ght7 (SPBC1348.14c)

Gene Standard Nameght7 Characterisation Statusbiological_role_inferred
Systematic IDSPBC1348.14c Feature Typeprotein coding
SynonymsSPAC1348.14c, SPAP8B6.01c, SPAPB8B6.01c, SPBPB8B6.01c Name Description
Producthexose transmembrane transporter Ght7 (predicted) Product Size518aa, 57.92 kDa
Genomic Location Chromosome II, 40277-38514 (1764nt); CDS:40143-38587 (1557nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
hexose transmembrane transporter activity6
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
hexose transmembrane transport8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
endoplasmic reticulum596
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane1018
Annotation ExtensionEvidenceWith/FromReference
plasma membrane249
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationght7ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyght7ΔNull3094
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR40277..40144AF017180
3' UTR38586..38514PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 General substrate transporter 12 437 15
TMhelix TMHMM 405 422 959
TMhelix TMHMM 115 137 959
TMhelix TMHMM 80 102 959
TMhelix TMHMM 338 360 959
TMhelix TMHMM 237 259 959
TMhelix TMHMM 274 296 959
TMhelix TMHMM 301 323 959
TMhelix TMHMM 55 75 959
TMhelix TMHMM 373 395 959
TMhelix TMHMM 26 48 959
TMhelix TMHMM 147 169 959
PS00216 Prosite Patterns IPR005829 Sugar transporter, conserved site 288 305 15
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 1 426 55
PTHR24063 HMMPANTHER 1 459 11
PTHR24063:SF337 HMMPANTHER 1 459 8
1.20.1250.20 Gene3D 15 174 72
1.20.1250.20 Gene3D 233 432 72
SSF103473 SuperFamily IPR020846 Major facilitator superfamily domain 14 434 76
PR00171 PRINTS IPR003663 Sugar/inositol transporter 362 374 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 246 256 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 339 360 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 82 101 10
TIGR00879 tigrfam IPR003663 Sugar/inositol transporter 14 433 10

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.82 Da
Charge 6.50
Isoelectric point 7.90
Molecular weight 57.92 kDa
Number of residues 518
Gene Expression

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.012during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
0.022during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4603
conserved in eukaryotes4514

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction witheso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
External References
Database Identifier Description
NBRP SPBC1348.14c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1348.14c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC1348.14c BioGRID Interaction Datasets
Expression Viewer SPBC1348.14c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC1348.14c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC1348.14c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC1348.14c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC1348.14c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC1348.14c Transcriptome Viewer (Bähler Lab)
GEO SPBC1348.14c GEO profiles
PInt SPBC1348.14c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC1348.14c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC1348.14c Fission yeast phenotypic data & analysis
Cyclebase SPBC1348.14c.1 Cell Cycle Data
SPD / RIKEN50/50H01Orfeome Localization Data
UniProtKB/SwissProtQ8TFG1Probable high-affinity hexose transporter ght7
ModBaseQ8TFG1Database of comparative protein structure models
STRINGQ8TFG1Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_001018762hexose transporter Ght7 (predicted)
RefSeq mRNANM_001020937972h- hexose transporter Ght7 (predicted) (ght7), mRNA
European Nucleotide ArchiveCAD27907.1ENA Protein Mapping
UniParcUPI000006CC7CUniProt Archive

Literature for ght7

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015