rtt10 (SPBC1306.02)

Gene Standard Namertt10 ChromosomeII
Systematic IDSPBC1306.02 Gene Start1180588
SynonymsSPBC4.08 Gene End1184250
ProductWD repeat protein, human WDR6 family, involved in endocytic recycling Gene Length3663
Feature Typeprotein coding CDS Start1181044
Name Description CDS End1184104
Characterisation Statusbiological_role_inferred CDS Length3061

Ensembl Gene Location
  1. psh3
  2. sec66
  3. SPBC1306.01c
  4. rtt10
  5. SPNCRNA.569
  6. dni2
  7. SPBC4.02c
  8. SPBC4.03c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopyrtt10delta (deletion)deletionPMID:20473289
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0008033tRNA processingIEAUniProtKB:KW-0819GO_REF:0000037
GO:0032456endocytic recyclingISOSGD:S000006104GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005768endosomeISOSGD:S000006104GO_REF:0000024
GO:0005829cytosolIDAPMID:16823372
GO:0043234protein complexNASGO_REF:0000051
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
111805881182089
211821431182791
311828451184250

References

Region Start End Reference
three_prime_UTR11841051184250PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00400 IPR001680 Pfam WD40 repeat 283 309 104
PF00400 IPR001680 Pfam WD40 repeat 231 263 104
PF00400 IPR001680 Pfam WD40 repeat 651 676 104
PF00400 IPR001680 Pfam WD40 repeat 190 222 104
SM00320 IPR001680 SMART WD40 repeat 795 836 120
SM00320 IPR001680 SMART WD40 repeat 269 309 120
SM00320 IPR001680 SMART WD40 repeat 895 939 120
SM00320 IPR001680 SMART WD40 repeat 182 222 120
SM00320 IPR001680 SMART WD40 repeat 226 264 120
SM00320 IPR001680 SMART WD40 repeat 686 724 120
SM00320 IPR001680 SMART WD40 repeat 6 43 120
SM00320 IPR001680 SMART WD40 repeat 641 680 120
PS50294 IPR017986 Prosite Profiles WD40-repeat-containing domain 190 318 104
PS50294 IPR017986 Prosite Profiles WD40-repeat-containing domain 648 733 104
PS50082 IPR001680 Prosite Profiles WD40 repeat 648 689 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 284 312 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 190 231 100
G3DSA:2.130.10.10 IPR015943 Gene3D 651 882 144
G3DSA:2.130.10.10 IPR015943 Gene3D 166 416 144
G3DSA:2.130.10.10 IPR015943 Gene3D 17 165 144
G3DSA:2.130.10.10 IPR015943 Gene3D 467 552 144
SSF50978 IPR017986 SuperFamily 622 715 135
SSF50978 IPR017986 SuperFamily 641 762 135
SSF50978 IPR017986 SuperFamily 457 552 135
SSF50978 IPR017986 SuperFamily 779 967 135
SSF50978 IPR017986 SuperFamily 111 407 135
PTHR14344:SF3 hmmpanther 1 984 1
PTHR14344 hmmpanther 1 984 1

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190

Protein Properties

Ave. residue weight 112.78 Da
Charge 10.50
Isoelectric point 7.36
Molecular weight 110.98 kDa
Number of residues 984
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
antisense transcript detected
protein levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide508.6PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide475.54PMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide0.85PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.29PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPBC1306.02 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1306.02 Retrieval of eukaryotic orthologs
BioGrid SPBC1306.02 BioGRID Interaction Datasets
Bähler Lab SPBC1306.02 Cell Cycle Expression Profile
Bähler Lab SPBC1306.02 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1306.02 Pheromone response/mating expression profiles
Bähler Lab SPBC1306.02 Environmental stress expression profiles
Bähler Lab SPBC1306.02 Bähler Lab Transcriptome Viewer
Cyclebase SPBC1306.02 Cell Cycle Data
PInt SPBC1306.02 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1306.02 Entrez Gene
SPD / RIKEN47/47G11Orfeome Localization Data
EntrezGene2539918WD repeat-containing protein
WikiGene2539918WD repeat-containing protein
UniProtKB/SwissProtQ9USZ0Uncharacterized WD repeat-containing protein C1306.02
ModBaseQ9USZ0Database of comparative protein structure models
Pfam Protein DomainsQ9USZ0Pfam Domain Arrangement
RefSeq PeptideNP_595473WD repeat-containing protein
RefSeq mRNANM_001021384972h- WD repeat-containing protein (SPBC1306.02), mRNA
European Nucleotide ArchiveCAB62092ENA Protein Mapping
SPD / RIKEN47/47G11Orfeome Localization Data

Literature for rtt10
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013