDa
Number of residues 743
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1626.65PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3.5PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi only
conserved in fungi
conserved in eukaryotes
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ppm1leucine carboxyl methyltransferase Ppm1 (predicted) Negative GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
tsc2tuberin Negative GeneticPMID:22681890
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative GeneticPMID:22681890
vph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:22681890
bzz1diacylglycerol binding protein Bzz1 (predicted) Positive GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
SPBC1778.03cNADH pyrophosphatase (predicted) Negative GeneticPMID:22681890
prw1Clr6 histone deacetylase complex subunit Prw1 Negative GeneticPMID:22681890
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
sap10splicing factor 3B Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
ams2cell cycle regulated GATA-type transcription factor Ams2 Positive GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Negative GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
tsc1hamartin Negative GeneticPMID:22681890
sif1Sad1 interacting factor 1 Negative GeneticPMID:22681890
rsv2transcription factor Rsv2 Negative GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
sts5RNB-like protein Negative GeneticPMID:22681890
SPAC1565.07cTATA-binding protein (predicted) Positive GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
raf1Rik1-associated factor Raf1 Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
reb1RNA polymerase I transcription termination factor Reb1 Negative GeneticPMID:22681890
lub1WD repeat protein Lub1 Negative GeneticPMID:22681890
cdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
rpb9DNA-directed RNA polymerase II complex subunit Rpb9 Negative GeneticPMID:22681890
bdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:22681890
sap114U2 snRNP subunit Sap114 Positive GeneticPMID:22681890
gsf2galactose-specific flocculin Gsf2 Phenotypic SuppressionPMID:23236291
pyp1tyrosine phosphatase Pyp1 Positive GeneticPMID:22681890
spc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
SPAC821.05translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
rik1silencing protein Rik1 Negative GeneticPMID:22681890
srb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Positive GeneticPMID:22681890
SPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
ubp2ubiquitin C-terminal hydrolase Ubp2 Negative GeneticPMID:22681890
dad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
int6eIF3e subunit Int6 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
raf2Rik1-associated factor Raf2 Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC1289.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1289.10c Retrieval of eukaryotic orthologs
BioGrid SPBC1289.10c BioGRID Interaction Datasets
Bähler Lab SPBC1289.10c Cell Cycle Expression Profile
Bähler Lab SPBC1289.10c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1289.10c Pheromone response/mating expression profiles
Bähler Lab SPBC1289.10c Environmental stress expression profiles
Bähler Lab SPBC1289.10c Bähler Lab Transcriptome Viewer
Cyclebase SPBC1289.10c Cell Cycle Data
PInt SPBC1289.10c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1289.10c Entrez Gene
EntrezGene2540193transcription factor (predicted)
Uniprot_genenameADN2
WikiGene2540193transcription factor (predicted)
SPD / RIKEN38/38B02Orfeome Localization Data
UniProtKB/SwissProtO94619Adhesion defective protein 2
ModBaseO94619Database of comparative protein structure models
Pfam Protein DomainsO94619Pfam Domain Arrangement
RefSeq PeptideNP_596834transcription factor (predicted)
RefSeq mRNANM_001023855972h- transcription factor (predicted) (adn2), mRNA
European Nucleotide ArchiveCAB38690ENA Protein Mapping
UniParcUPI0000069FF7UniProt Archive

Literature for adn2
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013